4OEP
Crystal structure of the ZO-1 PDZ1 domain in complex with the 7-mer Claudin1 C-terminal tail
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Tight junction protein ZO-1 | polymer | 107 | 11474.9 | 2 | UniProt (Q07157) Pfam (PF00595) | Homo sapiens (human) | Tight junction protein 1, Zona occludens protein 1, Zonula occludens protein 1 |
| 2 | C (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 1 | Chemie (12P) | |||
| 3 | D, E (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 4 | F, G (A, B) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A, B: 18 - 110 (UniProt: Q07157)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Ser 15 | - | expression tag |
| His 16 | - | expression tag |
| Met 17 | - | expression tag |
| Gly 111 | - | expression tag |
| Gly 112 | - | expression tag |
| Gly 113 | - | expression tag |
| Ser 114 | - | expression tag |
| Ser 115 | - | expression tag |
| Gly 116 | - | expression tag |
| Lys 117 | - | expression tag |
| Asp 118 | - | expression tag |
| Tyr 119 | - | expression tag |
| Val 120 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22949.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 664.7 | |
| All* | Total formula weight | 23614.5 |
