8TLM

Structure of a class A GPCR/Fab complex

Summary for 8TLM

Entry DOI	10.2210/pdb8tlm/pdb
EMDB information	41370
Descriptor	Fab heavy chain, Fab light chain, C-C chemokine receptor type 8, Green fluorescent protein fusion (3 entities in total)
Functional Keywords	gpcr fab, structural protein
Biological source	Oryctolagus cuniculus (rabbit) More
Total number of polymer chains	3
Total formula weight	123181.92
Authors	Sun, D.,Johnson, M.,Masureel, M. (deposition date: 2023-07-27, release date: 2023-12-20)
Primary citation	Sun, D.,Sun, Y.,Janezic, E.,Zhou, T.,Johnson, M.,Azumaya, C.,Noreng, S.,Chiu, C.,Seki, A.,Arenzana, T.L.,Nicoludis, J.M.,Shi, Y.,Wang, B.,Ho, H.,Joshi, P.,Tam, C.,Payandeh, J.,Comps-Agrar, L.,Wang, J.,Rutz, S.,Koerber, J.T.,Masureel, M. Structural basis of antibody inhibition and chemokine activation of the human CC chemokine receptor 8. Nat Commun, 14:7940-7940, 2023 Cited by PubMed: 38040762 DOI: 10.1038/s41467-023-43601-8 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation