4OEP
Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail
Summary for 4OEP
Entry DOI | 10.2210/pdb4oep/pdb |
Related | 4OEO 4OEQ |
Descriptor | Tight junction protein ZO-1, DODECAETHYLENE GLYCOL, ACETATE ION, ... (4 entities in total) |
Functional Keywords | maguk, pdz1, scaffolding, cell adhesion, claudin, tight junction assembly |
Biological source | Homo sapiens (human) |
Cellular location | Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157 |
Total number of polymer chains | 2 |
Total formula weight | 23614.49 |
Authors | |
Primary citation | Nomme, J.,Antanasijevic, A.,Caffrey, M.,Van Itallie, C.M.,Anderson, J.M.,Fanning, A.S.,Lavie, A. Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins. J.Biol.Chem., 290:16595-16606, 2015 Cited by PubMed: 26023235DOI: 10.1074/jbc.M115.646695 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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