PDB: 405 resultsInfo pagesStatus searchChemie searchBIRD

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1PVH	Crystal structure of leukemia inhibitory factor in complex with gp130 Descriptor: IODIDE ION, Interleukin-6 receptor beta chain, Leukemia inhibitory factor Authors: Boulanger, M.J, Bankovich, A.J, Kortemme, T, Baker, D, Garcia, K.C. Deposit date: 2003-06-27 Release date: 2003-10-14 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Convergent mechanisms for recognition of divergent cytokines by the shared signaling receptor gp130. Mol.Cell, 12, 2003
3FL7	Crystal structure of the human ephrin A2 ectodomain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, Ephrin receptor, ... Authors: Walker, J.R, Yermekbayeva, L, Seitova, A, Butler-Cole, C, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) Deposit date: 2008-12-18 Release date: 2009-01-27 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Architecture of Eph receptor clusters. Proc.Natl.Acad.Sci.USA, 107, 2010
1P9M	Crystal structure of the hexameric human IL-6/IL-6 alpha receptor/gp130 complex Descriptor: Interleukin-6, Interleukin-6 receptor alpha chain, Interleukin-6 receptor beta chain Authors: Boulanger, M.J, Chow, D.C, Brevnova, E.E, Garcia, K.C. Deposit date: 2003-05-12 Release date: 2003-07-01 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (3.65 Å) Cite: Hexameric Structure and Assembly of the Interleukin-6/IL-6 alpha-Receptor/gp130 Complex Science, 300, 2003
2Q7N	Crystal structure of Leukemia inhibitory factor in complex with LIF receptor (domains 1-5) Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Huyton, T, Zhang, J.G, Nicola, N.A, Garrett, T.P.J. Deposit date: 2007-06-07 Release date: 2007-07-31 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (4 Å) Cite: An unusual cytokine:Ig-domain interaction revealed in the crystal structure of leukemia inhibitory factor (LIF) in complex with the LIF receptor. Proc.Natl.Acad.Sci.USA, 104, 2007
8Q6T	Helical reconstruction of the relaxed thick filament from FIB milled left ventricular mouse myofibrils Descriptor: Myosin binding protein C, cardiac, Myosin light chain 3, ... Authors: Tamborrini, D, Raunser, S. Deposit date: 2023-08-14 Release date: 2023-11-01 Last modified: 2023-12-06 Method: ELECTRON MICROSCOPY (18 Å) Cite: Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature, 623, 2023
8PMU	Crystal structure of the HC7 apo form Descriptor: DUF3472 domain-containing protein, GLYCEROL Authors: Taleb, V, Hurtado-Guerrero, R. Deposit date: 2023-06-29 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases Nat Catal, 2024
5FMV	Crystal structure of human CD45 extracellular region, domains d1-d4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, SULFATE ION Authors: Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. Deposit date: 2015-11-09 Release date: 2016-03-23 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016
5FM5	Crystal structure of the myomesin:obscurin-like-1 complex Descriptor: MYOMESIN-1, OBSCURIN-LIKE-1 Authors: Pernigo, S, Steiner, R.A. Deposit date: 2015-11-01 Release date: 2016-11-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection. Structure, 25, 2017
6IAA	hRobo2 ectodomain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Barak, R, Isupov, N.M, Opatowsky, Y. Deposit date: 2018-11-26 Release date: 2019-03-13 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural Principles in Robo Activation and Auto-inhibition. Cell, 177, 2019
8QY4	Structure of interleukin 11 (gp130 P496L mutant). Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... Authors: Gardner, S, Bubeck, D, Jin, Y. Deposit date: 2023-10-25 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structure of interleukin 11 (gp130 P496L mutant). To Be Published
8QY6	Structure of interleukin 6 (gp130 P496L mutant). Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... Authors: Gardner, S, Bubeck, D, Jin, Y. Deposit date: 2023-10-25 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structure of interleukin 6 (gp130 P496L mutant). To Be Published
8QY5	Structure of interleukin 6. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... Authors: Gardner, S, Bubeck, D, Jin, Y. Deposit date: 2023-10-25 Release date: 2024-02-21 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structure of interleukin 6. To Be Published
8PN5	Crystal structure of the HC7-Glu200Ala mutant complexed to a triglycopeptide Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-acetamido-2-deoxy-alpha-D-galactopyranose, DUF3472 domain-containing protein, ... Authors: Taleb, V, Hurtado-Guerrero, R. Deposit date: 2023-06-29 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.72 Å) Cite: A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases Nat Catal, 2024
8PN3	Crystal structure of the HC7-Glu200Ala mutant complexed to a tetraglycopeptide. Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, DUF3472 domain-containing protein, GLYCEROL, ... Authors: Taleb, V, Hurtado-Guerrero, R. Deposit date: 2023-06-29 Release date: 2024-03-06 Method: X-RAY DIFFRACTION (1.44 Å) Cite: A family of di-glutamate mucin-degrading enzymes that bridges glycan hydrolases and peptidases Nat Catal, 2024
6M76	GH31 alpha-N-acetylgalactosaminidase from Enterococcus faecalis Descriptor: 1,2-ETHANEDIOL, LPXTG-motif cell wall anchor domain protein Authors: Miyazaki, T. Deposit date: 2020-03-17 Release date: 2020-05-20 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.4 Å) Cite: Crystal structure of the Enterococcus faecalis alpha-N-acetylgalactosaminidase, a member of the glycoside hydrolase family 31. Febs Lett., 594, 2020
6M77	GH31 alpha-N-acetylgalactosaminidase from Enterococcus faecalis in complex with N-acetylgalactosamine Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, ... Authors: Miyazaki, T. Deposit date: 2020-03-17 Release date: 2020-05-20 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal structure of the Enterococcus faecalis alpha-N-acetylgalactosaminidase, a member of the glycoside hydrolase family 31. Febs Lett., 594, 2020
5I99	Crystal structure of mouse CNTN3 Ig5-Fn2 domains Descriptor: Contactin-3, GLYCEROL Authors: Nikolaienko, R.M, Bouyain, S. Deposit date: 2016-02-19 Release date: 2016-08-31 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural Basis for Interactions Between Contactin Family Members and Protein-tyrosine Phosphatase Receptor Type G in Neural Tissues. J.Biol.Chem., 291, 2016
5J7C	A picomolar affinity FN3 domain in complex with hen egg-white lysozyme Descriptor: FNfn10-anti-lysozyme (DE0.4.1), Lysozyme C Authors: Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M. Deposit date: 2016-04-06 Release date: 2016-08-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.535 Å) Cite: Circumventing the stability-function trade-off in an engineered FN3 domain. Protein Eng.Des.Sel., 2016
6MOH	Dimeric DARPin C_R3 complex with EpoR Descriptor: Dimeric DARPin E2C (C_R3), Erythropoietin receptor, PHOSPHATE ION, ... Authors: Jude, K.M, Mohan, K, Garcia, K.C. Deposit date: 2018-10-04 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.2 Å) Cite: Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
6MOI	Dimeric DARPin C_angle_R5 complex with EpoR Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Dimeric DARPing CCR5 (C_angle_R5), ... Authors: Jude, K.M, Mohan, K, Garcia, K.C, Guo, Y. Deposit date: 2018-10-04 Release date: 2019-06-05 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.065 Å) Cite: Topological control of cytokine receptor signaling induces differential effects in hematopoiesis. Science, 364, 2019
7SL2	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- asymmetric conformation Descriptor: Insulin A chain, Insulin B chain, Insulin receptor Authors: Bai, X.C, Choi, E. Deposit date: 2021-10-22 Release date: 2022-03-30 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL6	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- symmetric conformation Descriptor: Insulin A chain, Insulin B chain, Insulin receptor Authors: Bai, X.C, Choi, E. Deposit date: 2021-10-22 Release date: 2022-03-30 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.7 Å) Cite: Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL3	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (A-L13R) -- symmetric conformation Descriptor: Insulin A chain, Insulin B chain, Insulin receptor Authors: Bai, X.C, Choi, E. Deposit date: 2021-10-22 Release date: 2022-03-30 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.4 Å) Cite: Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL4	Full-length insulin receptor bound with site 2 binding deficient mutant insulin (B-L17R) -- asymmetric conformation Descriptor: Insulin A chain, Insulin B chain, Insulin receptor Authors: Bai, X.C, Choi, E. Deposit date: 2021-10-22 Release date: 2022-03-30 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (5 Å) Cite: Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022
7SL7	Full-length insulin receptor bound with both site 1 binding deficient mutant insulin (A-V3E) and site 2 binding deficient mutant insulin (A-L13R) Descriptor: Insulin A chain (L13R), Insulin A chain (V3E), Insulin B chain, ... Authors: Bai, X.C, Choi, E. Deposit date: 2021-10-22 Release date: 2022-03-30 Last modified: 2022-04-27 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Synergistic activation of the insulin receptor via two distinct sites. Nat.Struct.Mol.Biol., 29, 2022

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