9F1M
First bromodomain of BRD4 in complex with ISOX-DUAL based degrader 45
This is a non-PDB format compatible entry.
Functional Information from PROSITE/UniProt
site_id | PS00633 |
Number of Residues | 60 |
Details | BROMODOMAIN_1 Bromodomain signature. AwpFqqpvDavklnlpDYYkiIktpMdmgtIkkrlenny..Ywnaqeciqdfnt.MftNCyiY |
Chain | Residue | Details |
A | ALA80-TYR139 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | SITE: Acetylated histone binding => ECO:0000269|PubMed:22464331 |
Chain | Residue | Details |
A | ASN140 | |
B | ASN140 | |
C | ASN140 | |
D | ASN140 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
Chain | Residue | Details |
A | LYS99 | |
B | LYS99 | |
C | LYS99 | |
D | LYS99 |