4WFG
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![BU of 4wfg by Molmil](/molmil-images/mine/4wfg) | Human TRAAK K+ channel in a Tl+ bound conductive conformation | Descriptor: | ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ... | Authors: | Brohawn, S.G, MacKinnon, R. | Deposit date: | 2014-09-15 | Release date: | 2014-12-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Physical mechanism for gating and mechanosensitivity of the human TRAAK K+ channel. Nature, 516, 2014
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5DRW
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![BU of 5drw by Molmil](/molmil-images/mine/5drw) | |
8RMO
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![BU of 8rmo by Molmil](/molmil-images/mine/8rmo) | Crystal structure of anti-FLAG M2 Fab fragment bound to FLAG-tag peptide epitope | Descriptor: | CHLORIDE ION, FLAG-tag, anti-FLAG M2 heavy chain, ... | Authors: | Beugelink, J.W, Janssen, B.J.C, Pronker, M.F. | Deposit date: | 2024-01-08 | Release date: | 2024-04-03 | Last modified: | 2024-07-03 | Method: | X-RAY DIFFRACTION (1.163 Å) | Cite: | Structural Basis for Recognition of the FLAG-tag by Anti-FLAG M2. J.Mol.Biol., 436, 2024
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2IWG
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![BU of 2iwg by Molmil](/molmil-images/mine/2iwg) | COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC | Descriptor: | 52 KDA RO PROTEIN, IG GAMMA-1 CHAIN C, alpha-L-fucopyranose, ... | Authors: | James, L.C, Keeble, A.H, Rhodes, D.A, Trowsdale, J. | Deposit date: | 2006-06-30 | Release date: | 2007-03-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for Pryspry-Mediated Tripartite Motif (Trim) Protein Function. Proc.Natl.Acad.Sci.USA, 104, 2007
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2J6E
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![BU of 2j6e by Molmil](/molmil-images/mine/2j6e) | Crystal Structure of an Autoimmune Complex between a Human IgM Rheumatoid Factor and IgG1 Fc reveals a Novel Fc Epitope and Evidence for Affinity Maturation | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CACODYLATE ION, ... | Authors: | Duquerroy, S, Stura, E.A, Bressanelli, S, Browne, H, Beale, D, Hamon, M, Casali, P, Vaney, M.C, Rey, F.A, Sutton, B.J, Taussig, M.J. | Deposit date: | 2006-09-28 | Release date: | 2007-04-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Crystal structure of a human autoimmune complex between IgM rheumatoid factor RF61 and IgG1 Fc reveals a novel epitope and evidence for affinity maturation. J.Mol.Biol., 368, 2007
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3J3P
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![BU of 3j3p by Molmil](/molmil-images/mine/3j3p) | Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy: 135S Poliovirus and C3-Fab Complex | Descriptor: | C3 antibody, heavy chain, light chain, ... | Authors: | Lin, J, Cheng, N, Hogle, J.M, Steven, A.C, Belnap, D.M. | Deposit date: | 2013-04-10 | Release date: | 2013-07-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (9.1 Å) | Cite: | Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy. J.Immunol., 191, 2013
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5VL3
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![BU of 5vl3 by Molmil](/molmil-images/mine/5vl3) | CD22 d1-d3 in complex with therapeutic Fab Epratuzumab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, B-cell receptor CD22, Epratuzumab Fab Heavy Chain, ... | Authors: | Sicard, T, Ereno-Orbea, J, Julien, J.P. | Deposit date: | 2017-04-24 | Release date: | 2017-10-11 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Molecular basis of human CD22 function and therapeutic targeting. Nat Commun, 8, 2017
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6KS2
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![BU of 6ks2 by Molmil](/molmil-images/mine/6ks2) | Structure of anti-Ghrelin receptor antibody | Descriptor: | Fab7881 Heavy Chain (FabH), Fab7881 Light Chain (FabL) | Authors: | Shiimura, Y, Horita, S, Asada, H, Hirata, K, Iwata, S, Kojima, M. | Deposit date: | 2019-08-23 | Release date: | 2020-08-12 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.753 Å) | Cite: | Structure of an antagonist-bound ghrelin receptor reveals possible ghrelin recognition mode. Nat Commun, 11, 2020
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8GHK
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![BU of 8ghk by Molmil](/molmil-images/mine/8ghk) | |
3J3O
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![BU of 3j3o by Molmil](/molmil-images/mine/3j3o) | Conformational Shift of a Major Poliovirus Antigen Confirmed by Immuno-Cryogenic Electron Microscopy: 160S Poliovirus and C3-Fab Complex | Descriptor: | C3 antibody, heavy chain, light chain, ... | Authors: | Lin, J, Cheng, N, Hogle, J.M, Steven, A.C, Belnap, D.M. | Deposit date: | 2013-04-10 | Release date: | 2013-07-03 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (11.1 Å) | Cite: | Conformational shift of a major poliovirus antigen confirmed by immuno-cryogenic electron microscopy. J.Immunol., 191, 2013
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4QHK
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![BU of 4qhk by Molmil](/molmil-images/mine/4qhk) | UCA (unbound) from CH103 Lineage | Descriptor: | UCA heavy chain, UCA light chain | Authors: | Fera, D, Harrison, S.C. | Deposit date: | 2014-05-28 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.487 Å) | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHN
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![BU of 4qhn by Molmil](/molmil-images/mine/4qhn) | I2 (unbound) from CH103 Lineage | Descriptor: | I2 heavy chain, I2 light chain | Authors: | Fera, D, Harrison, S.C. | Deposit date: | 2014-05-28 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHM
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![BU of 4qhm by Molmil](/molmil-images/mine/4qhm) | I3.1 (unbound) from CH103 Lineage | Descriptor: | I2 light chain, I3 heavy chain | Authors: | Fera, D, Harrison, S.C. | Deposit date: | 2014-05-28 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.23 Å) | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
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4QHL
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![BU of 4qhl by Molmil](/molmil-images/mine/4qhl) | I3.2 (unbound) from CH103 Lineage | Descriptor: | I3 heavy chain, UCA light chain | Authors: | Fera, D, Harrison, S.C. | Deposit date: | 2014-05-28 | Release date: | 2014-06-11 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (3.153 Å) | Cite: | Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains. Proc.Natl.Acad.Sci.USA, 111, 2014
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1UZ6
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![BU of 1uz6 by Molmil](/molmil-images/mine/1uz6) | anti-Lewis X Fab fragment uncomplexed | Descriptor: | IGG FAB (IGG3, KAPPA) HEAVY CHAIN 291-2G3-A, KAPPA) LIGHT CHAIN 291-2G3-A, ... | Authors: | Van Roon, A.M.M, Pannu, N.S, De Vrind, J.P.M, Hokke, C.H, Deelder, A.M, Van Der marel, G.A, Van Boom, J.H, Abrahams, J.P. | Deposit date: | 2004-03-05 | Release date: | 2004-06-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen Structure, 12, 2004
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1FDL
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![BU of 1fdl by Molmil](/molmil-images/mine/1fdl) | |
1AI1
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![BU of 1ai1 by Molmil](/molmil-images/mine/1ai1) | HIV-1 V3 LOOP MIMIC | Descriptor: | AIB142, IGG1-KAPPA 59.1 FAB (HEAVY CHAIN), IGG1-KAPPA 59.1 FAB (LIGHT CHAIN) | Authors: | Ghiara, J.B, Wilson, I.A. | Deposit date: | 1996-11-06 | Release date: | 1997-05-15 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure-based design of a constrained peptide mimic of the HIV-1 V3 loop neutralization site. J.Mol.Biol., 266, 1997
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6S5A
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![BU of 6s5a by Molmil](/molmil-images/mine/6s5a) | CRYSTAL STRUCTURE OF FC P329G LALA WITH ANTI FC P329G FAB | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc P329G LALA, ... | Authors: | Ehler, A, Darowski, D, Jost, C, Stubenrauch, K, Wessels, U, Benz, J, Birk, M, Freimoser-Grundschober, A, Bruenker, P, Moessner, E, Umana, P, Kobold, S, Klein, C. | Deposit date: | 2019-07-01 | Release date: | 2019-09-25 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.72 Å) | Cite: | P329G-CAR-J: a novel Jurkat-NFAT-based CAR-T reporter system recognizing the P329G Fc mutation. Protein Eng.Des.Sel., 32, 2019
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6D4I
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![BU of 6d4i by Molmil](/molmil-images/mine/6d4i) | Crystal Structure of a Fc Fragment of Rhesus macaque (Macaca mulatta) IgG2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Fc fragment of IgG2 | Authors: | Gohain, N, Tolbert, W.D, Pazgier, M. | Deposit date: | 2018-04-18 | Release date: | 2019-05-01 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | From Rhesus macaque to human: structural evolutionary pathways for immunoglobulin G subclasses. Mabs, 11, 2019
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5OGI
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![BU of 5ogi by Molmil](/molmil-images/mine/5ogi) | Complex of a binding protein and human adenovirus C 5 hexon | Descriptor: | 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ... | Authors: | Schmid, M, Ernst, P, Honegger, A, Suomalainen, M, Zimmermann, M, Braun, L, Stauffer, S, Thom, C, Dreier, B, Eibauer, M, Kipar, A, Vogel, V, Greber, U.F, Medalia, O, Plueckthun, A. | Deposit date: | 2017-07-13 | Release date: | 2018-02-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control. Nat Commun, 9, 2018
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1UZ8
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![BU of 1uz8 by Molmil](/molmil-images/mine/1uz8) | anti-Lewis X Fab fragment in complex with Lewis X | Descriptor: | IGG FAB (IGG3, KAPPA) HEAVY CHAIN 291-2G3-A, KAPPA) LIGHT CHAIN 291-2G3-A, ... | Authors: | Van Roon, A.M.M, Pannu, N.S, De Vrind, J.P.M, Hokke, C.H, Deelder, A.M, Van Der marel, G.A, Van Boom, J.H, Abrahams, J.P. | Deposit date: | 2004-03-05 | Release date: | 2004-06-29 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of an Anti-Lewis X Fab Fragment in Complex with its Lewis X Antigen Structure, 12, 2004
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5WCC
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![BU of 5wcc by Molmil](/molmil-images/mine/5wcc) | Crystal structure of the broadly neutralizing Influenza A antibody VRC 315 02-1F07 Fab. | Descriptor: | GLYCEROL, POLYETHYLENE GLYCOL (N=34), SULFATE ION, ... | Authors: | Joyce, M.G, Andrews, S.F, Mascola, J.R, McDermott, A.B, Kwong, P.D. | Deposit date: | 2017-06-29 | Release date: | 2017-12-13 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.461 Å) | Cite: | Preferential induction of cross-group influenza A hemagglutinin stem-specific memory B cells after H7N9 immunization in humans. Sci Immunol, 2, 2017
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5W2B
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![BU of 5w2b by Molmil](/molmil-images/mine/5w2b) | Crystal structure of C-terminal domain of Ebola (Reston) nucleoprotein in complex with Fab fragment | Descriptor: | Fab Heavy Chain, Fab Light Chain, Nucleoprotein | Authors: | Radwanska, M.J, Derewenda, U, Kossiakoff, A.A, Derewenda, Z.S. | Deposit date: | 2017-06-06 | Release date: | 2018-06-13 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The structure of the C-terminal domain of the nucleoprotein from the Bundibugyo strain of the Ebola virus in complex with a pan-specific synthetic Fab. Acta Crystallogr D Struct Biol, 74, 2018
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1HNV
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![BU of 1hnv by Molmil](/molmil-images/mine/1hnv) | STRUCTURE OF HIV-1 RT(SLASH)TIBO R 86183 COMPLEX REVEALS SIMILARITY IN THE BINDING OF DIVERSE NONNUCLEOSIDE INHIBITORS | Descriptor: | 5-CHLORO-8-METHYL-7-(3-METHYL-BUT-2-ENYL)-6,7,8,9-TETRAHYDRO-2H-2,7,9A-TRIAZA-BENZO[CD]AZULENE-1-THIONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) | Authors: | Das, K, Ding, J, Arnold, E. | Deposit date: | 1995-03-30 | Release date: | 1995-07-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors. Nat.Struct.Biol., 2, 1995
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1HNI
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![BU of 1hni by Molmil](/molmil-images/mine/1hni) | STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN A COMPLEX WITH THE NONNUCLEOSIDE INHIBITOR ALPHA-APA R 95845 AT 2.8 ANGSTROMS RESOLUTION | Descriptor: | (2-ACETYL-5-METHYLANILINO)(2,6-DIBROMOPHENYL)ACETAMIDE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) | Authors: | Ding, J, Das, K, Arnold, E. | Deposit date: | 1995-02-28 | Release date: | 1995-06-03 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution. Structure, 3, 1995
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