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8TM2
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Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8TM1
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Antibody N3-1 bound to RBDs in the up and down conformations
Descriptor: N3-1 Fab heavy chain, N3-1 Fab light chain, Spike glycoprotein
Authors:Hsieh, C.-L, McLellan, J.S.
Deposit date:2023-07-27
Release date:2024-01-17
Method:ELECTRON MICROSCOPY (2.79 Å)
Cite:SARS-COV-2 Omicron variants conformationally escape a rare quaternary antibody binding mode.
Commun Biol, 6, 2023
8TM0
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Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class I polypeptide-related sequence A, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (3.83 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8TLZ
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Preclinical Characterization of Pan-NKG2D Ligand-Binding NKG2D Receptor Decoys
Descriptor: (2S)-2-hydroxybutanedioic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:Rupert, P.B, Strong, R.
Deposit date:2023-07-27
Release date:2024-04-17
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Preclinical characterization of Pan-NKG2D ligand-binding NKG2D receptor decoys.
Heliyon, 10, 2024
8TLY
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BU of 8tly by Molmil
Human ASCC1 Phosphodiesterase/Ligase Domain
Descriptor: Activating signal cointegrator 1 complex subunit 1
Authors:Tsutakawa, S.E, Tainer, J.A, Arvai, A.S, Thapar, R.
Deposit date:2023-07-27
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:ASCC1 structures and bioinformatics reveal a novel helix-clasp-helix RNA-binding motif linked to a two-histidine phosphodiesterase.
J.Biol.Chem., 300, 2024
8TLX
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Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 21a
Descriptor: GLYCEROL, MBP and AF9 AHD fusion protein 3AQA, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Yang, Y, Nikolovska-Coleska, Z.
Deposit date:2023-07-27
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.097 Å)
Cite:Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024
8TLW
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Crystal structure of MBP and AF9 AHD fusion protein 3AQA in complex with peptidomimetic inhibitor 28
Descriptor: MBP and AF9 AHD fusion protein 3AQA, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, peptidomimetic inhibitor 28
Authors:Yang, Y, Nikolovska-Coleska, Z.
Deposit date:2023-07-27
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.106 Å)
Cite:Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024
8TLV
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BU of 8tlv by Molmil
Crystal structure of MBP and AF9 AHD fusion protein 4AQK in complex with peptidomimetic inhibitor 28
Descriptor: GLUTATHIONE, MBP and AF9 AHD fusion protein 4AQK, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ...
Authors:Yang, Y, Nikolovska-Coleska, Z.
Deposit date:2023-07-27
Release date:2024-05-29
Method:X-RAY DIFFRACTION (2.659 Å)
Cite:Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
Protein Sci., 33, 2024
8TLU
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BU of 8tlu by Molmil
E. coli MraY mutant-T23P
Descriptor: Phospho-N-acetylmuramoyl-pentapeptide-transferase
Authors:Orta, A.K, Li, Y.E, Clemons, W.M.
Deposit date:2023-07-27
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.8 Å)
Cite:Synthesis of lipid-linked precursors of the bacterial cell wall is governed by a feedback control mechanism in Pseudomonas aeruginosa.
Nat Microbiol, 9, 2024
8TLT
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BU of 8tlt by Molmil
Cryo-EM structure of Rev1(deltaN)-Polzeta-DNA-dCTP complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*TP*AP*AP*TP*GP*GP*TP*AP*GP*GP*GP*GP*AP*GP*GP*GP*AP*AP*T)-3'), ...
Authors:Malik, R, Aggarwal, A.K.
Deposit date:2023-07-27
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.85 Å)
Cite:Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 2024
8TLS
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BU of 8tls by Molmil
Crystal structure of Shewanella benthica Group 1 truncated hemoglobin C51S C71S Y108A variant
Descriptor: CYANIDE ION, Group 1 truncated hemoglobin, PROTOPORPHYRIN IX CONTAINING FE
Authors:Schultz, T.D, Martinez, J.E, Siegler, M.A, Schlessman, J.L, Lecomte, J.T.J.
Deposit date:2023-07-27
Release date:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of Shewanella benthica Group 1 truncated hemoglobin C51S C71S Y108A variant
To Be Published
8TLQ
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BU of 8tlq by Molmil
Cryo-EM structure of the Rev1-Polzeta-DNA-dCTP complex
Descriptor: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (30-MER), ...
Authors:Malik, R, Aggarwal, A.K.
Deposit date:2023-07-27
Release date:2024-05-15
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.53 Å)
Cite:Cryo-EM structure of the Rev1-Pol zeta holocomplex reveals the mechanism of their cooperativity in translesion DNA synthesis.
Nat.Struct.Mol.Biol., 2024
8TLN
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BU of 8tln by Molmil
STRUCTURAL COMPARISON SUGGESTS THAT THERMOLYSIN AND RELATED NEUTRAL PROTEASES UNDERGO HINGE-BENDING MOTION DURING CATALYSIS
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, LYSINE, ...
Authors:Tronrud, D, Matthews, B.W.
Deposit date:1993-09-01
Release date:1994-04-30
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural comparison suggests that thermolysin and related neutral proteases undergo hinge-bending motion during catalysis.
Biochemistry, 31, 1992
8TLM
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BU of 8tlm by Molmil
Structure of a class A GPCR/Fab complex
Descriptor: C-C chemokine receptor type 8, Green fluorescent protein fusion, Fab heavy chain, ...
Authors:Sun, D, Johnson, M, Masureel, M.
Deposit date:2023-07-27
Release date:2023-12-20
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8.
Nat Commun, 14, 2023
8TLI
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BU of 8tli by Molmil
THERMOLYSIN (100% ISOPROPANOL SOAKED CRYSTALS)
Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, ISOPROPYL ALCOHOL, ...
Authors:English, A.C, Done, S.H, Groom, C.R, Hubbard, R.E.
Deposit date:1998-10-30
Release date:2000-03-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Locating interaction sites on proteins: the crystal structure of thermolysin soaked in 2% to 100% isopropanol.
Proteins, 37, 1999
8TLD
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BU of 8tld by Molmil
Structure of the IL-5 Signaling Complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor common subunit beta, Interleukin-5, ...
Authors:Caveney, N.A, Garcia, K.C.
Deposit date:2023-07-26
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Organizing structural principles of common beta family signaling
To Be Published
8TLC
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BU of 8tlc by Molmil
Human mitochondrial serine hydroxymethyltransferase (SHMT2) in complex with PLP, glycine and tri-glutamate AGF347 inhibitor
Descriptor: N-{4-[4-(2-amino-4-oxo-1,4-dihydro-5H-pyrrolo[3,2-d]pyrimidin-5-yl)butyl]-2-fluorobenzoyl}-D-gamma-glutamyl-L-gamma-glutamyl-D-glutamic acid, Serine hydroxymethyltransferase, mitochondrial
Authors:Katinas, J.M, Dann III, C.E.
Deposit date:2023-07-26
Release date:2024-02-21
Method:X-RAY DIFFRACTION (2.72 Å)
Cite:Structural Characterization of 5-Substituted Pyrrolo[3,2- d ]pyrimidine Antifolate Inhibitors in Complex with Human Serine Hydroxymethyl Transferase 2.
Biochemistry, 2024
8TLA
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BU of 8tla by Molmil
Human Type 3 IP3 Receptor - Higher-Order Inhibited State - Symmetry Mate 1
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
Authors:Paknejad, N, Sapuru, V, Hite, R.K.
Deposit date:2023-07-26
Release date:2023-11-08
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural titration reveals Ca 2+ -dependent conformational landscape of the IP 3 receptor.
Nat Commun, 14, 2023
8TL9
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BU of 8tl9 by Molmil
Human Type 3 IP3 Receptor - Resting State (+IP3/ATP)
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE, ...
Authors:Paknejad, N, Sapuru, V, Hite, R.K.
Deposit date:2023-07-26
Release date:2023-11-08
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Structural titration reveals Ca 2+ -dependent conformational landscape of the IP 3 receptor.
Nat Commun, 14, 2023
8TL8
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BU of 8tl8 by Molmil
Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid
Descriptor: GLYCOCHOLIC ACID, Protein sigma-NS
Authors:Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N.
Deposit date:2023-07-26
Release date:2024-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories.
Nat Commun, 15, 2024
8TL7
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BU of 8tl7 by Molmil
CryoEM Structure of a Computationally Designed T3 Tetrahedral Nanocage
Descriptor: Computationally designed protein
Authors:Weidle, C, Borst, A.J.
Deposit date:2023-07-26
Release date:2024-03-13
Last modified:2024-04-10
Method:ELECTRON MICROSCOPY (4.05 Å)
Cite:Blueprinting extendable nanomaterials with standardized protein blocks.
Nature, 627, 2024
8TL6
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BU of 8tl6 by Molmil
Cryo-EM structure of DDB1deltaB-DDA1-DCAF5
Descriptor: DDB1- and CUL4-associated factor 5, DET1- and DDB1-associated protein 1, DNA damage-binding protein 1
Authors:Yue, H, Hunkeler, M, Roy Burman, S.S, Fischer, E.S.
Deposit date:2023-07-26
Release date:2024-04-03
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (2.63 Å)
Cite:Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.
Nature, 628, 2024
8TL1
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BU of 8tl1 by Molmil
Structure of Orthoreovirus RNA Chaperone SigmaNS N17
Descriptor: GLYCOCHOLIC ACID, Protein sigma-NS
Authors:Prasad, B.V.V, Zhao, B, Hu, L.
Deposit date:2023-07-26
Release date:2024-03-06
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (3.16 Å)
Cite:Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories.
Nat Commun, 15, 2024
8TL0
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Structure of activated SAVED-CHAT filament
Descriptor: CHAT domain-containing protein, RNA (5'-R(*AP*AP*A)-3')
Authors:Bravo, J.P.K, Taylor, D.W.
Deposit date:2023-07-26
Release date:2024-03-06
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Type III-B CRISPR-Cas cascade of proteolytic cleavages.
Science, 383, 2024
8TKZ
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Structure of fission yeast Duf89 protein bound to Co2+ and PO4
Descriptor: CHLORIDE ION, COBALT (II) ION, DI(HYDROXYETHYL)ETHER, ...
Authors:Jacewicz, A, Sanchez, A.M, Shuman, S.
Deposit date:2023-07-26
Release date:2024-06-26
Method:X-RAY DIFFRACTION (2.06 Å)
Cite:Structure of fission yeast Duf89 protein bound to Co2+ and PO4
To Be Published

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PDB entries from 2024-07-17

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