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1B2G
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BU of 1b2g by Molmil
PH AFFECTS GLU B13 SWITCHING AND SULFATE BINDING IN CUBIC INSULIN CRYSTALS (PH 9.00 COORDINATES)
Descriptor: PROTEIN (INSULIN a chain), PROTEIN (INSULIN b chain)
Authors:Diao, J.S, Caspar, D.L.D.
Deposit date:1998-11-26
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic titration of cubic insulin crystals: pH affects GluB13 switching and sulfate binding.
Acta Crystallogr.,Sect.D, 59, 2003
1BQT
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BU of 1bqt by Molmil
THREE-DIMENSIONAL STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR-I (IGF-I) DETERMINED BY 1H-NMR AND DISTANCE GEOMETRY, 6 STRUCTURES
Descriptor: INSULIN-LIKE GROWTH FACTOR-I
Authors:Sato, A, Nishimura, S, Ohkubo, T, Kyogoku, Y, Koyama, S, Kobayashi, M, Yasuda, T, Kobayashi, Y.
Deposit date:1998-08-18
Release date:1999-05-18
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Three-dimensional structure of human insulin-like growth factor-I (IGF-I) determined by 1H-NMR and distance geometry.
Int.J.Pept.Protein Res., 41, 1993
1AI0
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BU of 1ai0 by Molmil
R6 HUMAN INSULIN HEXAMER (NON-SYMMETRIC), NMR, 10 STRUCTURES
Descriptor: PHENOL, R6 INSULIN HEXAMER, ZINC ION
Authors:Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J.
Deposit date:1997-04-30
Release date:1997-11-12
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
1AIY
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BU of 1aiy by Molmil
R6 HUMAN INSULIN HEXAMER (SYMMETRIC), NMR, 10 STRUCTURES
Descriptor: PHENOL, R6 INSULIN HEXAMER, ZINC ION
Authors:Chang, X, Jorgensen, A.M.M, Bardrum, P, Led, J.J.
Deposit date:1997-04-30
Release date:1997-11-12
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structures of the R6 human insulin hexamer.
Biochemistry, 36, 1997
1B2C
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BU of 1b2c by Molmil
PH AFFECTS GLU B13 SWITCHING AND SULFATE BINDING IN CUBIC INSULIN CRYSTALS (PH 6.26 COORDINATES)
Descriptor: PROTEIN (INSULIN A CHAIN), PROTEIN (INSULIN B CHAIN), SULFATE ION
Authors:Diao, J.S, Caspar, D.L.D.
Deposit date:1998-11-26
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic titration of cubic insulin crystals: pH affects GluB13 switching and sulfate binding.
Acta Crystallogr.,Sect.D, 59, 2003
1B2F
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BU of 1b2f by Molmil
PH AFFECTS GLU B13 SWITCHING AND SULFATE BINDING IN CUBIC INSULIN CRYSTALS (PH 6.98 COORDINATES)
Descriptor: PROTEIN (INSULIN A CHAIN), PROTEIN (INSULIN B CHAIN)
Authors:Diao, J.S, Caspar, D.L.D.
Deposit date:1998-11-26
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystallographic titration of cubic insulin crystals: pH affects GluB13 switching and sulfate binding.
Acta Crystallogr.,Sect.D, 59, 2003
1B2B
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BU of 1b2b by Molmil
PH AFFECTS GLU B13 SWITCHING AND SULFATE BINDING IN CUBIC INSULIN CRYSTALS (PH 6.16 COORDINATES)
Descriptor: PROTEIN (INSULIN A CHAIN), PROTEIN (INSULIN B CHAIN), SULFATE ION
Authors:Diao, J.S, Caspar, D.L.D.
Deposit date:1998-11-26
Release date:2003-04-08
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic titration of cubic insulin crystals: pH affects GluB13 switching and sulfate binding.
Acta Crystallogr.,Sect.D, 59, 2003
1CPH
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BU of 1cph by Molmil
CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor: 1,2-DICHLOROETHANE, INSULIN (PH 10), SODIUM ION
Authors:Gursky, O, Badger, J, Li, Y, Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
1BON
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BU of 1bon by Molmil
THREE-DIMENSIONAL STRUCTURE OF BOMBYXIN-II, AN INSULIN-RELATED BRAIN-SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX MORI: COMPARISON WITH INSULIN AND RELAXIN
Descriptor: BOMBYXIN-II,BOMBYXIN A-2, BOMBYXIN-II,BOMBYXIN A-6
Authors:Nagata, K, Hatanaka, H, Kohda, D, Inagaki, F, Structural Proteomics in Europe (SPINE)
Deposit date:1994-07-21
Release date:1995-01-26
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:Three-dimensional solution structure of bombyxin-II an insulin-like peptide of the silkmoth Bombyx mori: structural comparison with insulin and relaxin.
J.Mol.Biol., 253, 1995
1BPH
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BU of 1bph by Molmil
CONFORMATIONAL CHANGES IN CUBIC INSULIN CRYSTALS IN THE PH RANGE 7-11
Descriptor: 1,2-DICHLOROETHANE, INSULIN A CHAIN (PH 9), INSULIN B CHAIN (PH 9), ...
Authors:Gursky, O, Badger, J, Li, Y, Caspar, D.L.D.
Deposit date:1992-10-30
Release date:1993-01-15
Last modified:2017-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:Conformational changes in cubic insulin crystals in the pH range 7-11.
Biophys.J., 63, 1992
2LGB
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BU of 2lgb by Molmil
Modified A22Gly-B31Arg Human Insulin
Descriptor: Insulin A chain, Insulin B chain
Authors:Bocian, W, Kozerski, L.
Deposit date:2011-07-25
Release date:2012-04-11
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Recombinant A22(G)-B31 (R)-human insulin. A22 addition introduces conformational mobility in B chain C-terminus.
J.Biomol.Nmr, 52, 2012
2L1Z
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BU of 2l1z by Molmil
NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures
Descriptor: Insulin A chain, Insulin B chain
Authors:Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A.
Deposit date:2010-08-09
Release date:2011-08-31
Last modified:2020-02-05
Method:SOLUTION NMR
Cite:Chiral Protein Engineering and its Application in G Health
To be Published
2L1Y
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BU of 2l1y by Molmil
NMR Structure of human insulin mutant GLY-B20-D-ALA, GLY-B23-D-ALA PRO-B28-LYS, LYS-B29-PRO, 20 Structures
Descriptor: Insulin A chain, Insulin B chain
Authors:Wan, Z.L, Hua, Q.X, Huang, K, Hu, S.Q, Philips, N.B, Katsoyannis, J.W, Weiss, M.A.
Deposit date:2010-08-09
Release date:2011-08-31
Method:SOLUTION NMR
Cite:Chiral Protein Engineering and its Application in G Health
To be Published
2M2N
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BU of 2m2n by Molmil
Structure of [L-HisB24] insulin analogue at pH 8.0
Descriptor: Insulin A chain, Insulin B chain
Authors:Zakova, L, Veverka, V, Jiracek, J.
Deposit date:2012-12-29
Release date:2013-03-06
Last modified:2013-06-05
Method:SOLUTION NMR
Cite:Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2M2O
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BU of 2m2o by Molmil
Structure of [D-HisB24] insulin analogue at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Zakova, L, Veverka, V, Jiracek, J.
Deposit date:2012-12-29
Release date:2013-03-06
Last modified:2013-06-05
Method:SOLUTION NMR
Cite:Structural integrity of the B24 site in human insulin is important for hormone functionality.
J.Biol.Chem., 288, 2013
2LWZ
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BU of 2lwz by Molmil
NMR Structures of Single-chain Insulin
Descriptor: SINGLE-CHAIN INSULIN
Authors:Weiss, M.A, Yang, Y.
Deposit date:2012-08-09
Release date:2013-08-28
Method:SOLUTION NMR
Cite:Dynamic repair of an amyloidogenic protein: Insulin fibrillation is blocked by tethering a nascent alpha-helix
To be Published
2MLI
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BU of 2mli by Molmil
NMR structure of B25-(alpha, beta)-dehydro-phenylalanine insulin
Descriptor: Insulin
Authors:Yang, Y, Weiss, M.
Deposit date:2014-02-27
Release date:2014-08-20
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Protective hinge in insulin opens to enable its receptor engagement.
Proc.Natl.Acad.Sci.USA, 111, 2014
2M1E
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BU of 2m1e by Molmil
Biosynthetic engineered B28K-B29P human insulin monomer structure in in water solutions.
Descriptor: Insulin
Authors:Bocian, W, Kozerski, L.
Deposit date:2012-11-26
Release date:2013-02-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Biosynthetic engineered B28(K)-B29(P) human insulin monomer structure in water and in water/acetonitrile solutions.
J.Biomol.Nmr, 55, 2013
2N2X
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BU of 2n2x by Molmil
Solution structure of [GlyB24,B27-B29 triazole cross-linked]-insulin analogue at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Veverka, V, Hexnerova, R, Jiracek, J.
Deposit date:2015-05-15
Release date:2016-02-03
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Rational steering of insulin binding specificity by intra-chain chemical crosslinking.
Sci Rep, 6, 2016
2MVD
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BU of 2mvd by Molmil
Solution structure of [GlnB22]-insulin mutant at pH 1.9
Descriptor: Insulin A chain, Insulin B chain
Authors:Hexnerova, R, Krizkova, K, Maletinska, L, Jiracek, J, Brzozowski, A.M, Zakova, L, Veverka, V.
Deposit date:2014-10-02
Release date:2014-12-10
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Structural and Functional Study of the GlnB22-Insulin Mutant Responsible for Maturity-Onset Diabetes of the Young.
Plos One, 9, 2014
2OMG
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BU of 2omg by Molmil
Structure of human insulin cocrystallized with protamine and urea
Descriptor: CHLORIDE ION, FORMAMIDE, Insulin A chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-22
Release date:2007-03-27
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.52 Å)
Cite:Structural characterization of insulin NPH formulations.
EUR.J.PHARM.SCI., 30, 2007
2OLZ
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BU of 2olz by Molmil
Structure of human insulin in presence of thiocyanate at pH 7.0
Descriptor: GLYCEROL, Insulin A, Insulin B, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
2OM0
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BU of 2om0 by Molmil
Structure of human insulin in presence of urea at pH 6.5
Descriptor: CHLORIDE ION, Insulin A chain, Insulin B chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
2OLY
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BU of 2oly by Molmil
Structure of human insulin in presence of urea at pH 7.0
Descriptor: CHLORIDE ION, GLYCEROL, Insulin A chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007
2OM1
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BU of 2om1 by Molmil
Structure of human insulin in presence of thiocyanate at pH 6.5
Descriptor: GLYCEROL, Insulin A chain, Insulin B chain, ...
Authors:Norrman, M, Schluckebier, G.
Deposit date:2007-01-20
Release date:2007-12-04
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Crystallographic characterization of two novel crystal forms of human insulin induced by chaotropic agents and a shift in pH.
Bmc Struct.Biol., 7, 2007

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