4OEO

High resolution crystal structure of the unliganded ZO-1 PDZ1 domain

Summary for 4OEO

• Entry DOI: 10.2210/pdb4oeo/pdb
• Related: 4OEP 4OEQ
• Descriptor: Tight junction protein ZO-1, ACETATE ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: maguk, pdz1, scaffolding, cell adhesion, claudin, tight junction assembly
• Biological source: Homo sapiens (human)
• Cellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side: Q07157
• Total number of polymer chains: 3
• Total formula weight: 35923.27

Authors

Nomme, J.,Lavie, A. (deposition date: 2014-01-13, release date: 2015-01-14, Last modification date: 2024-02-28)

• Primary citation: Nomme, J.,Antanasijevic, A.,Caffrey, M.,Van Itallie, C.M.,Anderson, J.M.,Fanning, A.S.,Lavie, A.; Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins.; J.Biol.Chem., 290:16595-16606, 2015; PubMed: 26023235; DOI: 10.1074/jbc.M115.646695

Experimental method

X-RAY DIFFRACTION (1.9 Å)