9F1M

First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45

This is a non-PDB format compatible entry.

Summary for 9F1M

• Entry DOI: 10.2210/pdb9f1m/pdb
• Descriptor: Bromodomain-containing protein 4, 1,2-ETHANEDIOL, SODIUM ION, ... (5 entities in total)
• Functional Keywords: bromodomain, epigenetic drugs, inhibitor, protacs, vhl, gene regulation
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 65290.72

Authors

Balourdas, D.I.,Edmonds, A.K.,Marsh, G.P.,Maple, H.J.,Spencer, J.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC) (deposition date: 2024-04-19, release date: 2024-09-11)

• Primary citation: Balourdas, D.I.,Edmonds, A.K.,Marsh, G.P.,Maple, H.J.,Spencer, J.,Knapp, S.,Joerger, A.C.,Structural Genomics Consortium (SGC); First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45; to be published,

Experimental method

X-RAY DIFFRACTION (1.90001265923 Å)