8AYE

E. coli 70S ribosome bound to thermorubin and fMet-tRNA

This is a non-PDB format compatible entry.

Summary for 8AYE

• Entry DOI: 10.2210/pdb8aye/pdb
• EMDB information: 15712
• Descriptor: 50S ribosomal protein L33, 30S ribosomal protein S4, 30S ribosomal protein S5, ... (58 entities in total)
• Functional Keywords: antibiotic, initiator trna, complex, macromolecule, ribosome
• Biological source: Escherichia coli; More
• Total number of polymer chains: 55
• Total formula weight: 2175376.72

Authors

Sanyal, S.,Parajuli, N.P.,Emmerich, A.G. (deposition date: 2022-09-02, release date: 2023-03-01, Last modification date: 2024-04-24)

• Primary citation: Parajuli, N.P.,Emmerich, A.,Mandava, C.S.,Pavlov, M.Y.,Sanyal, S.; Antibiotic thermorubin tethers ribosomal subunits and impedes A-site interactions to perturb protein synthesis in bacteria.; Nat Commun, 14:918-918, 2023; PubMed: 36806263; DOI: 10.1038/s41467-023-36528-7

Experimental method

ELECTRON MICROSCOPY (1.96 Å)