7TAN
Structure of VRK1 C-terminal tail bound to nucleosome core particle
Summary for 7TAN
Entry DOI | 10.2210/pdb7tan/pdb |
EMDB information | 25777 |
Descriptor | Histone H3.2, Histone H4, Histone H2A type 1, ... (7 entities in total) |
Functional Keywords | nucleosome, chromatin, nuclear protein, structural protein-dna-transferase complex, structural protein/dna/transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 12 |
Total formula weight | 314585.58 |
Authors | Spangler, C.J.,Budziszewski, G.R.,McGinty, R.K. (deposition date: 2021-12-21, release date: 2022-05-04, Last modification date: 2024-02-28) |
Primary citation | Budziszewski, G.R.,Zhao, Y.,Spangler, C.J.,Kedziora, K.M.,Williams, M.R.,Azzam, D.N.,Skrajna, A.,Koyama, Y.,Cesmat, A.P.,Simmons, H.C.,Arteaga, E.C.,Strauss, J.D.,Kireev, D.,McGinty, R.K. Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity. Nucleic Acids Res., 50:4355-4371, 2022 Cited by PubMed: 35390161DOI: 10.1093/nar/gkac198 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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