8EVP
| Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), Structure I | Descriptor: | 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-20 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EVR
| Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2, GDP, and sordarin, Structure II | Descriptor: | (1S,3S,3aR,4S,4aR,7R,7aR,8aS)-8a-{[(6-deoxy-4-O-methyl-alpha-D-altropyranosyl)oxy]methyl}-4-formyl-7-methyl-3-(propan-2-yl)decahydro-1,4-methano-s-indacene-3a(1H)-carboxylate, 18S rRNA, 25S rRNA, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-20 | Release date: | 2023-09-06 | Last modified: | 2023-11-01 | Method: | ELECTRON MICROSCOPY (2.87 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8EV6
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with amikacin, mRNA, and A-, P-, and E-site tRNAs | Descriptor: | (2S)-N-[(1R,2S,3S,4R,5S)-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-5-azanyl-2-[(2S,3R,4S,5S ,6R)-4-azanyl-6-(hydroxymethyl)-3,5-bis(oxidanyl)oxan-2-yl]oxy-3-oxidanyl-cyclohexyl]-4-azanyl-2-oxidanyl-butanamide, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Seely, S.M, Gagnon, M.G. | Deposit date: | 2022-10-19 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.946 Å) | Cite: | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8EV7
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with kanamycin, mRNA, and A-, P-, and E-site tRNAs | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Seely, S.M, Gagnon, M.G. | Deposit date: | 2022-10-19 | Release date: | 2023-08-09 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.89 Å) | Cite: | Molecular basis of the pleiotropic effects by the antibiotic amikacin on the ribosome. Nat Commun, 14, 2023
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8EUB
| Hypopseudouridylated yeast 80S bound with Taura syndrome virus (TSV) internal ribosome entry site (IRES), eEF2 and GDP, Structure I | Descriptor: | 18S rRNA, 28S rRNA, 40S ribosomal protein S0-A, ... | Authors: | Zhao, Y, Rai, J, Li, H. | Deposit date: | 2022-10-18 | Release date: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.52 Å) | Cite: | Regulation of translation by ribosomal RNA pseudouridylation. Sci Adv, 9, 2023
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8B7Y
| Cryo-EM structure of the E.coli 70S ribosome in complex with the antibiotic Myxovalargin B. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Koller, T.O, Graf, M, Wilson, D.N. | Deposit date: | 2022-10-03 | Release date: | 2023-01-25 | Last modified: | 2023-02-01 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The Myxobacterial Antibiotic Myxovalargin: Biosynthesis, Structural Revision, Total Synthesis, and Molecular Characterization of Ribosomal Inhibition. J.Am.Chem.Soc., 145, 2023
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8EMM
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8EKB
| Crystal structure of the Thermus thermophilus 70S ribosome in complex with mRNA, deacylated P-site tRNAmet, and thermorubin at 2.70A resolution | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Paranjpe, M.N, Polikanov, Y.S. | Deposit date: | 2022-09-20 | Release date: | 2022-12-21 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin. Nucleic Acids Res., 51, 2023
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8EKC
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8EIU
| E. coli 70S ribosome with A-loop mutations U2554C and U2555C | Descriptor: | 16S rRNA, 23S rRNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ... | Authors: | Nissley, A.J, Penev, P.I, Watson, Z.L, Banfield, J.F, Cate, J.H.D. | Deposit date: | 2022-09-15 | Release date: | 2023-02-01 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (2.24 Å) | Cite: | Rare ribosomal RNA sequences from archaea stabilize the bacterial ribosome. Nucleic Acids Res., 51, 2023
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8B2L
| Cryo-EM structure of the plant 80S ribosome | Descriptor: | 18S rRNA, 25S rRNA, 30S ribosomal protein S15, ... | Authors: | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | Deposit date: | 2022-09-14 | Release date: | 2023-08-23 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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8B0X
| Translating 70S ribosome in the unrotated state (P and E, tRNAs) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Fromm, S.A, O'Connor, K.M, Purdy, M, Bhatt, P.R, Loughran, G, Atkins, J.F, Jomaa, A, Mattei, S. | Deposit date: | 2022-09-08 | Release date: | 2022-11-30 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (1.55 Å) | Cite: | The translating bacterial ribosome at 1.55 angstrom resolution generated by cryo-EM imaging services. Nat Commun, 14, 2023
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8AYE
| E. coli 70S ribosome bound to thermorubin and fMet-tRNA | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Sanyal, S, Parajuli, N.P, Emmerich, A.G. | Deposit date: | 2022-09-02 | Release date: | 2023-03-01 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (1.96 Å) | Cite: | Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria. Nat Commun, 14, 2023
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8AUV
| Cryo-EM structure of the plant 40S subunit | Descriptor: | 18S rRNA, MAGNESIUM ION, POTASSIUM ION, ... | Authors: | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | Deposit date: | 2022-08-25 | Release date: | 2023-06-07 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.38 Å) | Cite: | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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8AP4
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8AM9
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome | Descriptor: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | Authors: | Koller, T.O, Morici, M, Wilson, D.N. | Deposit date: | 2022-08-03 | Release date: | 2023-03-08 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
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8AKN
| Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the terminating ribosome | Descriptor: | 16S ribosomal RNA, 2-acetamido-2-deoxy-alpha-D-galactopyranose, 23S ribosomal RNA, ... | Authors: | Koller, T.O, Morici, M, Wilson, D.N. | Deposit date: | 2022-07-30 | Release date: | 2023-03-08 | Last modified: | 2023-09-06 | Method: | ELECTRON MICROSCOPY (2.3 Å) | Cite: | Structural basis for translation inhibition by the glycosylated drosocin peptide. Nat.Chem.Biol., 19, 2023
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8A98
| CRYO-EM STRUCTURE OF LEISHMANIA MAJOR 80S RIBOSOME : snoRNA MUTANT | Descriptor: | 40S ribosomal protein S12, 40S ribosomal protein S14, 40S ribosomal protein S19-like protein, ... | Authors: | Rajan, K.S, Yonath, A, Bashan, A. | Deposit date: | 2022-06-28 | Release date: | 2023-10-11 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (2.46 Å) | Cite: | Structural and mechanistic insights into the function of Leishmania ribosome lacking a single pseudouridine modification. Cell Rep, 43, 2024
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7Y7E
| Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.41 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7G
| Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.34 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7D
| Structure of the Bacterial Ribosome with human tRNA Asp(Q34) and mRNA(GAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.58 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7H
| Structure of the Bacterial Ribosome with human tRNA Tyr(GalQ34) and mRNA(UAC) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7C
| Structure of the Bacterial Ribosome with human tRNA Asp(G34) and mRNA(GAU) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.51 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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7Y7F
| Structure of the Bacterial Ribosome with human tRNA Asp(ManQ34) and mRNA(GAC) | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Ishiguro, K, Yokoyama, T, Shirouzu, M, Suzuki, T. | Deposit date: | 2022-06-22 | Release date: | 2023-10-25 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.43 Å) | Cite: | Glycosylated queuosines in tRNAs optimize translational rate and post-embryonic growth. Cell, 186, 2023
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8A3W
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