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1TQL
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BU of 1tql by Molmil
POLIOVIRUS POLYMERASE G1A MUTANT
Descriptor: ACETIC ACID, RNA-directed RNA polymerase
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2004-06-17
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase
Embo J., 23, 2004
1RA6
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BU of 1ra6 by Molmil
Poliovirus Polymerase Full Length Apo Structure
Descriptor: ACETIC ACID, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RDR
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BU of 1rdr by Molmil
POLIOVIRUS 3D POLYMERASE
Descriptor: CALCIUM ION, POLIOVIRUS 3D POLYMERASE
Authors:Hansen, J, Long, A, Schultz, S.
Deposit date:1998-04-28
Release date:1998-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the RNA-dependent RNA polymerase of poliovirus.
Structure, 5, 1997
1VBD
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BU of 1vbd by Molmil
POLIOVIRUS (TYPE 1, MAHONEY STRAIN) COMPLEXED WITH R78206
Descriptor: (METHYLPYRIDAZINE PIPERIDINE PROPYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Grant, R.A, Hiremath, C.N, Filman, D.J, Syed, R, Andries, K, Hogle, J.M.
Deposit date:1996-01-02
Release date:1996-07-11
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structures of poliovirus complexes with anti-viral drugs: implications for viral stability and drug design.
Curr.Biol., 4, 1994
1PO2
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BU of 1po2 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1NG7
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BU of 1ng7 by Molmil
The Solution Structure of the Soluble Domain of Poliovirus 3A Protein
Descriptor: Genome polyprotein [Core protein P3A]
Authors:Strauss, D.M, Glustrom, L.W, Wuttke, D.S.
Deposit date:2002-12-16
Release date:2003-07-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Towards an understanding of the poliovirus replication complex: the solution structure of the soluble domain of the poliovirus 3A protein.
J.Mol.Biol., 330, 2003
1POV
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BU of 1pov by Molmil
ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION
Descriptor: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE
Authors:Basavappa, R, Filman, D.J, Hogle, J.M.
Deposit date:1995-08-10
Release date:1995-12-07
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.
Protein Sci., 3, 1994
1AL2
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BU of 1al2 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT V1160I
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-06-09
Release date:1997-11-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR6
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BU of 1ar6 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1NN8
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BU of 1nn8 by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus
Descriptor: MYRISTIC ACID, coat protein VP1, coat protein VP2, ...
Authors:He, Y, Mueller, S, Chipman, P.R, Bator, C.M, Peng, X, Bowman, V.D, Mukhopadhyay, S, Wimmer, E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2003-01-13
Release date:2004-01-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Complexes of poliovirus serotypes with their common cellular receptor, CD155
J.Virol., 77, 2003
1DGI
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BU of 1dgi by Molmil
Cryo-EM structure of human poliovirus(serotype 1)complexed with three domain CD155
Descriptor: POLIOVIRUS RECEPTOR, VP1, VP2, ...
Authors:He, Y, Bowman, V.D, Mueller, S, Bator, C.M, Bella, J, Peng, X, Baker, T.S, Wimmer, E, Kuhn, R.J, Rossmann, M.G.
Deposit date:1999-11-24
Release date:2000-01-24
Last modified:2024-02-07
Method:ELECTRON MICROSCOPY (22 Å)
Cite:Interaction of the poliovirus receptor with poliovirus.
Proc.Natl.Acad.Sci.USA, 97, 2000
1AR8
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BU of 1ar8 by Molmil
P1/MAHONEY POLIOVIRUS, MUTANT P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1ASJ
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BU of 1asj by Molmil
P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1PO1
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BU of 1po1 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1RA7
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BU of 1ra7 by Molmil
Poliovirus Polymerase with GTP
Descriptor: ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RAJ
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BU of 1raj by Molmil
Poliovirus Polymerase with a 68 residue N-terminal truncation
Descriptor: Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1AR9
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BU of 1ar9 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR7
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BU of 1ar7 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT P1095S + H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
6XBU
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BU of 6xbu by Molmil
polymerase domain of polymerase-theta
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(P*GP*TP*CP*AP*TP*TP*G)-3'), DNA polymerase theta, ...
Authors:Chen, X, Pomerantz, R, Zhao, J.
Deposit date:2020-06-07
Release date:2021-06-09
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.29 Å)
Cite:Pol theta reverse transcribes RNA and promotes RNA-templated DNA repair.
Sci Adv, 7, 2021
4X0P
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BU of 4x0p by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddATP opposite a tetrahydrofuran AP site analog
Descriptor: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA (5'-D(*CP*GP*TP*TP*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2014-11-21
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.911 Å)
Cite:Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
4X0Q
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BU of 4x0q by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddGTP opposite dCMP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*TP*CP*AP*TP*TP*G)-3'), ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2014-11-22
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
3JW6
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BU of 3jw6 by Molmil
Crystal structure of AcMNPV baculovirus polyhedra
Descriptor: 1,2-ETHANEDIOL, Polyhedrin
Authors:Coulibaly, F, Chiu, E, Metcalf, P.
Deposit date:2009-09-17
Release date:2009-12-08
Last modified:2018-07-25
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:The atomic structure of baculovirus polyhedra reveals the independent emergence of infectious crystals in DNA and RNA viruses
Proc.Natl.Acad.Sci.USA, 106, 2009
7ZUS
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BU of 7zus by Molmil
Crystal structure of ternary complex of Pol theta polymerase domain
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*(DDG))-3'), DNA (5'-D(P*TP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*C)-3'), ...
Authors:Krajewski, W.W, Turnbull, A.P, Willis, S, Charles, M, Stockley, M, Heald, R.A.
Deposit date:2022-05-13
Release date:2022-10-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
J.Med.Chem., 65, 2022
7ZX1
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BU of 7zx1 by Molmil
Crystal structure of Pol theta polymerase domain in complex with compound 22
Descriptor: (2~{S},3~{R})-1-[3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]-~{N}-methyl-~{N}-(3-methylphenyl)-3-oxidanyl-pyrrolidine-2-carboxamide, 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*(DDG))-3'), ...
Authors:Krajewski, W.W, Turnbull, A.P, Willis, S, Charles, M, Stockley, M, Heald, R.A.
Deposit date:2022-05-19
Release date:2022-10-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.829 Å)
Cite:Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
J.Med.Chem., 65, 2022
7ZX0
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BU of 7zx0 by Molmil
Crystal structure of Pol theta polymerase domain in complex with compound 5
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, 2-[5-bromanyl-3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl]oxy-~{N}-ethyl-~{N}-(3-methylphenyl)ethanamide, DNA (5'-D(*GP*CP*GP*GP*CP*TP*GP*TP*CP*AP*TP*TP*(DDG))-3'), ...
Authors:Krajewski, W.W, Turnbull, A.P, Willis, S, Charles, M, Stockley, M, Heald, R.A.
Deposit date:2022-05-19
Release date:2022-10-12
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2.99 Å)
Cite:Discovery, Characterization, and Structure-Based Optimization of Small-Molecule In Vitro and In Vivo Probes for Human DNA Polymerase Theta.
J.Med.Chem., 65, 2022

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