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6NZO
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BU of 6nzo by Molmil
Set2 bound to nucleosome
Descriptor: DNA (149-MER), Histone H2B 1.1, Histone H3, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2019-02-14
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
3V43
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BU of 3v43 by Molmil
Crystal structure of MOZ
Descriptor: ACETATE ION, Histone H3.1, Histone acetyltransferase KAT6A, ...
Authors:Qiu, Y, Li, F.
Deposit date:2011-12-14
Release date:2012-06-27
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.47 Å)
Cite:Combinatorial readout of unmodified H3R2 and acetylated H3K14 by the tandem PHD finger of MOZ reveals a regulatory mechanism for HOXA9 transcription
Genes Dev., 26, 2012
8H1T
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BU of 8h1t by Molmil
Cryo-EM structure of BAP1-ASXL1 bound to chromatosome
Descriptor: DNA (187-MER), Histone H1.4, Histone H2A type 1-D, ...
Authors:Ge, W, Yu, C, Xu, R.M.
Deposit date:2022-10-04
Release date:2023-02-01
Last modified:2023-04-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Basis of the H2AK119 specificity of the Polycomb repressive deubiquitinase.
Nature, 616, 2023
8HXY
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BU of 8hxy by Molmil
Cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HY0
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BU of 8hy0 by Molmil
Composite cryo-EM structure of the histone deacetylase complex Rpd3S in complex with nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
8HXZ
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BU of 8hxz by Molmil
Cryo-EM structure of Eaf3 CHD in complex with nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
Authors:Cui, H, Wang, H.
Deposit date:2023-01-05
Release date:2023-09-27
Last modified:2023-12-27
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
5GT0
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BU of 5gt0 by Molmil
Crystal structure of nucleosome complex with human testis-specific histone variants, Th2a
Descriptor: CHLORIDE ION, DNA (146-MER), Histone H2A type 1-A, ...
Authors:Kumarevel, T, Sivaraman, P.
Deposit date:2016-08-18
Release date:2017-02-15
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:Structural analyses of the nucleosome complexes with human testis-specific histone variants, hTh2a and hTh2b
Biophys. Chem., 221, 2017
7EA5
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BU of 7ea5 by Molmil
Yeast Set2 bound to a nucleosome containing oncohistone mutations
Descriptor: 601-DNA, Histone H2A, Histone H2B, ...
Authors:Jing, H, Liu, Y.
Deposit date:2021-03-06
Release date:2021-07-14
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
Cell Discov, 7, 2021
6UGM
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BU of 6ugm by Molmil
Structural basis of COMPASS eCM recognition of an unmodified nucleosome
Descriptor: Bre2, DNA (146-MER), H3 N-terminus, ...
Authors:Hsu, P.L, Shi, H, Zheng, N.
Deposit date:2019-09-26
Release date:2019-11-20
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
6VEN
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BU of 6ven by Molmil
Yeast COMPASS in complex with a ubiquitinated nucleosome
Descriptor: 601 DNA (146-MER), COMPASS component BRE2, COMPASS component SDC1, ...
Authors:Worden, E.J, Wolberger, C.
Deposit date:2020-01-02
Release date:2020-01-15
Last modified:2020-01-22
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Structural basis for COMPASS recognition of an H2B-ubiquitinated nucleosome.
Elife, 9, 2020
8JH2
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BU of 8jh2 by Molmil
RNA polymerase II elongation complex bound with Elf1, Spt4/5 and foreign DNA, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (218-MER), DNA (40-MER), DNA-directed RNA polymerase subunit, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (5.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
6UH5
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BU of 6uh5 by Molmil
Structural basis of COMPASS eCM recognition of the H2Bub nucleosome
Descriptor: Bre2, DNA (146-MER), H3 N-terminus, ...
Authors:Hsu, P.L, Shi, H, Zheng, N.
Deposit date:2019-09-26
Release date:2019-11-20
Last modified:2019-12-18
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS.
Mol.Cell, 76, 2019
7UV9
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BU of 7uv9 by Molmil
KDM2A-nucleosome structure stabilized by H3K36C-UNC8015 covalent conjugate
Descriptor: DNA (185-MER), FE (III) ION, Histone H2A type 1, ...
Authors:Spangler, C.J, Skrajna, A, Foley, C.A, Budziszewski, G.R, Azzam, D.N, James, L.I, Frye, S.V, McGinty, R.K.
Deposit date:2022-04-29
Release date:2023-02-22
Last modified:2024-06-12
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of paralog-specific KDM2A/B nucleosome recognition.
Nat.Chem.Biol., 19, 2023
6PX3
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BU of 6px3 by Molmil
Set2 bound to nucleosome
Descriptor: DNA (145-MER), Histone H2B 1.1, Histone H3, ...
Authors:Halic, M, Bilokapic, S.
Deposit date:2019-07-24
Release date:2019-08-28
Last modified:2019-09-04
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Nucleosome and ubiquitin position Set2 to methylate H3K36.
Nat Commun, 10, 2019
7Y5W
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BU of 7y5w by Molmil
Cryo-EM structure of the left-handed Di-tetrasome
Descriptor: Histone H3.1, Histone H4, Widom 601 DNA (147-MER)
Authors:Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
Deposit date:2022-06-17
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7Y61
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BU of 7y61 by Molmil
Cryo-EM structure of the two CAF1LCs bound right-handed Di-tetrasome
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, Z.Y, Yu, C, Xu, R.M.
Deposit date:2022-06-18
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (5.6 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
8Q1H
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BU of 8q1h by Molmil
LSD1 Y391K-CoREST bound to Histone H3 N-terminal tail
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ...
Authors:Barone, M, Mattevi, A.
Deposit date:2023-07-31
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1
To Be Published
8Q1J
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BU of 8q1j by Molmil
LSD1 Y391K-CoREST bound to Acetylated K14 of Histone H3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ...
Authors:Barone, M, Mattevi, A.
Deposit date:2023-07-31
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.87 Å)
Cite:Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1
To Be Published
8Q1G
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BU of 8q1g by Molmil
LSD1-CoREST bound to Acetylated K14 of Histone H3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3C, Lysine-specific histone demethylase 1A, ...
Authors:Barone, M, Mattevi, A.
Deposit date:2023-07-31
Release date:2024-05-15
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Uncoupling Histone Modification Crosstalk by Engineering Lysine Demethylase LSD1
To Be Published
6WKR
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BU of 6wkr by Molmil
PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome
Descriptor: DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ...
Authors:Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R.
Deposit date:2020-04-16
Release date:2021-02-03
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications.
Science, 371, 2021
8TOF
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BU of 8tof by Molmil
Rpd3S bound to an H3K36Cme3 modified nucleosome
Descriptor: Chromatin modification-related protein EAF3, DNA (176-MER), Histone H2A, ...
Authors:Markert, J.W, Vos, S.M, Farnung, L.
Deposit date:2023-08-03
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structure of the complete Saccharomyces cerevisiae Rpd3S-nucleosome complex.
Nat Commun, 14, 2023
7Y60
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BU of 7y60 by Molmil
Cryo-EM structure of human CAF1LC bound right-handed Di-tetrasome
Descriptor: Chromatin assembly factor 1 subunit A, Chromatin assembly factor 1 subunit B, Histone H3.1, ...
Authors:Liu, C.P, Yu, C, Yu, Z.Y, Xu, R.M.
Deposit date:2022-06-18
Release date:2023-08-16
Last modified:2023-09-06
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Structural insights into histone binding and nucleosome assembly by chromatin assembly factor-1.
Science, 381, 2023
7EA8
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BU of 7ea8 by Molmil
Human SETD2 bound to a nucleosome containing oncohistone mutations
Descriptor: 601-DNA, Histone H2A type 1-D, Histone H2B type 2-E, ...
Authors:Jing, H, Liu, Y.
Deposit date:2021-03-06
Release date:2021-07-14
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Cryo-EM structure of SETD2/Set2 methyltransferase bound to a nucleosome containing oncohistone mutations.
Cell Discov, 7, 2021

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