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1XYR
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Poliovirus 135S cell entry intermediate
Descriptor: Genome polyprotein, Coat protein VP1, Coat protein VP2, ...
Authors:Bubeck, D, Filman, D.J, Cheng, N, Steven, A.C, Hogle, J.M, Belnap, D.M.
Deposit date:2004-11-10
Release date:2005-08-02
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11 Å)
Cite:The structure of the poliovirus 135S cell entry intermediate at 10-angstrom resolution reveals the location of an externalized polypeptide that binds to membranes.
J.Virol., 79, 2005
1L1N
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BU of 1l1n by Molmil
POLIOVIRUS 3C PROTEINASE
Descriptor: Genome polyprotein: Picornain 3C
Authors:Mosimann, S.C, Chernaia, M.M, Sia, S, Plotch, S, James, M.N.G.
Deposit date:2002-02-19
Release date:2002-04-10
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Refined X-ray crystallographic structure of the poliovirus 3C gene product.
J.Mol.Biol., 273, 1997
1NG7
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BU of 1ng7 by Molmil
The Solution Structure of the Soluble Domain of Poliovirus 3A Protein
Descriptor: Genome polyprotein [Core protein P3A]
Authors:Strauss, D.M, Glustrom, L.W, Wuttke, D.S.
Deposit date:2002-12-16
Release date:2003-07-15
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Towards an understanding of the poliovirus replication complex: the solution structure of the soluble domain of the poliovirus 3A protein.
J.Mol.Biol., 330, 2003
2PLV
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BU of 2plv by Molmil
STRUCTURAL FACTORS THAT CONTROL CONFORMATIONAL TRANSITIONS AND SEROTYPE SPECIFICITY IN TYPE 3 POLIOVIRUS
Descriptor: HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP1), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP2), HUMAN POLIOVIRUS TYPE 1 (SUBUNIT VP3), ...
Authors:Filman, D.J, Hogle, J.M.
Deposit date:1989-10-17
Release date:1989-10-17
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.88 Å)
Cite:Structural factors that control conformational transitions and serotype specificity in type 3 poliovirus
EMBO J., 8, 1989
1NN8
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BU of 1nn8 by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus
Descriptor: MYRISTIC ACID, coat protein VP1, coat protein VP2, ...
Authors:He, Y, Mueller, S, Chipman, P.R, Bator, C.M, Peng, X, Bowman, V.D, Mukhopadhyay, S, Wimmer, E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2003-01-13
Release date:2004-01-27
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (15 Å)
Cite:Complexes of poliovirus serotypes with their common cellular receptor, CD155
J.Virol., 77, 2003
1PO1
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POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R80633, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE BUTYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1RA7
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Poliovirus Polymerase with GTP
Descriptor: ACETIC ACID, GUANOSINE-5'-TRIPHOSPHATE, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RAJ
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BU of 1raj by Molmil
Poliovirus Polymerase with a 68 residue N-terminal truncation
Descriptor: Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RA6
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BU of 1ra6 by Molmil
Poliovirus Polymerase Full Length Apo Structure
Descriptor: ACETIC ACID, Genome polyprotein
Authors:Thompson, A.A, Peersen, O.B.
Deposit date:2003-10-31
Release date:2004-08-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
1RDR
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BU of 1rdr by Molmil
POLIOVIRUS 3D POLYMERASE
Descriptor: CALCIUM ION, POLIOVIRUS 3D POLYMERASE
Authors:Hansen, J, Long, A, Schultz, S.
Deposit date:1998-04-28
Release date:1998-09-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the RNA-dependent RNA polymerase of poliovirus.
Structure, 5, 1997
1POV
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BU of 1pov by Molmil
ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION
Descriptor: MYRISTIC ACID, POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), SPHINGOSINE
Authors:Basavappa, R, Filman, D.J, Hogle, J.M.
Deposit date:1995-08-10
Release date:1995-12-07
Last modified:2023-04-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.
Protein Sci., 3, 1994
1PO2
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BU of 1po2 by Molmil
POLIOVIRUS (TYPE 1, MAHONEY) IN COMPLEX WITH R77975, AN INHIBITOR OF VIRAL REPLICATION
Descriptor: (METHYLPYRIDAZINE PIPERIDINE ETHYLOXYPHENYL)ETHYLACETATE, MYRISTIC ACID, POLIOVIRUS TYPE 1 MAHONEY
Authors:Hiremath, C.N, Filman, D.J, Grant, R.A, Hogle, J.M.
Deposit date:1997-01-08
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Acta Crystallogr.,Sect.D, 53, 1997
1AL2
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BU of 1al2 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT V1160I
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-06-09
Release date:1997-11-19
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR7
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BU of 1ar7 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT P1095S + H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR8
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BU of 1ar8 by Molmil
P1/MAHONEY POLIOVIRUS, MUTANT P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1ASJ
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BU of 1asj by Molmil
P1/MAHONEY POLIOVIRUS, AT CRYOGENIC TEMPERATURE
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR6
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BU of 1ar6 by Molmil
P1/MAHONEY POLIOVIRUS, DOUBLE MUTANT V1160I +P1095S
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
1AR9
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BU of 1ar9 by Molmil
P1/MAHONEY POLIOVIRUS, SINGLE SITE MUTANT H2142Y
Descriptor: MYRISTIC ACID, P1/MAHONEY POLIOVIRUS, SPHINGOSINE
Authors:Wien, M.W, Curry, S, Filman, D.J, Hogle, J.M.
Deposit date:1997-08-11
Release date:1997-12-03
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural studies of poliovirus mutants that overcome receptor defects.
Nat.Struct.Biol., 4, 1997
9BH8
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BU of 9bh8 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology searching conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH6
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BU of 9bh6 by Molmil
Human DNA polymerase theta helicase domain tetramer in the apo form
Descriptor: DNA polymerase theta
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
4X0P
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BU of 4x0p by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddATP opposite a tetrahydrofuran AP site analog
Descriptor: 2',3'-dideoxyadenosine triphosphate, CALCIUM ION, DNA (5'-D(*CP*GP*TP*TP*GP*AP*AP*TP*GP*AP*CP*AP*GP*CP*CP*GP*CP*G)-3'), ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2014-11-21
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.911 Å)
Cite:Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
4X0Q
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BU of 4x0q by Molmil
Ternary complex of human DNA polymerase theta C-terminal domain binding ddGTP opposite dCMP
Descriptor: 2'-3'-DIDEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*GP*TP*CP*CP*AP*AP*TP*GP*AP*CP*AP*G)-3'), DNA (5'-D(P*CP*TP*GP*TP*CP*AP*TP*TP*G)-3'), ...
Authors:Zahn, K.E, Doublie, S.
Deposit date:2014-11-22
Release date:2015-03-18
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.9 Å)
Cite:Human DNA polymerase theta grasps the primer terminus to mediate DNA repair.
Nat.Struct.Mol.Biol., 22, 2015
9BH7
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BU of 9bh7 by Molmil
Human DNA polymerase theta helicase domain dimer in the apo form
Descriptor: DNA polymerase theta
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BHA
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BU of 9bha by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology annealed conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published
9BH9
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BU of 9bh9 by Molmil
Human DNA polymerase theta helicase domain dimer bound to DNA in the microhomology aligning conformation
Descriptor: DNA polymerase theta, Stem-loop DNA with microhomology in the 3' overhang
Authors:Zerio, C.J, Lander, G.C.
Deposit date:2024-04-19
Release date:2024-05-01
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Human polymerase theta helicase positions DNA microhomologies for double-strand break repair
To Be Published

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