8TJR
 
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody HERH-a.01 Heavy Chain, ... | | Authors: | Morano, N.C, Hoyt, F, Hansen, B, Fischer, E, Shapiro, L. | | Deposit date: | 2023-07-24 | | Release date: | 2024-07-31 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB
To Be Published
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8TJS
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8TNU
 | | Cryo-EM structure of TRNM-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Roark, R.S, Morano, N.C, Shapiro, L.S, Kwong, P.D. | | Deposit date: | 2023-08-02 | | Release date: | 2024-08-07 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.36 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 2024
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8TQ1
 | | HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Bovine Bess4 Fab heavy chain, ... | | Authors: | Ozorowski, G, Lee, W.H, Ward, A.B. | | Deposit date: | 2023-08-06 | | Release date: | 2024-08-07 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Plos Pathog., 20, 2024
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8TOP
 | | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 BG505 DS-SOSIP glycoprotein gp41, ... | | Authors: | Zhou, T, Morano, N.C, Roark, R.S, Kwong, P.D. | | Deposit date: | 2023-08-03 | | Release date: | 2024-08-07 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.52 Å) | | Cite: | Cryo-EM structure of HIV-1 Env BG505 DS-SOSIP in complex with antibody GPZ6-b.01 targeting the fusion peptide
To Be Published
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8TO7
 | | Cryo-EM structure of HERH-b*01 Fab in complex with HIV-1 Env trimer BG505.DS SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HERH-b*01 heavy chain, ... | | Authors: | Roark, R.S, Hoyt, F, Hansen, B, Fischer, E, Shapiro, L.S, Kwong, P.D. | | Deposit date: | 2023-08-03 | | Release date: | 2024-08-07 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.39 Å) | | Cite: | Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques.
Cell, 2024
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8TOX
 | | Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | Authors: | Wang, S, Kwong, P.D. | | Deposit date: | 2023-08-04 | | Release date: | 2024-08-14 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (2.3 Å) | | Cite: | Cryo-EM structure of BG505 Env mutant A517E in complex with antibody ACS202 Fab
To Be Published
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6OZ4
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8TKC
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-b.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-25 | | Release date: | 2024-08-28 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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8TGW
 | | Cryo-EM structure of 1059 SOSIP trimer purified via Galanthus nivalis lectin chromatography | | Descriptor: | 1059 SOSIP Surface protein gp120, 1059 SOSIP Transmembrane protein gp41, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Parsons, R.J, Pothula, K, Acharya, P. | | Deposit date: | 2023-07-13 | | Release date: | 2024-08-28 | | Last modified: | 2024-10-09 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies.
Nat Commun, 15, 2024
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8TL2
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-c.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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8TL4
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-e.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2024-10-23 | | Method: | ELECTRON MICROSCOPY (3.2 Å) | | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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8TGU
 | | Cryo-EM structure of BG505 SOSIP trimer purified via Galanthus nivalis lectin chromatography | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HIV-1 Envelope glycoprotein BG505 SOSIP, ... | | Authors: | Parsons, R.J, Pothula, K, Acharya, P. | | Deposit date: | 2023-07-13 | | Release date: | 2024-08-28 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies.
Nat Commun, 15, 2024
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8TL3
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO DJ85-d.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP glycoprotein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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8TL5
 | | CRYO-EM STRUCTURE OF HIV-1 BG505DS-SOSIP.664 ENV TRIMER BOUND TO HERH-c.01 FAB | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 DS-SOSIP Surface protein gp120, ... | | Authors: | Pletnev, S, Hoyt, F, Fischer, E, Kwong, P. | | Deposit date: | 2023-07-26 | | Release date: | 2024-08-28 | | Last modified: | 2024-10-16 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Broad and potent HIV-1 neutralization in fusion peptide-primed SHIV-boosted macaques.
To Be Published
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6OZC
 | | BG505 SOSIP.664 with 2G12 Fab2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2G12 Fab Heavy chain, ... | | Authors: | Cottrell, C.A, Ward, A.B. | | Deposit date: | 2019-05-15 | | Release date: | 2020-05-20 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.79 Å) | | Cite: | Networks of HIV-1 Envelope Glycans Maintain Antibody Epitopes in the Face of Glycan Additions and Deletions.
Structure, 28, 2020
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6ORO
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab874NHP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab874NHP antibody Fab heavy chain, ... | | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | Deposit date: | 2019-04-30 | | Release date: | 2019-06-12 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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6ORQ
 | | Modified BG505 SOSIP-based immunogen RC1 in complex with the elicited V3-glycan patch antibody Ab275MUR | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ab275MUR antibody Fab heavy chain, ... | | Authors: | Abernathy, M.E, Gristick, H.B, Bjorkman, P.J. | | Deposit date: | 2019-04-30 | | Release date: | 2019-06-12 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques.
Nature, 570, 2019
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6V0R
 | | BG505 SOSIP.664 Trimer | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Nogal, B, Cottrell, C.A, Ward, A.B. | | Deposit date: | 2019-11-19 | | Release date: | 2020-04-01 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3.87 Å) | | Cite: | Mapping Polyclonal Antibody Responses in Non-human Primates Vaccinated with HIV Env Trimer Subunit Vaccines.
Cell Rep, 30, 2020
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6V6W
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6P6F
 | | BG505 SOSIP-I53-50NP | | Descriptor: | I53-50A.1NT1, I53-50B.4PT1 | | Authors: | Berndsen, Z.T, Ward, A.B. | | Deposit date: | 2019-06-03 | | Release date: | 2019-06-19 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (4.5 Å) | | Cite: | Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle.
Nat Commun, 10, 2019
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6OPA
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6VI0
 | | Cryo-EM structure of VRC01.23 in complex with HIV-1 Env BG505 DS.SOSIP | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BG505 gp120, ... | | Authors: | Gorman, J, Kwong, P.D. | | Deposit date: | 2020-01-10 | | Release date: | 2021-01-13 | | Last modified: | 2024-11-06 | | Method: | ELECTRON MICROSCOPY (3.43 Å) | | Cite: | A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention.
Mabs, 13
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6P65
 | | HIV Env 16055 NFL TD 2CC+ in complex with antibody 1C2 fragment antigen binding | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Ozorowski, G, Torres, J.L, Ward, A.B. | | Deposit date: | 2019-05-31 | | Release date: | 2019-11-20 | | Last modified: | 2024-11-13 | | Method: | ELECTRON MICROSCOPY (3.94 Å) | | Cite: | Vaccination with Glycan-Modified HIV NFL Envelope Trimer-Liposomes Elicits Broadly Neutralizing Antibodies to Multiple Sites of Vulnerability.
Immunity, 51, 2019
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6VPX
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