4OEO

High resolution crystal structure of the unliganded ZO-1 PDZ1 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	Tight junction protein ZO-1	polymer	107	11486.9	3	UniProt (Q07157) Pfam (PF00595) In PDB	Homo sapiens (human)	Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1
2	A, B	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
3	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4	B, C	DODECAETHYLENE GLYCOL	non-polymer		546.6	2	Chemie (12P)
5		water	water		18.0	96	Chemie (HOH)

Sequence modifications

A, B, C: 18 - 110 (UniProt: Q07157)

PDB	External Database	Details
Gly 14	-	expression tag
Ser 15	-	expression tag
His 16	-	expression tag
Met 17	-	expression tag
Gly 111	-	expression tag
Gly 112	-	expression tag
Gly 113	-	expression tag
Glu 114	-	expression tag
Ser 115	-	expression tag
Leu 116	-	expression tag
Thr 117	-	expression tag
Gly 118	-	expression tag
Tyr 119	-	expression tag
Val 120	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	34460.7
Non-Polymers*	Number of molecules	7
	Total formula weight	1462.5
All*	Total formula weight	35923.3

*Water molecules are not included.