PDB: 659 resultsInfo pagesStatus searchChemie searchBIRD

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7QRS	Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 Descriptor: ACETATE ION, GLYCEROL, Protein Tax-1, ... Authors: Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. Deposit date: 2022-01-12 Release date: 2022-09-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.77 Å) Cite: Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
7QRT	Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 Descriptor: CHLORIDE ION, Protein Tax-1, Protein scribble homolog, ... Authors: Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M, Maddumage, J.C. Deposit date: 2022-01-12 Release date: 2022-09-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
7QS8	Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 Descriptor: Protein Tax-1, Protein scribble homolog Authors: Javorsky, A, Soares da Costa, T.P, Mackie, E.R, Humbert, P.O, Kvansakul, M. Deposit date: 2022-01-13 Release date: 2022-09-07 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.85 Å) Cite: Structural insight into the Scribble PDZ domains interaction with the oncogenic Human T-cell lymphotrophic virus-1 (HTLV-1) Tax1 PBM. Febs J., 290, 2023
7QS9	Structural basis on the interaction of Scribble PDZ domains with the Tick Born encephalitis virus (TBEV) NS5 protein Descriptor: Protein scribble homolog, RNA-directed RNA polymerase NS5 Authors: Javorsky, A, Humbert, P.O, Kvansakul, M. Deposit date: 2022-01-13 Release date: 2022-08-31 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Molecular basis of Tick Born encephalitis virus NS5 mediated subversion of apico-basal cell polarity signalling. Biochem.J., 479, 2022
7RM8	Solution NMR structure of PDLIM7 PDZ bound to SNX17 peptide Descriptor: Isoform 4 of PDZ and LIM domain protein 7,Sorting nexin-17 fusion Authors: Healy, M.D, Collins, B.M, Mobli, M. Deposit date: 2021-07-26 Release date: 2022-08-31 Last modified: 2024-05-15 Method: SOLUTION NMR Cite: Proteomic identification and structural basis for the interaction between sorting nexin SNX17 and PDLIM family proteins. Structure, 30, 2022
7R2M	SYNJ2BP complex with a synthetic Vangl2 peptide (9mer). Descriptor: 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, GLYCEROL, ... Authors: Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. Deposit date: 2022-02-04 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.4 Å) Cite: SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published
7R2T	SYNJ2BP complex with a phosphorylated Vangl2 peptide at the P-1 position. Descriptor: CALCIUM ION, GLYCEROL, Synaptojanin-2-binding protein,Annexin, ... Authors: Carrasco, K, Cousido Siah, A, Gogl, G, Betzi, S, McEwen, A, Kostmann, C, Trave, G. Deposit date: 2022-02-05 Release date: 2023-05-17 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.5 Å) Cite: SYNJ2BP PDZ domain in complex with a synthetic Vangl2 peptide. To Be Published
4NXP	Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) Descriptor: T-lymphoma invasion and metastasis-inducing protein 1 Authors: Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J. Deposit date: 2013-12-09 Release date: 2015-05-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2016
4OEP	Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail Descriptor: ACETATE ION, DODECAETHYLENE GLYCOL, Tight junction protein ZO-1 Authors: Nomme, J, Lavie, A. Deposit date: 2014-01-13 Release date: 2015-01-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. J.Biol.Chem., 290, 2015
4P0C	Crystal Structure of NHERF2 PDZ1 Domain in Complex with LPA2 Descriptor: CHLORIDE ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF2/Lysophosphatidic acid receptor 2 chimeric protein, THIOCYANATE ION Authors: Holcomb, J, Jiang, Y, Lu, G, Trescott, L, Brunzelle, J, Sirinupong, N, Li, C, Naren, A, Yang, Z. Deposit date: 2014-02-20 Release date: 2014-05-21 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.339 Å) Cite: Structural insights into PDZ-mediated interaction of NHERF2 and LPA2, a cellular event implicated in CFTR channel regulation. Biochem.Biophys.Res.Commun., 446, 2014
4OAJ	Crystal structure of the complex between SAP97 PDZ2 and 5HT2A receptor peptide Descriptor: 5-hydroxytryptamine receptor 2A peptide, Disks large homolog 1 Authors: Pandalaneni, S, Dorr, L, Mayans, O, Lian, L.-Y. Deposit date: 2014-01-04 Release date: 2014-01-29 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Crystal structure of the complex between SAP97 PDZ2 and 5HT2A receptor peptide To be Published
4Q2Q	ZO1 PDZ3 in Complex with a Phage-Derived Peptide Descriptor: Tight junction protein ZO-1 Authors: Appleton, B.A, Wiesmann, C. Deposit date: 2014-04-09 Release date: 2014-09-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.45 Å) Cite: A structural portrait of the PDZ domain family. J.Mol.Biol., 426, 2014
4Q2O	PDLIM4 PDZ in Complex with a Phage-Derived Peptide Descriptor: PDZ and LIM domain protein 4 Authors: Appleton, B.A, Wiesmann, C. Deposit date: 2014-04-09 Release date: 2014-09-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: A structural portrait of the PDZ domain family. J.Mol.Biol., 426, 2014
4Q6H	CFTR Associated Ligand (CAL) bound to last 6 residues of CFTR (decameric peptide: iCAL36VQDTRL) Descriptor: CFTR-associated ligand, SULFITE ION, iCAL36-VQDTRL peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2014-04-22 Release date: 2014-05-14 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.903 Å) Cite: Understanding PDZ Affinity and Selectivity: All Residues Considered TO BE PUBLISHED
4Q6S	CFTR Associated Ligand (CAL) PDZ bound to biotinylated peptide BT-L-iCAL36 Descriptor: BT-L-iCAL36 peptide, Golgi-associated PDZ and coiled-coil motif-containing protein Authors: Amacher, J.F, Madden, D.R. Deposit date: 2014-04-23 Release date: 2015-04-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Modulator Preferences are Critical Co-Determinants of PDZ Network Wiring To be Published
4O06	1.15A Resolution Structure of the Proteasome Assembly Chaperone Nas2 PDZ Domain Descriptor: Probable 26S proteasome regulatory subunit p27, SULFATE ION, TETRAETHYLENE GLYCOL Authors: Lovell, S, Mehzabeen, N, Battaile, K.P, Singh, C.R, Chowdhury, W.Q, Geanes, E, Roelofs, J. Deposit date: 2013-12-13 Release date: 2014-04-16 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.15 Å) Cite: 1.15 angstrom resolution structure of the proteasome-assembly chaperone Nas2 PDZ domain. Acta Crystallogr F Struct Biol Commun, 70, 2014
4NXR	Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM) in Complex With Neurexin-1 Peptide Descriptor: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5-(DIMETHYLAMINO)-1-NAPHTHALENESULFONIC ACID(DANSYL ACID), Neurexin-2-beta Peptide, ... Authors: Liu, X, Speckhard, D.C, Shepherd, T.R, Hengel, S.R, Fuentes, E.J. Deposit date: 2013-12-09 Release date: 2015-05-13 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24, 2016
4NMP	CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36(Ac-K-3) (ANSRWP[Ac-K]SII) Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36(Ac-K-3) peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2013-11-15 Release date: 2014-10-01 Last modified: 2023-12-06 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain. Plos One, 9, 2014
4NMR	CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36(Ac-K-5) (ANSR[Ac-K]PTSII) Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36(Ac-K-5) peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2013-11-15 Release date: 2014-10-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.55 Å) Cite: Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain. Plos One, 9, 2014
4NMT	CFTR Associated Ligand (CAL) PDZ domain bound to peptide iCAL36(TFA-K-1) (ANSRWPTS[Tfa-acyl-K]I) Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36(TFA-K-1) peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2013-11-15 Release date: 2014-10-01 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain. Plos One, 9, 2014
4NMS	CFTR Associated Ligand (CAL)PDZ domain bound to peptide iCAL36(FLB-K-1) (ANSRWPTS[4-fluorobenzoic-acyl-K]I) Descriptor: GLYCEROL, Golgi-associated PDZ and coiled-coil motif-containing protein, iCAL36(FLB-K-1) peptide Authors: Amacher, J.F, Madden, D.R. Deposit date: 2013-11-15 Release date: 2014-10-01 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Chemically Modified Peptide Scaffolds Target the CFTR-Associated Ligand PDZ Domain. Plos One, 9, 2014
4NNL	Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide Descriptor: TIP-1 PDZ domain, Tax1-binding protein 3 Authors: Amacher, J.F, Madden, D.R. Deposit date: 2013-11-18 Release date: 2015-01-21 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.5 Å) Cite: A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR To be Published
4OEO	High resolution crystal structure of the unliganded ZO-1 PDZ1 domain Descriptor: ACETATE ION, DODECAETHYLENE GLYCOL, SULFATE ION, ... Authors: Nomme, J, Lavie, A. Deposit date: 2014-01-13 Release date: 2015-01-14 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. J.Biol.Chem., 290, 2015
4PQW	Crystal Structure of Phospholipase C beta 3 in Complex with PDZ1 of NHERF1 Descriptor: CHLORIDE ION, NICKEL (II) ION, Na(+)/H(+) exchange regulatory cofactor NHE-RF1 Authors: Jiang, Y, Wang, S, Holcomb, J, Trescott, L, Guan, X, Hou, Y, Brunzelle, J, Sirinupong, N, Li, C, Yang, Z. Deposit date: 2014-03-04 Release date: 2014-04-02 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Crystallographic analysis of NHERF1-PLC beta 3 interaction provides structural basis for CXCR2 signaling in pancreatic cancer. Biochem.Biophys.Res.Commun., 446, 2014
4Q2P	NHERF3 PDZ2 in Complex with a Phage-Derived Peptide Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Na(+)/H(+) exchange regulatory cofactor NHE-RF3 Authors: Appleton, B.A, Wiesmann, C. Deposit date: 2014-04-09 Release date: 2014-09-10 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: A structural portrait of the PDZ domain family. J.Mol.Biol., 426, 2014

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