1POV

ROLE AND MECHANISM OF THE MATURATION CLEAVAGE OF VP0 IN POLIOVIRUS ASSEMBLY: STRUCTURE OF THE EMPTY CAPSID ASSEMBLY INTERMEDIATE AT 2.9 ANGSTROMS RESOLUTION

Summary for 1POV

• Entry DOI: 10.2210/pdb1pov/pdb
• Descriptor: POLIOVIRUS NATIVE EMPTY CAPSID (TYPE 1), MYRISTIC ACID, SPHINGOSINE, ... (6 entities in total)
• Functional Keywords: picornavirus, icosahedral virus, virus
• Biological source: Human poliovirus 1; More
• Cellular location: Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 2C: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3A: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential). Protein 3B: Virion (Potential). Picornain 3C: Host cytoplasm (Potential). RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side (Potential): P03300 P03300 P03300
• Total number of polymer chains: 3
• Total formula weight: 98014.72

Authors

Basavappa, R.,Filman, D.J.,Hogle, J.M. (deposition date: 1995-08-10, release date: 1995-12-07, Last modification date: 2023-04-19)

• Primary citation: Basavappa, R.,Syed, R.,Flore, O.,Icenogle, J.P.,Filman, D.J.,Hogle, J.M.; Role and mechanism of the maturation cleavage of VP0 in poliovirus assembly: structure of the empty capsid assembly intermediate at 2.9 A resolution.; Protein Sci., 3:1651-1669, 1994; PubMed: 7849583

Experimental method

X-RAY DIFFRACTION (2.8 Å)