8AM9

Cryo-EM structure of the proline-rich antimicrobial peptide drosocin bound to the elongating ribosome

This is a non-PDB format compatible entry.

Summary for 8AM9

• Entry DOI: 10.2210/pdb8am9/pdb
• Related: 8AKN
• EMDB information: 15488 15523
• Related PRD ID: PRD_002425
• Descriptor: 50S ribosomal protein L33, 30S ribosomal protein S5, 30S ribosomal protein S6, fully modified isoform, ... (61 entities in total)
• Functional Keywords: e.coli, 70s, drosocin, dro1, antimicrobial peptide, proline-rich, pramp, initiator trna, elongation, ribosome, leucine trna
• Biological source: Drosophila melanogaster (fruit fly); More
• Total number of polymer chains: 56
• Total formula weight: 2203313.42

Authors

Koller, T.O.,Morici, M.,Wilson, D.N. (deposition date: 2022-08-03, release date: 2023-03-08, Last modification date: 2024-04-24)

• Primary citation: Koller, T.O.,Morici, M.,Berger, M.,Safdari, H.A.,Lele, D.S.,Beckert, B.,Kaur, K.J.,Wilson, D.N.; Structural basis for translation inhibition by the glycosylated drosocin peptide.; Nat.Chem.Biol., 19:1072-1081, 2023; PubMed: 36997646; DOI: 10.1038/s41589-023-01293-7

Experimental method

ELECTRON MICROSCOPY (2.8 Å)