8OVE
 
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3J9Z
 | | Activation of GTP Hydrolysis in mRNA-tRNA Translocation by Elongation Factor G | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Li, W, Liu, Z, Koripella, R.K, Langlois, R, Sanyal, S, Frank, J. | | Deposit date: | 2015-03-27 | | Release date: | 2015-07-01 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Activation of GTP hydrolysis in mRNA-tRNA translocation by elongation factor G.
Sci Adv, 1, 2015
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3J6Y
 | | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | Authors: | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2014-04-16 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3JCD
 | | Structure of Escherichia coli EF4 in posttranslocational ribosomes (Post EF4) | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Zhang, D, Yan, K, Liu, G, Song, G, Luo, J, Shi, Y, Cheng, E, Wu, S, Jiang, T, Low, J, Gao, N, Qin, Y. | | Deposit date: | 2015-12-01 | | Release date: | 2016-01-13 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | EF4 disengages the peptidyl-tRNA CCA end and facilitates back-translocation on the 70S ribosome
Nat. Struct. Mol. Biol., 23, 2016
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8PHJ
 | | cA4-bound Cami1 in complex with 70S ribosome | | Descriptor: | 16S rRNA, 23S rRNA (2862-MER), 5S rRNA, ... | | Authors: | Tamulaitiene, G, Mogila, I, Sasnauskas, G, Tamulaitis, G. | | Deposit date: | 2023-06-20 | | Release date: | 2023-12-13 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (3.67 Å) | | Cite: | Ribosomal stalk-captured CARF-RelE ribonuclease inhibits translation following CRISPR signaling.
Science, 382, 2023
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8P2K
 | | Ternary complex of translating ribosome, NAC and METAP1 | | Descriptor: | 18s rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | Authors: | Jia, M, Jaskolowski, M, Scaiola, A, Jomaa, A, Ban, N. | | Deposit date: | 2023-05-16 | | Release date: | 2023-07-19 | | Last modified: | 2024-04-24 | | Method: | ELECTRON MICROSCOPY (2.9 Å) | | Cite: | NAC controls cotranslational N-terminal methionine excision in eukaryotes.
Science, 380, 2023
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3JAG
 | | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | | Deposit date: | 2015-06-10 | | Release date: | 2015-08-12 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.65 Å) | | Cite: | Structural basis for stop codon recognition in eukaryotes.
Nature, 524, 2015
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3JBV
 | | Mechanisms of Ribosome Stalling by SecM at Multiple Elongation Steps | | Descriptor: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | | Authors: | Zhang, J, Pan, X.J, Yan, K.G, Sun, S, Gao, N, Sui, S.F. | | Deposit date: | 2015-10-16 | | Release date: | 2016-01-27 | | Last modified: | 2023-12-27 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Mechanisms of ribosome stalling by SecM at multiple elongation steps
Elife, 4, 2015
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8P2F
 | | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane in post-translocational state | | Descriptor: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ... | | Authors: | Gonzalez-Lopez, A, Selmer, M. | | Deposit date: | 2023-05-16 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.44 Å) | | Cite: | Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep, 14, 2024
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8P2G
 | | Staphylococcus aureus 70S ribosome with elongation factor G locked with fusidic acid cyclopentane with a tRNA in pe/E chimeric state | | Descriptor: | 1,4-DIAMINOBUTANE, 16S ribosomal RNA, 2-[(3~{R},4~{S},5~{S},8~{S},9~{S},10~{S},11~{R},13~{S},14~{S},16~{S})-16-acetyloxy-4,8,10,14-tetramethyl-3,11-bis(oxidanyl)-1,2,3,4,5,6,7,9,11,12,13,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5-cyclopentyl-pentanoic acid, ... | | Authors: | Gonzalez-Lopez, A, Selmer, M. | | Deposit date: | 2023-05-16 | | Release date: | 2024-05-01 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.02 Å) | | Cite: | Structures of the Staphylococcus aureus ribosome inhibited by fusidic acid and fusidic acid cyclopentane.
Sci Rep, 14, 2024
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8P2H
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8OVJ
 | | CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : PARENTAL STRAIN | | Descriptor: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | | Authors: | Rajan, K.S, Yonath, A. | | Deposit date: | 2023-04-26 | | Release date: | 2024-05-08 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.4 Å) | | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification.
Cell Rep, 43, 2024
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8P18
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure III) | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | Deposit date: | 2023-05-11 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
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8P16
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure I) | | Descriptor: | 1,4-DIAMINOBUTANE, 16S rRNA, 23S rRNA, ... | | Authors: | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | Deposit date: | 2023-05-11 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.77 Å) | | Cite: | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
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8P17
 | | E167K RF2 on E. coli 70S release complex with UGG (Structure II) | | Descriptor: | 1,4-DIAMINOBUTANE, 16S RNA, 23S rRNA, ... | | Authors: | Pundir, S, Larsson, D.S.D, Selmer, M, Sanyal, S. | | Deposit date: | 2023-05-11 | | Release date: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (2.78 Å) | | Cite: | The compensatory mechanism of a naturally evolved
E167K RF2 counteracting the loss of
RF1 in bacteria
To Be Published
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3JBP
 | | Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to E-tRNA | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | | Deposit date: | 2015-09-16 | | Release date: | 2015-10-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
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3J7P
 | | Structure of the 80S mammalian ribosome bound to eEF2 | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | | Deposit date: | 2014-08-01 | | Release date: | 2014-09-03 | | Last modified: | 2018-07-18 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157, 2014
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3JAM
 | | CryoEM structure of 40S-eIF1A-eIF1 complex from yeast | | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | | Deposit date: | 2015-06-17 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.46 Å) | | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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3JCJ
 | | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association | | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | Authors: | Sprink, T, Ramrath, D.J.F, Yamamoto, H, Yamamoto, K, Loerke, J, Ismer, J, Hildebrand, P.W, Scheerer, P, Buerger, J, Mielke, T, Spahn, C.M.T. | | Deposit date: | 2015-12-18 | | Release date: | 2016-03-09 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | Structures of ribosome-bound initiation factor 2 reveal the mechanism of subunit association.
Sci Adv, 2, 2016
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8PKL
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8PEG
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3J6X
 | | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | | Authors: | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | | Deposit date: | 2014-04-16 | | Release date: | 2014-06-11 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (6.1 Å) | | Cite: | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111, 2014
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3JBN
 | | Cryo-electron microscopy reconstruction of the Plasmodium falciparum 80S ribosome bound to P-tRNA | | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein eS1, ... | | Authors: | Sun, M, Li, W, Blomqvist, K, Das, S, Hashem, Y, Dvorin, J.D, Frank, J. | | Deposit date: | 2015-09-16 | | Release date: | 2015-10-14 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.7 Å) | | Cite: | Dynamical features of the Plasmodium falciparum ribosome during translation.
Nucleic Acids Res., 43, 2015
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3J80
 | | CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | | Authors: | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | | Deposit date: | 2014-08-28 | | Release date: | 2014-11-05 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (3.75 Å) | | Cite: | Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159, 2014
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3JAP
 | | Structure of a partial yeast 48S preinitiation complex in closed conformation | | Descriptor: | 18S rRNA, MAGNESIUM ION, METHIONINE, ... | | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | | Deposit date: | 2015-06-18 | | Release date: | 2015-08-12 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (4.9 Å) | | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol.Cell, 59, 2015
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