8TGU
Cryo-EM structure of BG505 SOSIP trimer purified via Galanthus nivalis lectin chromatography
Summary for 8TGU
Entry DOI | 10.2210/pdb8tgu/pdb |
EMDB information | 41244 |
Descriptor | HIV-1 Envelope glycoprotein BG505 SOSIP, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | hiv-1, glycoprotein, lectin, trimer, viral protein |
Biological source | Human immunodeficiency virus 1 |
Total number of polymer chains | 3 |
Total formula weight | 233006.49 |
Authors | Parsons, R.J.,Pothula, K.,Acharya, P. (deposition date: 2023-07-13, release date: 2024-08-28, Last modification date: 2024-09-04) |
Primary citation | Parthasarathy, D.,Pothula, K.R.,Ratnapriya, S.,Cervera Benet, H.,Parsons, R.,Huang, X.,Sammour, S.,Janowska, K.,Harris, M.,Sodroski, J.,Acharya, P.,Herschhorn, A. Conformational flexibility of HIV-1 envelope glycoproteins modulates transmitted/founder sensitivity to broadly neutralizing antibodies. Nat Commun, 15:7334-7334, 2024 Cited by PubMed: 39187497DOI: 10.1038/s41467-024-51656-4 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.8 Å) |
Structure validation
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