7TAN

Structure of VRK1 C-terminal tail bound to nucleosome core particle

Summary for 7TAN

• Entry DOI: 10.2210/pdb7tan/pdb
• EMDB information: 25777
• Descriptor: Histone H3.2, Histone H4, Histone H2A type 1, ... (7 entities in total)
• Functional Keywords: nucleosome, chromatin, nuclear protein, structural protein-dna-transferase complex, structural protein/dna/transferase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 12
• Total formula weight: 314585.58

Authors

Spangler, C.J.,Budziszewski, G.R.,McGinty, R.K. (deposition date: 2021-12-21, release date: 2022-05-04, Last modification date: 2024-02-28)

• Primary citation: Budziszewski, G.R.,Zhao, Y.,Spangler, C.J.,Kedziora, K.M.,Williams, M.R.,Azzam, D.N.,Skrajna, A.,Koyama, Y.,Cesmat, A.P.,Simmons, H.C.,Arteaga, E.C.,Strauss, J.D.,Kireev, D.,McGinty, R.K.; Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.; Nucleic Acids Res., 50:4355-4371, 2022; PubMed: 35390161; DOI: 10.1093/nar/gkac198

Experimental method

ELECTRON MICROSCOPY (3 Å)