4NXP

Crystal Structure of Free T-cell Lymphoma Invasion and Metastasis-1 PDZ Domain Quadruple Mutant (QM)

Summary for 4NXP

Entry DOI	10.2210/pdb4nxp/pdb
Related	3KZD 3KZE 4GVC 4GVD 4NXQ 4NXR
Descriptor	T-lymphoma invasion and metastasis-inducing protein 1 (2 entities in total)
Functional Keywords	beta barrel fold protein, pdz domain, peptide binding, specificity mutant, scaffold signaling protein for cell adhesion and cell junction, signaling domain, signaling protein
Biological source	Homo sapiens (human)
Cellular location	Cell junction: Q13009
Total number of polymer chains	1
Total formula weight	10192.40
Authors	Liu, X.,Speckhard, D.C.,Shepherd, T.R.,Hengel, S.R.,Fuentes, E.J. (deposition date: 2013-12-09, release date: 2015-05-13, Last modification date: 2023-09-20)
Primary citation	Liu, X.,Speckhard, D.C.,Shepherd, T.R.,Sun, Y.J.,Hengel, S.R.,Yu, L.,Fowler, C.A.,Gakhar, L.,Fuentes, E.J. Distinct Roles for Conformational Dynamics in Protein-Ligand Interactions. Structure, 24:2053-2066, 2016 Cited by PubMed: 27998539 DOI: 10.1016/j.str.2016.08.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation