8TLV

Crystal structure of MBP and AF9 AHD fusion protein 4AQK in complex with peptidomimetic inhibitor 28

Summary for 8TLV

Entry DOI	10.2210/pdb8tlv/pdb
Related PRD ID	PRD_900001
Descriptor	MBP and AF9 AHD fusion protein 4AQK, peptidomimetic inhibitor 28, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total)
Functional Keywords	mll fusion super elongation complex (sec) acute lymphoblastic leukemia acute myeloid leukemia, translation
Biological source	Escherichia coli K-12 More
Total number of polymer chains	2
Total formula weight	50371.93
Authors	Yang, Y.,Nikolovska-Coleska, Z. (deposition date: 2023-07-27, release date: 2024-05-29)
Primary citation	Yang, Y.,Ahmad, E.,Premkumar, V.,Liu, A.,Ashikur Rahman, S.M.,Nikolovska-Coleska, Z. Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors. Protein Sci., 33:e5019-e5019, 2024 Cited by PubMed: 38747396 DOI: 10.1002/pro.5019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.659 Å)

Structure validation