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4TQO
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BU of 4tqo by Molmil
The crystal structure of methanol dehydrogenase from Methylococcus capsulatus (Bath)
Descriptor: CALCIUM ION, Methanol dehydrogenase protein, large subunit, ...
Authors:Culpepper, M.A, Rosenzweig, A.C.
Deposit date:2014-06-11
Release date:2014-09-24
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structure and Protein-Protein Interactions of Methanol Dehydrogenase from Methylococcus capsulatus (Bath).
Biochemistry, 53, 2014
6T8F
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BU of 6t8f by Molmil
Crystal structure of mutant xylose isomerase (V270A/A273G) from Piromyces E2 grown in yeast, in complex with xylose
Descriptor: CALCIUM ION, D-xylose, SULFATE ION, ...
Authors:Rozeboom, H.J, Janssen, D.B.
Deposit date:2019-10-24
Release date:2020-01-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure-based directed evolution improves S. cerevisiae growth on xylose by influencing in vivo enzyme performance.
Biotechnol Biofuels, 13, 2020
4ZER
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BU of 4zer by Molmil
Crystal structure of the Onc112 antimicrobial peptide bound to the Thermus thermophilus 70S ribosome
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 16s ribosomal RNA, 23s ribosomal RNA, ...
Authors:Seefeldt, A.C, Nguyen, F, Antunes, S, Perebaskine, N, Graf, M, Arenz, S, Inampudi, K.K, Douat, C, Guichard, G, Wilson, D.N, Innis, C.A.
Deposit date:2015-04-20
Release date:2015-05-20
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complex.
Nat.Struct.Mol.Biol., 22, 2015
6BZ5
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BU of 6bz5 by Molmil
Structure and mechanism of salicylate hydroxylase from Pseudomonas putida G7
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, IODIDE ION, ...
Authors:Nagem, R.A.P, Costa, D.M.A.
Deposit date:2017-12-22
Release date:2018-12-26
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.006 Å)
Cite:Catalytic mechanism for the conversion of salicylate into catechol by the flavin-dependent monooxygenase salicylate hydroxylase.
Int.J.Biol.Macromol., 129, 2019
5OKM
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BU of 5okm by Molmil
Crystal structure of human SHIP2 Phosphatase-C2
Descriptor: 1,2-ETHANEDIOL, 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, NITRATE ION, ...
Authors:Le Coq, J, Lietha, D.
Deposit date:2017-07-25
Release date:2017-08-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.96 Å)
Cite:Structural basis for interdomain communication in SHIP2 providing high phosphatase activity.
Elife, 6, 2017
4TUE
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BU of 4tue by Molmil
Crystal structure of ASL-SufJ bound to Codon ACC-U on the Ribosome
Descriptor: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
Authors:Fagan, C.E, Dunham, C.M.
Deposit date:2014-06-24
Release date:2015-05-13
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural insights into translational recoding by frameshift suppressor tRNASufJ.
Rna, 20, 2014
6JR4
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BU of 6jr4 by Molmil
Crystal structure of a NIR-emitting DNA-stabilized Ag16 nanocluster
Descriptor: CALCIUM ION, DNA (5'-D(*CP*AP*CP*CP*TP*AP*GP*CP*GP*A)-3'), SILVER ION
Authors:Kondo, J, Cerretani, C, Kanazawa, H, Vosch, T.
Deposit date:2019-04-02
Release date:2019-08-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Crystal structure of a NIR-Emitting DNA-Stabilized Ag16Nanocluster.
Angew.Chem.Int.Ed.Engl., 58, 2019
5EJD
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BU of 5ejd by Molmil
The crystal structure of holo T3CT
Descriptor: 4'-PHOSPHOPANTETHEINE, GLYCEROL, TqaA
Authors:Zhang, J.R, Tang, Y, Zhou, J.H.
Deposit date:2015-11-01
Release date:2016-10-19
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.49 Å)
Cite:Structural basis of nonribosomal peptide macrocyclization in fungi
Nat.Chem.Biol., 12, 2016
6JKD
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BU of 6jkd by Molmil
Crystal structure of tetrameric PepTSo2 in I4 space group
Descriptor: Proton:oligopeptide symporter POT family
Authors:Nagamura, R, Fukuda, M, Ishitani, R, Nureki, O.
Deposit date:2019-02-28
Release date:2019-05-15
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Structural basis for oligomerization of the prokaryotic peptide transporter PepTSo2.
Acta Crystallogr.,Sect.F, 75, 2019
6JCZ
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BU of 6jcz by Molmil
Cryo-EM Structure of Sulfolobus solfataricus ketol-acid reductoisomerase (Sso-KARI) in complex with Mg2+, NADPH, and CPD at pH7.5
Descriptor: MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative ketol-acid reductoisomerase 2, ...
Authors:Chen, C.Y, Chang, Y.C, Lin, K.F, Huang, C.H, Lin, B.L, Ko, T.P, Hsieh, D.L, Tsai, M.D.
Deposit date:2019-01-30
Release date:2019-04-17
Last modified:2019-05-01
Method:ELECTRON MICROSCOPY (3.35 Å)
Cite:Use of Cryo-EM To Uncover Structural Bases of pH Effect and Cofactor Bispecificity of Ketol-Acid Reductoisomerase.
J. Am. Chem. Soc., 141, 2019
5ELB
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BU of 5elb by Molmil
Cholera toxin classical B-pentamer in complex with Lewis-y
Descriptor: BICINE, CALCIUM ION, Cholera enterotoxin B subunit, ...
Authors:Heggelund, J.E, Burschowsky, D, Krengel, U.
Deposit date:2015-11-04
Release date:2016-03-30
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.08 Å)
Cite:High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.
Plos Pathog., 12, 2016
5O31
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BU of 5o31 by Molmil
Mitochondrial complex I in the deactive state
Descriptor: Acyl carrier protein, mitochondrial, FE2/S2 (INORGANIC) CLUSTER, ...
Authors:Blaza, J.N, Vinothkumar, K.R, Hirst, J.
Deposit date:2017-05-23
Release date:2018-01-17
Last modified:2019-10-23
Method:ELECTRON MICROSCOPY (4.13 Å)
Cite:Structure of the Deactive State of Mammalian Respiratory Complex I.
Structure, 26, 2018
5O64
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BU of 5o64 by Molmil
From macrocrystals to microcrystals: a strategy for membrane protein serial crystallography
Descriptor: 15-cis-1,2-dihydroneurosporene, BACTERIOCHLOROPHYLL B, BACTERIOPHEOPHYTIN B, ...
Authors:Dods, R, Baath, P, Branden, G, Neutze, R.
Deposit date:2017-06-05
Release date:2017-08-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:From Macrocrystals to Microcrystals: A Strategy for Membrane Protein Serial Crystallography.
Structure, 25, 2017
6C4J
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BU of 6c4j by Molmil
Ligand bound full length hUGDH with A104L substitution
Descriptor: CHLORIDE ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-1,2-PROPANEDIOL, ...
Authors:Beattie, N.R, Pioso, B.J, Wood, Z.A, Sidlo, A.M.
Deposit date:2018-01-12
Release date:2018-05-16
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.53 Å)
Cite:Hysteresis and Allostery in Human UDP-Glucose Dehydrogenase Require a Flexible Protein Core.
Biochemistry, 57, 2018
5ERP
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BU of 5erp by Molmil
Crystal structure of human Desmocollin-2 ectodomain fragment EC2-5
Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Harrison, O.J, Brasch, J, Shapiro, L.
Deposit date:2015-11-14
Release date:2016-06-15
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of adhesive binding by desmocollins and desmogleins.
Proc.Natl.Acad.Sci.USA, 113, 2016
5EOM
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BU of 5eom by Molmil
Structure of full-length human MAB21L1 with bound CTP
Descriptor: CITRIC ACID, CYTIDINE-5'-TRIPHOSPHATE, Protein mab-21-like 1, ...
Authors:de Oliveira Mann, C.C, Witte, G, Hopfner, K.-P.
Deposit date:2015-11-10
Release date:2016-06-01
Last modified:2024-05-01
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Structural and biochemical characterization of the cell fate determining nucleotidyltransferase fold protein MAB21L1.
Sci Rep, 6, 2016
6BMZ
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BU of 6bmz by Molmil
Influenza A M2 transmembrane domain bound to a spiroadamantane inhibitor
Descriptor: (1r,1'S,3'S,5'S,7'S)-spiro[cyclohexane-1,2'-tricyclo[3.3.1.1~3,7~]decan]-4-amine, CHLORIDE ION, Matrix protein 2
Authors:Thomaston, J.L, DeGrado, W.F.
Deposit date:2017-11-15
Release date:2018-09-19
Last modified:2024-10-30
Method:X-RAY DIFFRACTION (2.634 Å)
Cite:Inhibitors of the M2 Proton Channel Engage and Disrupt Transmembrane Networks of Hydrogen-Bonded Waters.
J. Am. Chem. Soc., 140, 2018
5EEV
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BU of 5eev by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 3.88 MGy
Descriptor: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
Authors:Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
Deposit date:2015-10-23
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016
5ND8
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BU of 5nd8 by Molmil
Hibernating ribosome from Staphylococcus aureus (Unrotated state)
Descriptor: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
Authors:Khusainov, I, Vicens, Q, Ayupov, R, Usachev, K, Myasnikov, A, Simonetti, A, Validov, S, Kieffer, B, Yusupova, G, Yusupov, M, Hashem, Y.
Deposit date:2017-03-07
Release date:2017-06-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structures and dynamics of hibernating ribosomes from Staphylococcus aureus mediated by intermolecular interactions of HPF.
EMBO J., 36, 2017
6TB9
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BU of 6tb9 by Molmil
Capsid of native GTA particle computed with C5 symmetry
Descriptor: Head spike base Rcc01079, Head spike fiber Rcc01080, Major capsid protein Rcc01687
Authors:Bardy, P, Fuzik, T, Hrebik, D, Pantucek, R, Beatty, J.T, Plevka, P.
Deposit date:2019-11-01
Release date:2020-07-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.56 Å)
Cite:Structure and mechanism of DNA delivery of a gene transfer agent.
Nat Commun, 11, 2020
5NDW
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BU of 5ndw by Molmil
Crystal structure of aminoglycoside TC007 bound to the yeast 80S ribosome
Descriptor: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
Authors:Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G.
Deposit date:2017-03-09
Release date:2017-12-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (3.7 Å)
Cite:Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
4Z3S
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BU of 4z3s by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with antibiotic A201A, mRNA and three tRNAs in the A, P and E sites at 2.65A resolution
Descriptor: 16S Ribosomal RNA, 23S Ribosomal RNA, 3'-deoxy-3'-{[(2E)-3-(4-{[(4Z)-6-O-(6-deoxy-3,4-di-O-methyl-alpha-D-mannopyranosyl)-5-O-methyl-alpha-D-threo-hex-4-enofuranosyl]oxy}phenyl)-2-methylprop-2-enoyl]amino}-N,N-dimethyladenosine, ...
Authors:Polikanov, Y.S, Starosta, A.L, Juette, M.F, Altman, R.B, Terry, D.S, Lu, W, Burnett, B.J, Dinos, G, Reynolds, K, Blanchard, S.C, Steitz, T.A, Wilson, D.N.
Deposit date:2015-03-31
Release date:2015-06-03
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.
Mol.Cell, 58, 2015
6JO0
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BU of 6jo0 by Molmil
Crystal structure of the DTS-motif rhodopsin from Phaeocystis globosa virus 12T
Descriptor: (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, DECANE, DODECANE, ...
Authors:Hosaka, T, Kimura-Someya, T, Shirouzu, M.
Deposit date:2019-03-19
Release date:2019-10-02
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (1.651 Å)
Cite:A distinct lineage of giant viruses brings a rhodopsin photosystem to unicellular marine predators.
Proc.Natl.Acad.Sci.USA, 116, 2019
5FGD
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BU of 5fgd by Molmil
Yeast 20S proteasome beta5-H(-2)L-T1A double mutant in complex with Carfilzomib
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, MAGNESIUM ION, ...
Authors:Huber, E.M, Groll, M.
Deposit date:2015-12-20
Release date:2016-03-23
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Nat Commun, 7, 2016
5EF3
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BU of 5ef3 by Molmil
RADIATION DAMAGE TO THE TRAP-RNA COMPLEX: DOSE (DWD) 25.0 MGy
Descriptor: (GAGUU)10GAG 53-NUCLEOTIDE RNA, TRYPTOPHAN, Transcription attenuation protein MtrB
Authors:Bury, C.S, McGeehan, J.E, Garman, E.F, Shevtsov, M.B.
Deposit date:2015-10-23
Release date:2016-05-04
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:RNA protects a nucleoprotein complex against radiation damage.
Acta Crystallogr D Struct Biol, 72, 2016

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