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4GVD

Crystal Structure of T-cell Lymphoma Invasion and Metastasis-1 PDZ in complex with Syndecan1 Peptide

Summary for 4GVD
Entry DOI10.2210/pdb4gvd/pdb
Related3KZD 3KZE 4GVC
DescriptorT-lymphoma invasion and metastasis-inducing protein 1, Syndecan-1, CHLORIDE ION, ... (6 entities in total)
Functional Keywordsconformational change during phosphorylation, different binding pocket from phosphorylated sydencan1, scaffold signaling protein for cell adhesion and cell junction, sydencan1 n-terminal thr dansylation, signaling protein
Biological sourceHomo sapiens (human)
More
Cellular locationCell junction: Q13009
Membrane; Single-pass type I membrane protein: P18827
Total number of polymer chains4
Total formula weight22995.99
Authors
Liu, X.,Shepherd, T.R.,Murray, A.M.,Xu, Z.,Fuentes, E.J. (deposition date: 2012-08-30, release date: 2013-03-13, Last modification date: 2023-09-13)
Primary citationLiu, X.,Shepherd, T.R.,Murray, A.M.,Xu, Z.,Fuentes, E.J.
The structure of the Tiam1 PDZ domain/ phospho-syndecan1 complex reveals a ligand conformation that modulates protein dynamics.
Structure, 21:342-354, 2013
Cited by
PubMed: 23395182
DOI: 10.1016/j.str.2013.01.004
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.85 Å)
Structure validation

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