PDB: 19228 resultsInfo pagesStatus searchChemie searchBIRD

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5P7U	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 327 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2021-11-17 Method: X-RAY DIFFRACTION (1.098 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P8D	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 346 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (1.179 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5P8S	Automated refinement of diffraction data obtained from an endothiapepsin crystal treated with fragment 361 Descriptor: endothiapepsin Authors: Schiebel, J, Heine, A, Klebe, G. Deposit date: 2016-06-28 Release date: 2016-08-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.109 Å) Cite: High-Throughput Crystallography: Reliable and Efficient Identification of Fragment Hits. Structure, 24, 2016
5TGA	Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... Authors: Melnikov, S, Mailliot, J. Deposit date: 2016-09-27 Release date: 2016-11-23 Last modified: 2016-12-14 Method: X-RAY DIFFRACTION (3.3 Å) Cite: Molecular insights into protein synthesis with proline residues. EMBO Rep., 17, 2016
4MGK	Selective activation of Epac1 and Epac2 Descriptor: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Rap guanine nucleotide exchange factor 4, Ras-related protein Rap-1b, ... Authors: Rehmann, H. Deposit date: 2013-08-28 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Selective activation of Epac1 and Epac2 To be Published
4MGZ	Selective activation of Epac1 and Epac2 Descriptor: (2S,4aR,6R,7R,7aS)-6-[6-amino-8-(benzylsulfanyl)-9H-purin-9-yl]-2-sulfanyltetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol 2-oxide, Rap guanine nucleotide exchange factor 4, Ras-related protein Rap-1b, ... Authors: Rehmann, H. Deposit date: 2013-08-29 Release date: 2014-09-03 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Selective activation of Epac1 and Epac2 To be Published
2CSJ	Solution structure of N-terminal PDZ domain from mouse TJP2 Descriptor: Tjp2 protein Authors: Suetake, T, Hayashi, F, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-21 Release date: 2005-11-21 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution structure of N-terminal PDZ domain from mouse TJP2 To be Published
5M0B	Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with a short-chained N-(2-aminoethyl)isoquinoline-5-sulfonamide) Fasudil-derivative (Ligand 03) Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, METHANOL, N-(2-AMINOETHYL)ISOQUINOLINE-5-SULFONAMIDE, ... Authors: Wienen-Schmidt, B, Heine, A, Klebe, G. Deposit date: 2016-10-04 Release date: 2018-06-06 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.506 Å) Cite: Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with different Fasudil-derivatives To Be Published
7MLX	SARS-CoV-2 programmed -1 frameshifting element three stem H-type pseudoknot Descriptor: BL3-6 Fab Heavy Chain, BL3-6 Fab Light Chain, RNA (65-MER) Authors: Roman, C, Lewicka, A. Deposit date: 2021-04-29 Release date: 2021-08-11 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.09 Å) Cite: The SARS-CoV-2 Programmed -1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 angstrom Using Chaperone-Assisted RNA Crystallography. Acs Chem.Biol., 16, 2021
1Q6X	Crystal structure of rat choline acetyltransferase Descriptor: SODIUM ION, choline O-acetyltransferase Authors: Cai, Y, Rodgers, D.W. Deposit date: 2003-08-14 Release date: 2004-06-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders. Embo J., 23, 2004
1QXH	Crystal Structure of Escherichia coli Thiol Peroxidase in the Oxidized State Descriptor: Thiol peroxidase Authors: Choi, J, Choi, S, Choi, J, Shin, W. Deposit date: 2003-09-06 Release date: 2004-01-20 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Crystal structure of Escherichia coli thiol peroxidase in the oxidized state: insights into intramolecular disulfide formation and substrate binding in atypical 2-Cys peroxiredoxins J.Biol.Chem., 278, 2003
1Q8T	The Catalytic Subunit of cAMP-dependent Protein Kinase (PKA) in Complex with Rho-kinase Inhibitor Y-27632 Descriptor: (R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE, cAMP-dependent protein kinase inhibitor, alpha form, ... Authors: Breitenlechner, C, Gassel, M, Hidaka, H, Kinzel, V, Huber, R, Engh, R.A, Bossemeyer, D. Deposit date: 2003-08-22 Release date: 2003-12-16 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. Structure, 11, 2003
1QD8	COMPLEX OF VANCOMYCIN WITH N-ACETYL GLYCINE Descriptor: ACETYLAMINO-ACETIC ACID, CHLORIDE ION, VANCOMYCIN, ... Authors: Loll, P.J, Kaplan, J, Selinsky, B, Axelsen, P.H. Deposit date: 1999-07-15 Release date: 1999-08-16 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1 Å) Cite: Vancomycin Binding to Low-Affinity Ligands: Delineating a Minimum Set of Interactions Necessary for High-Affinity Binding. J.Med.Chem., 42, 1999
5FPQ	Structure of Homo sapiens acetylcholinesterase phosphonylated by sarin. Descriptor: ACETYLCHOLINESTERASE, PENTAETHYLENE GLYCOL Authors: Allgardsson, A, Berg, L, Akfur, C, Hornberg, A, Worek, F, Linusson, A, Ekstrom, F. Deposit date: 2015-12-02 Release date: 2016-05-11 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of a Prereaction Complex between the Nerve Agent Sarin, its Biological Target Acetylcholinesterase, and the Antidote Hi-6. Proc.Natl.Acad.Sci.USA, 113, 2016
2CT3	Solution Structure of the SH3 domain of the Vinexin protein Descriptor: Vinexin Authors: Miyamoto, K, Tomizawa, T, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) Deposit date: 2005-05-23 Release date: 2005-11-23 Last modified: 2024-05-29 Method: SOLUTION NMR Cite: Solution Structure of the SH3 domain of the Vinexin protein To be Published
6B5N	Structure of PfCSP peptide 25 with human protective antibody CIS43 Descriptor: CIS43 Fab Heavy chain, CIS43 Fab Light chain, pfCSP peptide 25: ASN-VAL-ASP-PRO-ASN-ALA-ASN-PRO-ASN-VAL-ASP Authors: Pancera, M, Weidle, C. Deposit date: 2017-09-29 Release date: 2018-03-21 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.98 Å) Cite: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
6B6W	Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, as-isolated (protein batch 2), oxidized C-cluster Descriptor: CHLORIDE ION, Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, ... Authors: Wittenborn, E.C, Drennan, C.L. Deposit date: 2017-10-03 Release date: 2018-10-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife, 7, 2018
5M71	Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with an (R)-methyl substitued Fasudil-derivative. Descriptor: 5-[[(2~{R})-2-methyl-1,4-diazepan-4-ium-1-yl]sulfonyl]isoquinoline, METHANOL, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Wienen-Schmidt, B, Heine, A, Klebe, G. Deposit date: 2016-10-26 Release date: 2018-06-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.488 Å) Cite: Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with differently methylated Fasudil-derived ligands To be Published
6B6V	Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, as-isolated (protein batch 1), canonical C-cluster Descriptor: Carbon monoxide dehydrogenase, FE(4)-NI(1)-S(4) CLUSTER, FE2/S2 (INORGANIC) CLUSTER, ... Authors: Wittenborn, E.C, Drennan, C.L. Deposit date: 2017-10-03 Release date: 2018-10-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife, 7, 2018
6B9X	Crystal structure of Ragulator Descriptor: Hepatitis B virus x interacting protein, Ragulator complex protein LAMTOR1, Ragulator complex protein LAMTOR2, ... Authors: SU, M.-Y, Hurley, J.H. Deposit date: 2017-10-11 Release date: 2017-11-08 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Hybrid Structure of the RagA/C-Ragulator mTORC1 Activation Complex. Mol. Cell, 68, 2017
6B5O	Structure of PfCSP peptide 29 with human protective antibody CIS43 Descriptor: CIS43 Fab Heavy chain, CIS43 Fab Light chain, PfCSP peptide 29: ASN-PRO-ASN-ALA-ASN-PRO-ASN-ALA-ASN Authors: Pancera, M, Weidle, C. Deposit date: 2017-09-29 Release date: 2018-03-21 Last modified: 2018-04-25 Method: X-RAY DIFFRACTION (2.194 Å) Cite: A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite. Nat. Med., 24, 2018
2D2Z	Crystal structure of Soluble Form Of CLIC4 Descriptor: Chloride intracellular channel protein 4 Authors: Li, Y.F, Li, D.F, Wang, D.C. Deposit date: 2005-09-21 Release date: 2006-05-16 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Trimeric structure of the wild soluble chloride intracellular ion channel CLIC4 observed in crystals Biochem.Biophys.Res.Commun., 343, 2006
1QVA	YEAST INITIATION FACTOR 4A N-TERMINAL DOMAIN Descriptor: INITIATION FACTOR 4A Authors: Johnson, E.R, McKay, D.B. Deposit date: 1999-07-07 Release date: 1999-12-02 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystallographic structure of the amino terminal domain of yeast initiation factor 4A, a representative DEAD-box RNA helicase RNA, 5, 1999
6B6Y	Crystal structure of Desulfovibrio vulgaris carbon monoxide dehydrogenase, dithionite-reduced then oxygen-exposed (protein batch 2), oxidized C-cluster Descriptor: Carbon monoxide dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, Fe(4)-Ni(1)-S(4) cluster, ... Authors: Wittenborn, E.C, Drennan, C.L. Deposit date: 2017-10-03 Release date: 2018-10-03 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife, 7, 2018
5M6Y	Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with a methylisoquinoline Fasudil-derivative Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1,4-diazepan-1-ylsulfonyl)-4-methyl-isoquinoline, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Wienen-Schmidt, B, Heine, A, Klebe, G. Deposit date: 2016-10-26 Release date: 2018-06-06 Last modified: 2024-01-17 Method: X-RAY DIFFRACTION (1.367 Å) Cite: Cocrystal structure of cAMP-dependent Protein Kinase (PKA) in complex with differently methylated Fasudil-derived ligands To be Published

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