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8TQ1

HIV-1 BG505 Env SOSIP in complex with bovine Fab Bess4 and non-human primate Fab RM20A3

Summary for 8TQ1
Entry DOI10.2210/pdb8tq1/pdb
EMDB information41498
DescriptorHIV-1 Envelope Glycoprotein BG505 SOSIP.664 gp120, Transmembrane protein gp41, NHP RM20A3 Fab heavy chain, ... (9 entities in total)
Functional Keywordssosip, apex, broadly neutralizing antibody, env, hiv-1, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains13
Total formula weight340440.98
Authors
Ozorowski, G.,Lee, W.H.,Ward, A.B. (deposition date: 2023-08-06, release date: 2024-08-07)
Primary citationAltman, P.,Ozorowski, G.
Immunization of cows with HIV Envelope trimers generates broadly neutralizing antibodies to the V2-apex as well as the CD4 binding site from the ultra-long CDRH3 repertoire
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.3 Å)
Structure validation

223532

PDB entries from 2024-08-07

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