4NNL
Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide
Summary for 4NNL
| Entry DOI | 10.2210/pdb4nnl/pdb |
| Related | 3SFJ 4NNM |
| Descriptor | Tax1-binding protein 3, TIP-1 PDZ domain (3 entities in total) |
| Functional Keywords | tax-interacting protein-1, tip-1, pdz, pdz-peptide, protein binding |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: O14907 |
| Total number of polymer chains | 4 |
| Total formula weight | 25164.55 |
| Authors | Amacher, J.F.,Madden, D.R. (deposition date: 2013-11-18, release date: 2015-01-21, Last modification date: 2023-09-20) |
| Primary citation | Cushing, P.R.,Amacher, J.F.,Vouilleme, L.,Culatti, S.,Deng, B.,Gerber, S.A.,Boisguerin, P.,Madden, D.R. A CAL Inhibitor with Single-PDZ Specificity Rescues deltaF508-CFTR To be Published, |
| Experimental method | X-RAY DIFFRACTION (1.5 Å) |
Structure validation
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