PDB: 619 resultsInfo pagesStatus searchChemie searchBIRD

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8DTO	Vaccine elicited Antibody MU89 bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Stalls, V, Acharya, P. Deposit date: 2022-07-26 Release date: 2023-04-19 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.57 Å) Cite: Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction. Cell Host Microbe, 32, 2024
5V5N	Crystal structure of Takinib bound to TAK1 Descriptor: Mitogen-activated protein kinase kinase kinase 7/TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 chimera, N~1~-(1-propyl-1,3-dihydro-2H-benzimidazol-2-ylidene)benzene-1,3-dicarboxamide Authors: Gurbani, D, Westover, K, Bera, A.K. Deposit date: 2017-03-14 Release date: 2017-08-30 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.006 Å) Cite: Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-alpha Inhibition for Cancer and Autoimmune Disease. Cell Chem Biol, 24, 2017
8EL7	CryoEM structure of Resistance to Inhibitors of Cholinesterase-8B (Ric-8B) in complex with G alpha s Descriptor: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, Isoform 1 of Synembryn-B Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2022-09-23 Release date: 2023-03-01 Last modified: 2024-11-06 Method: ELECTRON MICROSCOPY (2.8 Å) Cite: Structures of Ric-8B in complex with G alpha protein folding clients reveal isoform specificity mechanisms. Structure, 31, 2023
8EL8	CryoEM structure of Resistance to Inhibitors of Cholinesterase-8B (Ric-8B) in complex with olfactory G protein alpha olf Descriptor: Guanine nucleotide-binding protein G(olf) subunit alpha, Isoform 1 of Synembryn-B Authors: Papasergi-Scott, M.M, Skiniotis, G. Deposit date: 2022-09-23 Release date: 2023-03-01 Last modified: 2024-10-09 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Structures of Ric-8B in complex with G alpha protein folding clients reveal isoform specificity mechanisms. Structure, 31, 2023
8EHR	Cryo-EM reconstruction of the CFA/I bacterial adhesion pili Descriptor: CFA/I fimbrial subunit B Authors: Doran, M.H, Bullitt, E. Deposit date: 2022-09-14 Release date: 2023-03-22 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: Three structural solutions for bacterial adhesion pilus stability and superelasticity. Structure, 31, 2023
8EHT	Cryo-EM reconstruction of the CS20 bacterial adhesion pili Descriptor: CS20 fimbria major subunit protein Authors: Doran, M.H, Bullitt, E. Deposit date: 2022-09-14 Release date: 2023-03-22 Last modified: 2024-10-23 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Three structural solutions for bacterial adhesion pilus stability and superelasticity. Structure, 31, 2023
8DY6	Vaccine elicited Antibody MU89+S27Y bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Stalls, V, Acharya, P. Deposit date: 2022-08-03 Release date: 2023-04-19 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (4.32 Å) Cite: Mutation-guided vaccine design: A process for developing boosting immunogens for HIV broadly neutralizing antibody induction. Cell Host Microbe, 32, 2024
6MGN	mouse Id1 (51-104) - human hE47 (348-399) complex Descriptor: DNA-binding protein inhibitor ID-1, Transcription factor E2-alpha Authors: Benezra, R, Pavletich, N.P, Gall, A.-L, Goldgur, Y. Deposit date: 2018-09-14 Release date: 2019-09-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.901 Å) Cite: A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep, 29, 2019
5UWD	Crystal structure of EGFR kinase domain (L858R, T790M, V948R) in complex with the covalent inhibitor CO-1686 Descriptor: Epidermal growth factor receptor, N-(3-{[2-{[4-(4-acetylpiperazin-1-yl)-2-methoxyphenyl]amino}-5-(trifluoromethyl)pyrimidin-4-yl]amino}phenyl)propanamide Authors: Gajiwala, K.S, Ferre, R.A. Deposit date: 2017-02-21 Release date: 2017-10-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.06 Å) Cite: Proteome-wide Map of Targets of T790M-EGFR-Directed Covalent Inhibitors. Cell Chem Biol, 24, 2017
6LYC	Crystal structure of the NOD SIRPa complex with D4-2 Descriptor: ACETIC ACID, D4-2, SIRPa of the NOD mouse strain Authors: Murata, Y, Matsuda, M, Nakagawa, A, Matozaki, T. Deposit date: 2020-02-14 Release date: 2020-07-01 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.36 Å) Cite: Macrocyclic Peptide-Mediated Blockade of the CD47-SIRP alpha Interaction as a Potential Cancer Immunotherapy. Cell Chem Biol, 27, 2020
5VH5	Crystal Structure of Fc fragment of anti-TNFa antibody infliximab Descriptor: ACETATE ION, Infliximab Fc, ZINC ION, ... Authors: Mayclin, S.J, Edwards, T.E, Lerch, T.F, Conlan, H, Sharpe, P. Deposit date: 2017-04-12 Release date: 2017-05-03 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Infliximab crystal structures reveal insights into self-association. MAbs, 9, 2017
8E6O	Crystal structure of human GCN5 histone acetyltransferase domain Descriptor: Histone acetyltransferase KAT2A, S-{(3S,5R,9R)-1-[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)oxolan-2-yl]-3,5,9-trihydroxy-8,8-dimethyl-3,5,10,14-tetraoxo-2,4,6-trioxa-11,15-diaza-3lambda~5~,5lambda~5~-diphosphaheptadecan-17-yl} (2R)-2-hydroxypropanethioate Authors: Lu, X.T, Tao, Y.J. Deposit date: 2022-08-23 Release date: 2024-02-28 Last modified: 2025-08-27 Method: X-RAY DIFFRACTION (2.37 Å) Cite: ACSS2 acts as a lactyl-CoA synthetase and couples KAT2A to function as a lactyltransferase for histone lactylation and tumor immune evasion. Cell Metab., 37, 2025
6MFR	Human Argonaute2-miR-122 bound to a target RNA with three central mismatches (bu3) Descriptor: PHENOL, PHOSPHATE ION, Protein argonaute-2, ... Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-09-12 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
3NXY	Preferential Selection of Isomer Binding from Chiral Mixtures: Alernate Binding Modes Observed fro the E- and Z-isomers of a Series of 5-Substituted 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Human Dihydrofolate Reductase Descriptor: 5-[(1E,3R)-2-(2-methoxyphenyl)-3-methylpent-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine, Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... Authors: Cody, V. Deposit date: 2010-07-14 Release date: 2010-12-15 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Preferential selection of isomer binding from chiral mixtures: alternate binding modes observed for the E and Z isomers of a series of 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines as ternary complexes with NADPH and human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 66, 2010
1VXA	NATIVE SPERM WHALE MYOGLOBIN Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Yang, F, Phillips Jr, G.N. Deposit date: 1996-01-09 Release date: 1996-08-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structures of CO-, deoxy- and met-myoglobins at various pH values. J.Mol.Biol., 256, 1996
8EHS	Cryo-EM reconstruction of the CS17 bacterial adhesion pili Descriptor: CS17 fimbriae major subunit Authors: Doran, M.H, Bullitt, E. Deposit date: 2022-09-14 Release date: 2023-03-22 Last modified: 2024-06-19 Method: ELECTRON MICROSCOPY (3.3 Å) Cite: Three structural solutions for bacterial adhesion pilus stability and superelasticity. Structure, 31, 2023
8DGX	Crystal structure of MERS-CoV spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC68.109 isolated from a vaccinated COVID-19 convalescent Descriptor: Antibody CC68.109 Fab heavy chain, Antibody CC68.109 Fab light chain, Spike protein S2' Authors: Liu, H, Wilson, I.A. Deposit date: 2022-06-24 Release date: 2023-01-25 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.89 Å) Cite: Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity, 56, 2023
8DGW	Crystal structure of HCoV-HKU1 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC95.108 isolated from a vaccinated COVID-19 convalescent Descriptor: Antibody CC95.108 Fab heavy chain, Antibody CC95.108 Fab light chain, Spike protein S2' Authors: Liu, H, Wilson, I.A. Deposit date: 2022-06-24 Release date: 2023-01-25 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.81 Å) Cite: Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity, 56, 2023
8DGU	Crystal structure of SARS-CoV-2 spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC25.106 isolated from a vaccinated COVID-19 convalescent Descriptor: Antibody CC25.106 Fab heavy chain, Antibody CC25.106 Fab light chain, GLYCEROL, ... Authors: Liu, H, Wilson, I.A. Deposit date: 2022-06-24 Release date: 2023-01-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.89 Å) Cite: Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity, 56, 2023
8DGV	Crystal structure of MERS-CoV spike stem helix peptide in complex with Fab of broadly neutralizing antibody CC99.103 isolated from a vaccinated COVID-19 convalescent Descriptor: Antibody CC99.103 Fab heavy chain, Antibody CC99.103 Fab light chain, Spike protein S2' Authors: Liu, H, Wilson, I.A. Deposit date: 2022-06-24 Release date: 2023-01-25 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease. Immunity, 56, 2023
3MBA	APLYSIA LIMACINA MYOGLOBIN. CRYSTALLOGRAPHIC ANALYSIS AT 1.6 ANGSTROMS RESOLUTION Descriptor: FLUORIDE ION, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE Authors: Bolognesi, M, Onesti, S, Gatti, G, Coda, A, Ascenzi, P, Brunori, M. Deposit date: 1989-02-22 Release date: 1990-01-15 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Aplysia limacina myoglobin. Crystallographic analysis at 1.6 A resolution. J.Mol.Biol., 205, 1989
5UIZ	Structure of T.fusca AA10A Descriptor: AA10A, COPPER (II) ION, GLYCEROL, ... Authors: Alahuhta, P.M, Lunin, V.V. Deposit date: 2017-01-16 Release date: 2017-02-01 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of a Thermobifida fusca lytic polysaccharide monooxygenase and mutagenesis of key residues. Biotechnol Biofuels, 10, 2017
6MDZ	Human Argonaute2-miR-122 bound to a target RNA with two central mismatches (bu2) Descriptor: PHENOL, Protein argonaute-2, RNA (5'-R(P*AP*AP*AP*CP*AP*CP*CP*AP*UP*UP*UP*CP*CP*AP*CP*AP*CP*UP*CP*CP*AP*AP*A)-3'), ... Authors: Sheu-Gruttadauria, J, MacRae, I.J. Deposit date: 2018-09-05 Release date: 2019-08-07 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.4 Å) Cite: Structural Basis for Target-Directed MicroRNA Degradation. Mol.Cell, 75, 2019
6MGM	Helix-Loop-helix motif of mouse DNA-binding protein inhibitor ID-1 Descriptor: DNA-binding protein inhibitor ID-1 Authors: Benezra, R, Pavletich, N.P, Goldgur, Y, Gall, A.-L. Deposit date: 2018-09-14 Release date: 2019-09-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (1.791 Å) Cite: A Small-Molecule Pan-Id Antagonist Inhibits Pathologic Ocular Neovascularization. Cell Rep, 29, 2019
1VXD	NATIVE SPERM WHALE MYOGLOBIN Descriptor: MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, SULFATE ION Authors: Yang, F, Phillips Jr, G.N. Deposit date: 1996-01-09 Release date: 1996-08-01 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structures of CO-, deoxy- and met-myoglobins at various pH values. J.Mol.Biol., 256, 1996

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