PDB: 226262 resultsInfo pagesStatus searchChemie searchBIRD

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9F3X	CutC choline lyase in complex with cyclopropylcholine Descriptor: Choline trimethylamine-lyase, cyclopropylcholine Authors: Kalnins, G. Deposit date: 2024-04-26 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: CutC choline lyase in complex with fluoromethylcholine To Be Published
9F3W	CutC choline lyase in complex with fluoromethylcholine Descriptor: Choline trimethylamine-lyase, fluoromethylcholine Authors: Kalnins, G. Deposit date: 2024-04-26 Release date: 2024-05-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: CutC choline lyase in complex with fluoromethylcholine To Be Published
9F3E	Single acyclic phosphonate nucleotide (R)-ZNA modification on DNA duplex Descriptor: C modified (R)-ZNA Authors: Li, X, Groaz, E, Herdewyn, P, Lescrinier, E. Deposit date: 2024-04-25 Release date: 2024-06-05 Last modified: 2024-07-10 Method: SOLUTION NMR Cite: Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability. Chemistry, 30, 2024
9F3D	Single acyclic phosphonate nucleotide (S)-ZNA modification on DNA hairpin Descriptor: C modifed (S)-ZNA Authors: Li, X, Groaz, E, Herdewijn, P, Lescrinier, E. Deposit date: 2024-04-25 Release date: 2024-06-05 Last modified: 2024-07-10 Method: SOLUTION NMR Cite: Impact of Single Acyclic Phosphonate Nucleotide (ZNA) Modifications on DNA Duplex Stability. Chemistry, 30, 2024
9F37	Replication-like initiation state of influenza polymerase with GTP and CTP at respectively the -1 and +1 positions (strain A/little yellow-shouldered bat/Guatemala/060/2010/H17N10) Descriptor: 3' end of the vRNA promoter, 5' end of the vRNA promoter, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... Authors: Cusack, S, Drncova, P. Deposit date: 2024-04-25 Release date: 2024-09-18 Method: X-RAY DIFFRACTION (1.905 Å) Cite: High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit Biorxiv, 2024
9F34	Cryo-EM structure of Dopamine 3 receptor:Go complex bound to bitopic FOB02-04A - Conformation B Descriptor: Antibody scFv16, Green fluorescent protein,D(3) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Arroyo-Urea, S, Garcia-Nafria, J. Deposit date: 2024-04-24 Release date: 2024-09-18 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site. Nat Commun, 15, 2024
9F33	Cryo-EM structure of Dopamine 3 Receptor:Go complex bound to bitopic FOB02-04A - Conformation A Descriptor: Antibody scFv16, Green fluorescent protein,D(3) dopamine receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Arroyo-Urea, S, Garcia-Nafria, J. Deposit date: 2024-04-24 Release date: 2024-09-18 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.05 Å) Cite: A bitopic agonist bound to the dopamine 3 receptor reveals a selectivity site. Nat Commun, 15, 2024
9F2R	Influenza A/H17N10 polymerase with bound promoter and 3' end of template in active site Descriptor: 3' end of the promoter vRNA, 5' end of the promoter vRNA, 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, ... Authors: Cusack, S, Drncova, P. Deposit date: 2024-04-23 Release date: 2024-09-18 Method: X-RAY DIFFRACTION (1.959 Å) Cite: High-resolution structure of a replication-initiation like configuration of influenza polymerase active site visualises the essential role of a conserved dibasic motif in the PA subunit To Be Published
9F2K	Myo-inositol-1-phosphate synthase from Thermochaetoides thermophila in complex with NAD Descriptor: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, inositol-3-phosphate synthase Authors: Traeger, T.K, Kyrilis, F.L, Hamdi, F, Kastritis, P.L. Deposit date: 2024-04-23 Release date: 2024-08-14 Last modified: 2024-08-28 Method: ELECTRON MICROSCOPY (2.48 Å) Cite: Disorder-to-order active site capping regulates the rate-limiting step of the inositol pathway. Proc.Natl.Acad.Sci.USA, 121, 2024
9F2C	Archaeal histone protein HTkC from Thermococcus kodakarensis Descriptor: hypothetical protein Authors: Hu, Y, Albrecht, R, Hartmann, M.D. Deposit date: 2024-04-22 Release date: 2024-10-02 Method: X-RAY DIFFRACTION (1.84 Å) Cite: Histones and histone variant families in prokaryotes. Nat Commun, 15, 2024
9F1T	Psychrophilic laccase (multicopper oxidase) from Oenococcus oeni 229 without Histag Descriptor: COPPER (II) ION, Multicopper oxidase Authors: Paredes, F, Casino, P. Deposit date: 2024-04-20 Release date: 2024-08-07 Last modified: 2024-08-21 Method: X-RAY DIFFRACTION (3 Å) Cite: Biochemical and Structural Characterization of a Novel Psychrophilic Laccase (Multicopper Oxidase) Discovered from Oenococcus oeni 229 (ENOLAB 4002). Int J Mol Sci, 25, 2024
9F1S	Structure of UP1 S4ES6E phosphomimetic mutant Descriptor: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed Authors: Dunnett, L, Prischi, F. Deposit date: 2024-04-20 Release date: 2024-05-01 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structure of UP1 S4ES6E phosphomimetic mutant To Be Published
9F1N	First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 46 Descriptor: (2S,4R)-1-[(2S)-2-[9-[2-[4-[2-[2-[2-[4-[3-(dimethylamino)propoxy]phenyl]ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]ethyl]piperazin-1-yl]ethanoylamino]nonanoylamino]-3,3-dimethyl-butanoyl]-N-[[4-(4-methyl-4H-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, Bromodomain-containing protein 4, ... Authors: Balourdas, D.I, Edmonds, A.K, Marsh, G.P, Maple, H.J, Spencer, J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2024-04-19 Release date: 2024-09-11 Method: X-RAY DIFFRACTION (1.71000016 Å) Cite: First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 46 to be published
9F1M	First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45 Descriptor: 1,2-ETHANEDIOL, 1-[2-[7-[2-[4-[2-[2-[2-[4-[3-(dimethylamino)propoxy]phenyl]ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]ethyl]piperazin-1-yl]ethanoylamino]heptanoylamino]-3,3-dimethyl-butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, ... Authors: Balourdas, D.I, Edmonds, A.K, Marsh, G.P, Maple, H.J, Spencer, J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2024-04-19 Release date: 2024-09-11 Method: X-RAY DIFFRACTION (1.90001261 Å) Cite: First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45 to be published
9F1L	First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 35 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[2-[2-[(3R)-2,6-bis(oxidanylidene)piperidin-3-yl]-1,3-bis(oxidanylidene)isoindol-4-yl]oxyethyl]-2-[4-[2-[2-[2-[4-[3-(dimethylamino)propoxy]phenyl]ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]ethyl]piperazin-1-yl]ethanamide Authors: Balourdas, D.I, Edmonds, A.K, Marsh, G.P, Maple, H.J, Spencer, J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2024-04-19 Release date: 2024-09-11 Method: X-RAY DIFFRACTION (1.30000627 Å) Cite: First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 35 to be published
9F1K	First bromodomain of BRD4 in complex with ISOX-DUAL based inhibitor 30 Descriptor: 1,2-ETHANEDIOL, 2-[4-[2-[2-[2-[4-[3-(dimethylamino)propoxy]phenyl]ethyl]-5-(3,5-dimethyl-1,2-oxazol-4-yl)benzimidazol-1-yl]ethyl]piperazin-1-yl]-N-(2-methoxyethyl)ethanamide, Bromodomain-containing protein 4 Authors: Balourdas, D.I, Edmonds, A.K, Marsh, G.P, Maple, H.J, Spencer, J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2024-04-19 Release date: 2024-09-11 Method: X-RAY DIFFRACTION (1.61 Å) Cite: First bromodomain of BRD4 in complex with ISOX-DUAL based inhibitor 30 to be published
9F1J	First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 14 Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, N-[2-[2-[2-[2-[2-[2-[2,6-bis(oxidanylidene)piperidin-3-yl]-1,3-bis(oxidanylidene)isoindol-4-yl]oxyethanoylamino]ethoxy]ethoxy]ethoxy]ethyl]-4-[4-[2-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-(2-morpholin-4-ylethyl)benzimidazol-2-yl]ethyl]phenoxy]butanamide Authors: Balourdas, D.I, Edmonds, A.K, Marsh, G.P, Maple, H.J, Spencer, J, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) Deposit date: 2024-04-19 Release date: 2024-09-11 Method: X-RAY DIFFRACTION (1.13003039 Å) Cite: First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 14 to be published
9F1I	Crystal structure of a first-in-class antibody for alpha-1,6-fucosylated prostate-specific antigen, target bound Descriptor: 1,2-ETHANEDIOL, 2-[2-(2-azanylethoxy)ethoxy]ethanoic acid, Heavy chain rabbit fab, ... Authors: Halldorsson, S. Deposit date: 2024-04-19 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (1.38 Å) Cite: Development of a first-in-class antibody and a specific assay for alpha-1,6-fucosylated prostate-specific antigen. Sci Rep, 14, 2024
9F1G	Remorin protein StREM13_150-198 Descriptor: Remorin Authors: Xu, Z, Habenstein, B. Deposit date: 2024-04-18 Release date: 2024-09-11 Method: SOLUTION NMR Cite: Dynamic pre-structuration of lipid nanodomain-segregating remorin proteins To Be Published
9F1F	Remorin protein StREM13_160-198 Descriptor: Remorin Authors: Xu, Z, Habenstein, B. Deposit date: 2024-04-18 Release date: 2024-09-11 Method: SOLUTION NMR Cite: Dynamic pre-structuration of lipid nanodomain-segregating remorin proteins To Be Published
9F1E	Remorin protein StREM13_171-198 Descriptor: Remorin Authors: Xu, Z, Habenstein, B. Deposit date: 2024-04-18 Release date: 2024-09-11 Method: SOLUTION NMR Cite: Dynamic pre-structuration of lipid nanodomain-segregating remorin proteins To Be Published
9F1D	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E-HYPK Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.26 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1C	Mammalian quaternary complex of a translating 80S ribosome, NAC, MetAP1 and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.78 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F1B	Mammalian ternary complex of a translating 80S ribosome, NAC and NatA/E Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... Authors: Yudin, D, Scaiola, A, Ban, N. Deposit date: 2024-04-18 Release date: 2024-08-21 Last modified: 2024-10-02 Method: ELECTRON MICROSCOPY (3.01 Å) Cite: NAC guides a ribosomal multienzyme complex for nascent protein processing. Nature, 633, 2024
9F18	Crystal structure of a first-in-class antibody for alpha-1,6-fucosylated prostate-specific antigen Descriptor: Heavy chain rabbit fab, Light chain rabbit fab Authors: Halldorsson, S. Deposit date: 2024-04-18 Release date: 2024-07-31 Method: X-RAY DIFFRACTION (2.52 Å) Cite: Development of a first-in-class antibody and a specific assay for alpha-1,6-fucosylated prostate-specific antigen. Sci Rep, 14, 2024

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