8TLM
Structure of a class A GPCR/Fab complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Fab heavy chain | polymer | 225 | 23775.5 | 1 | Oryctolagus cuniculus (rabbit) | ||
| 2 | B (B) | Fab light chain | polymer | 217 | 23402.9 | 1 | Oryctolagus cuniculus (rabbit) | ||
| 3 | C (C) | C-C chemokine receptor type 8, Green fluorescent protein fusion | polymer | 671 | 76003.5 | 1 | UniProt (P51685) UniProt (P42212) Pfam (PF00001) Pfam (PF01353) | Homo sapiens (human) |
Sequence modifications
C: 1 - 355 (UniProt: P51685)
C: 369 - 605 (UniProt: P42212)
| PDB | External Database | Details |
|---|---|---|
| Met -34 | - | initiating methionine |
| Lys -33 | - | expression tag |
| Thr -32 | - | expression tag |
| Ile -31 | - | expression tag |
| Ile -30 | - | expression tag |
| Ala -29 | - | expression tag |
| Leu -28 | - | expression tag |
| Ser -27 | - | expression tag |
| Tyr -26 | - | expression tag |
| Ile -25 | - | expression tag |
| Phe -24 | - | expression tag |
| Cys -23 | - | expression tag |
| Leu -22 | - | expression tag |
| Val -21 | - | expression tag |
| Phe -20 | - | expression tag |
| Ala -19 | - | expression tag |
| Asp -18 | - | expression tag |
| Tyr -17 | - | expression tag |
| Lys -16 | - | expression tag |
| Asp -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Asp -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Lys -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Glu -8 | - | expression tag |
| Asn -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Tyr -5 | - | expression tag |
| Phe -4 | - | expression tag |
| Gln -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Gly 356 | - | linker |
| Asn 357 | - | linker |
| Ser 358 | - | linker |
| Leu 359 | - | linker |
| Glu 360 | - | linker |
| Val 361 | - | linker |
| Leu 362 | - | linker |
| Phe 363 | - | linker |
| Gln 364 | - | linker |
| Gly 365 | - | linker |
| Pro 366 | - | linker |
| Met 367 | - | linker |
| Val 368 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Leu 413 | Phe 46 | conflict |
| Leu 431 | Phe 64 | conflict |
| Gly 432 | Ser 65 | conflict |
| Leu 435 | Val 68 | conflict |
| Ala 439 | Ser 72 | conflict |
| Thr 520 | Met 153 | conflict |
| Ala 530 | Val 163 | conflict |
| Gly 542 | Ser 175 | conflict |
| Tyr 570 | Thr 203 | conflict |
| Lys 573 | Ala 206 | conflict |
| Leu 598 | His 231 | conflict |
| Gly 606 | - | expression tag |
| Ser 607 | - | expression tag |
| Ala 608 | - | expression tag |
| Trp 609 | - | expression tag |
| Ser 610 | - | expression tag |
| His 611 | - | expression tag |
| Pro 612 | - | expression tag |
| Gln 613 | - | expression tag |
| Phe 614 | - | expression tag |
| Glu 615 | - | expression tag |
| Lys 616 | - | expression tag |
| Gly 617 | - | expression tag |
| Gly 618 | - | expression tag |
| Gly 619 | - | expression tag |
| Ser 620 | - | expression tag |
| Gly 621 | - | expression tag |
| Gly 622 | - | expression tag |
| Gly 623 | - | expression tag |
| Ser 624 | - | expression tag |
| Gly 625 | - | expression tag |
| Gly 626 | - | expression tag |
| Ser 627 | - | expression tag |
| Ala 628 | - | expression tag |
| Trp 629 | - | expression tag |
| Ser 630 | - | expression tag |
| His 631 | - | expression tag |
| Pro 632 | - | expression tag |
| Gln 633 | - | expression tag |
| Phe 634 | - | expression tag |
| Glu 635 | - | expression tag |
| Lys 636 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 123181.9 | |
| All* | Total formula weight | 123181.9 |
