7DCP
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![BU of 7dcp by Molmil](/molmil-images/mine/7dcp) | cryo-EM structure of the DEAH-box helicase Prp2 and coactivator Spp2 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PRP2 isoform 1, ... | Authors: | Bai, R, Wan, R, Yan, C, Jia, Q, Zhang, P, Lei, J, Shi, Y. | Deposit date: | 2020-10-26 | Release date: | 2021-01-06 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2. Science, 371, 2021
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7AJU
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![BU of 7aju by Molmil](/molmil-images/mine/7aju) | Cryo-EM structure of the 90S-exosome super-complex (state Post-A1-exosome) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2020-09-29 | Release date: | 2020-12-30 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
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7AJT
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![BU of 7ajt by Molmil](/molmil-images/mine/7ajt) | Cryo-EM structure of the 90S-exosome super-complex (state Pre-A1-exosome) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Flemming, D, Venuta, G.L, Berninghausen, O, Beckmann, R, Hurt, E. | Deposit date: | 2020-09-29 | Release date: | 2020-12-30 | Last modified: | 2021-02-03 | Method: | ELECTRON MICROSCOPY (4.6 Å) | Cite: | Structure of the Maturing 90S Pre-ribosome in Association with the RNA Exosome. Mol.Cell, 81, 2021
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7ABG
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![BU of 7abg by Molmil](/molmil-images/mine/7abg) | Human pre-Bact-1 spliceosome | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Cell division cycle 5-like protein, ... | Authors: | Townsend, C, Kastner, B, Leelaram, M.N, Bertram, K, Stark, H, Luehrmann, R. | Deposit date: | 2020-09-07 | Release date: | 2020-12-23 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (7.8 Å) | Cite: | Mechanism of protein-guided folding of the active site U2/U6 RNA during spliceosome activation. Science, 370, 2020
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7AUD
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![BU of 7aud by Molmil](/molmil-images/mine/7aud) | |
7AUC
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![BU of 7auc by Molmil](/molmil-images/mine/7auc) | |
7APK
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![BU of 7apk by Molmil](/molmil-images/mine/7apk) | Structure of the human THO - UAP56 complex | Descriptor: | Spliceosome RNA helicase DDX39B, THO complex subunit 1, THO complex subunit 2, ... | Authors: | Hohmann, U, Puehringer, T, Plaschka, C. | Deposit date: | 2020-10-17 | Release date: | 2020-12-16 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of the human core transcription-export complex reveals a hub for multivalent interactions. Elife, 9, 2020
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7JL3
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![BU of 7jl3 by Molmil](/molmil-images/mine/7jl3) | Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... | Authors: | Kato, K, Ahmad, S, Hur, S. | Deposit date: | 2020-07-29 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.2 Å) | Cite: | Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
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7JL1
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![BU of 7jl1 by Molmil](/molmil-images/mine/7jl1) | Cryo-EM structure of RIG-I:dsRNA in complex with RIPLET PrySpry domain (monomer) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... | Authors: | Kato, K, Ahmad, S, Hur, S. | Deposit date: | 2020-07-29 | Release date: | 2020-12-09 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases. Mol.Cell, 81, 2021
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7AQO
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![BU of 7aqo by Molmil](/molmil-images/mine/7aqo) | yeast THO-Sub2 complex dimer | Descriptor: | BJ4_G0025130.mRNA.1.CDS.1, EM14S01-3B_G0007820.mRNA.1.CDS.1, TEX1 isoform 1, ... | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | Deposit date: | 2020-10-22 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
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7AOI
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![BU of 7aoi by Molmil](/molmil-images/mine/7aoi) | Trypanosoma brucei mitochondrial ribosome large subunit assembly intermediate | Descriptor: | 50S ribosomal protein L13, 50S ribosomal protein L14, 50S ribosomal protein L17, ... | Authors: | Tobiasson, V, Gahura, O, Aibara, S, Baradaran, R, Zikova, A, Amunts, A. | Deposit date: | 2020-10-14 | Release date: | 2020-12-02 | Last modified: | 2021-03-24 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Interconnected assembly factors regulate the biogenesis of mitoribosomal large subunit. Embo J., 40, 2021
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7APX
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![BU of 7apx by Molmil](/molmil-images/mine/7apx) | yeast THO-Sub2 complex | Descriptor: | ATP-dependent RNA helicase SUB2, Protein TEX1, THO complex subunit 2,Tho2, ... | Authors: | Schuller, S.K, Schuller, J.M, Prabu, R.J, Baumgartner, M, Bonneau, F, basquin, J, Conti, E. | Deposit date: | 2020-10-20 | Release date: | 2020-12-02 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural insights into the nucleic acid remodeling mechanisms of the yeast THO-Sub2 complex. Elife, 9, 2020
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6ZNS
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![BU of 6zns by Molmil](/molmil-images/mine/6zns) | Crystal Structure of DUF1998 helicase MrfA | Descriptor: | Uncharacterized ATP-dependent helicase YprA, ZINC ION | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | Deposit date: | 2020-07-06 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.32 Å) | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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6ZNP
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![BU of 6znp by Molmil](/molmil-images/mine/6znp) | Crystal Structure of DUF1998 helicase MrfA bound to DNA | Descriptor: | CITRIC ACID, Uncharacterized ATP-dependent helicase YprA, ZINC ION, ... | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | Deposit date: | 2020-07-06 | Release date: | 2020-11-25 | Last modified: | 2021-01-20 | Method: | X-RAY DIFFRACTION (3.16 Å) | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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6ZNQ
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![BU of 6znq by Molmil](/molmil-images/mine/6znq) | Crystal Structure of DUF1998 helicase MrfA bound to DNA and AMPPNP | Descriptor: | CITRIC ACID, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Uncharacterized ATP-dependent helicase YprA, ... | Authors: | Roske, J.J, Liu, S, Loll, B, Neu, U, Wahl, M.C. | Deposit date: | 2020-07-06 | Release date: | 2020-11-25 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | A skipping rope translocation mechanism in a widespread family of DNA repair helicases. Nucleic Acids Res., 49, 2021
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6UP3
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![BU of 6up3 by Molmil](/molmil-images/mine/6up3) | |
6UP2
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![BU of 6up2 by Molmil](/molmil-images/mine/6up2) | |
6M6B
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![BU of 6m6b by Molmil](/molmil-images/mine/6m6b) | Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase and ATP-gamma-S | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Shi, J, Wen, A, Feng, Y. | Deposit date: | 2020-03-14 | Release date: | 2020-10-14 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Structural basis of Mfd-dependent transcription termination. Nucleic Acids Res., 48, 2020
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6YXX
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![BU of 6yxx by Molmil](/molmil-images/mine/6yxx) | State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate | Descriptor: | 12S ribosomal RNA, 50S ribosomal protein L13, putative, ... | Authors: | Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2020-05-04 | Release date: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
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6YXY
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![BU of 6yxy by Molmil](/molmil-images/mine/6yxy) | State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate | Descriptor: | 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ... | Authors: | Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N. | Deposit date: | 2020-05-04 | Release date: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis. Mol.Cell, 79, 2020
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7A5P
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![BU of 7a5p by Molmil](/molmil-images/mine/7a5p) | Human C Complex Spliceosome - Medium-resolution PERIPHERY | Descriptor: | Cell division cycle 5-like protein, Crooked neck-like protein 1, Eukaryotic initiation factor 4A-III, ... | Authors: | Bertram, K, Kastner, B. | Deposit date: | 2020-08-21 | Release date: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome. Mol.Cell, 80, 2020
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6ZYM
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![BU of 6zym by Molmil](/molmil-images/mine/6zym) | Human C Complex Spliceosome - High-resolution CORE | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, Cell division cycle 5-like protein, Corepressor interacting with RBPJ 1, ... | Authors: | Bertram, K, Kastner, B. | Deposit date: | 2020-08-02 | Release date: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural Insights into the Roles of Metazoan-Specific Splicing Factors in the Human Step 1 Spliceosome. Mol.Cell, 80, 2020
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6M6A
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![BU of 6m6a by Molmil](/molmil-images/mine/6m6a) | Cryo-EM structure of Thermus thermophilus Mfd in complex with RNA polymerase | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Shi, J, Wen, A, Feng, Y. | Deposit date: | 2020-03-14 | Release date: | 2020-10-14 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (5 Å) | Cite: | Structural basis of Mfd-dependent transcription termination. Nucleic Acids Res., 48, 2020
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6KYV
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![BU of 6kyv by Molmil](/molmil-images/mine/6kyv) | Crystal Structure of RIG-I and hairpin RNA with G-U wobble base pairs | Descriptor: | Probable ATP-dependent RNA helicase DDX58, RNA (5'-R(*GP*GP*UP*AP*GP*AP*CP*GP*CP*UP*UP*CP*GP*GP*CP*GP*UP*UP*UP*GP*CP*C)-3'), ZINC ION | Authors: | Kim, K.-H, Hwang, J, Kim, J.H, Son, K.-P, Jang, Y, Kim, M, Kang, S.-J, Lee, J.-O, Choi, B.-S. | Deposit date: | 2019-09-20 | Release date: | 2020-09-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structural and biophysical properties of RIG-I bound to dsRNA with G-U wobble base pairs. Rna Biol., 17, 2020
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6ZQE
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![BU of 6zqe by Molmil](/molmil-images/mine/6zqe) | Cryo-EM structure of the 90S pre-ribosome from Saccharomyces cerevisiae, state Dis-A (Poly-Ala) | Descriptor: | 13 kDa ribonucleoprotein-associated protein, 18S rRNA, 40S ribosomal protein S1-A, ... | Authors: | Cheng, J, Lau, B, Venuta, G.L, Berninghausen, O, Hurt, E, Beckmann, R. | Deposit date: | 2020-07-09 | Release date: | 2020-09-23 | Last modified: | 2024-05-01 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | 90 S pre-ribosome transformation into the primordial 40 S subunit. Science, 369, 2020
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