2LMJ
 
 | | Itk-sh3 | | Descriptor: | Tyrosine-protein kinase ITK/TSK | | Authors: | Kristiansen, P, Bie Andersen, T, Huszenicza, Z, Andreotti, A.H, Spurkland, A. | | Deposit date: | 2011-12-05 | | Release date: | 2012-12-05 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | The SH3 domains of the Tec family kinase Itk and the Src family kinase Lck compete for adjacent sites on T-cell specific adapter protein
To be Published
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3UF4
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4A63
 | | Crystal structure of the p73-ASPP2 complex at 2.6A resolution | | Descriptor: | ACETATE ION, APOPTOSIS STIMULATING OF P53 PROTEIN 2, TUMOUR PROTEIN 73, ... | | Authors: | Canning, P, Sharpe, T, Krojer, T, Savitsky, P, Cooper, C.D.O, Salah, E, Keates, T, Muniz, J, Vollmar, M, von Delft, F, Weigelt, J, Arrowsmith, C, Bountra, C, Edwards, A, Bullock, A.N. | | Deposit date: | 2011-10-31 | | Release date: | 2011-12-21 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (2.27 Å) | | Cite: | Structural Basis for Aspp2 Recognition by the Tumor Suppressor P73.
J.Mol.Biol., 423, 2012
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3UAT
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3UA7
 | | Crystal Structure of the Human Fyn SH3 domain in complex with a peptide from the Hepatitis C virus NS5A-protein | | Descriptor: | CHLORIDE ION, FORMIC ACID, GLYCEROL, ... | | Authors: | Martin-Garcia, J.M, Ruiz-Sanz, J, Luque, I, Camara-Artigas, A. | | Deposit date: | 2011-10-21 | | Release date: | 2012-07-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | The promiscuous binding of the Fyn SH3 domain to a peptide from the NS5A protein.
Acta Crystallogr.,Sect.D, 68, 2012
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3UA6
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3TVT
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2LJ3
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3THK
 | | Structure of SH3 chimera with a type II ligand linked to the chain C-terminal | | Descriptor: | BETA-MERCAPTOETHANOL, Proline-rich peptide, SULFATE ION, ... | | Authors: | Gabdulkhakov, A.G, Gushchina, L.V, Nikulin, A.D, Nikonov, S.V, Filimonov, V.V. | | Deposit date: | 2011-08-19 | | Release date: | 2011-11-23 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | High-Resolution Crystal Structure of Spectrin SH3 Domain Fused with a Proline-Rich Peptide.
J.Biomol.Struct.Dyn., 29, 2011
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2LCS
 | | Yeast Nbp2p SH3 domain in complex with a peptide from Ste20p | | Descriptor: | NAP1-binding protein 2, Serine/threonine-protein kinase STE20 | | Authors: | Gorelik, M, Davidson, A.R. | | Deposit date: | 2011-05-07 | | Release date: | 2012-02-01 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Distinct Peptide Binding Specificities of Src Homology 3 (SH3) Protein Domains Can Be Determined by Modulation of Local Energetics across the Binding Interface.
J.Biol.Chem., 287, 2012
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3REB
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3REA
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3RBB
 | | HIV-1 NEF protein in complex with engineered HCK SH3 domain | | Descriptor: | 1,2-ETHANEDIOL, Protein Nef, Tyrosine-protein kinase HCK | | Authors: | Horenkamp, F.A, Schulte, A, Weyand, M, Geyer, M. | | Deposit date: | 2011-03-29 | | Release date: | 2011-04-27 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.35 Å) | | Cite: | Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly.
Traffic, 12, 2011
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3QWX
 | | CED-2 1-174 | | Descriptor: | Cell death abnormality protein 2, SULFATE ION | | Authors: | Kang, Y, Sun, J, Liu, Y. | | Deposit date: | 2011-02-28 | | Release date: | 2011-06-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.01 Å) | | Cite: | Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans.
Biochem.Biophys.Res.Commun., 410, 2011
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3QWY
 | | CED-2 | | Descriptor: | Cell death abnormality protein 2, GLYCEROL, SULFATE ION | | Authors: | Kang, Y, Sun, J, Liu, Y, Sun, D, Hu, Y, Liu, Y.F. | | Deposit date: | 2011-02-28 | | Release date: | 2011-06-08 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.52 Å) | | Cite: | Crystal structure of the cell corpse engulfment protein CED-2 in Caenorhabditis elegans.
Biochem.Biophys.Res.Commun., 410, 2011
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2L3S
 | | Structure of the autoinhibited Crk | | Descriptor: | Autoinhibited Crk protein | | Authors: | Kalodimos, C.G, Sarkar, P, Saleh, T, Tzeng, S.R, Birge, R. | | Deposit date: | 2010-09-21 | | Release date: | 2010-12-08 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structural basis for regulation of the Crk signaling protein by a proline switch.
Nat.Chem.Biol., 7, 2011
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2L2P
 | | Folding Intermediate of the Fyn SH3 A39V/N53P/V55L from NMR Relaxation Dispersion Experiments | | Descriptor: | Tyrosine-protein kinase Fyn | | Authors: | Neudecker, P, Robustelli, P, Cavalli, A, Vendruscolo, M, Kay, L.E. | | Deposit date: | 2010-08-25 | | Release date: | 2011-09-14 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Structure of an intermediate state in protein folding and aggregation.
Science, 336, 2012
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2XMF
 | | Myosin 1e SH3 | | Descriptor: | MYOSIN 1E SH3, OCTANE 1,8-DIAMINE | | Authors: | Edwards, T, Allsop, G, Peckham, M. | | Deposit date: | 2010-07-27 | | Release date: | 2011-08-10 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Myosin 1E SH3
To be Published
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2XKX
 | | Single particle analysis of PSD-95 in negative stain | | Descriptor: | DISKS LARGE HOMOLOG 4 | | Authors: | Fomina, S, Howard, T.D, Sleator, O.K, Golovanova, M, O'Ryan, L, Leyland, M.L, Grossmann, J.G, Collins, R.F, Prince, S.M. | | Deposit date: | 2010-07-15 | | Release date: | 2011-07-20 | | Last modified: | 2024-05-08 | | Method: | ELECTRON MICROSCOPY (22.9 Å), SOLUTION SCATTERING | | Cite: | Self-Directed Assembly and Clustering of the Cytoplasmic Domains of Inwardly Rectifying Kir2.1 Potassium Channels on Association with Psd-95
Biochim.Biophys.Acta, 1808, 2011
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2L0A
 | | Solution NMR Structure of Signal transducing adapter molecule 1 STAM-1 from Homo sapiens, Northeast Structural Genomics Consortium Target HR4479E | | Descriptor: | Signal transducing adapter molecule 1 | | Authors: | Tang, Y, Janjua, H, Ciccosanti, C, Shastry, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | | Deposit date: | 2010-06-30 | | Release date: | 2010-07-21 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | Northeast Structural Genomics Consortium Target HR4479E
To be Published
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3NMZ
 | | Crystal structure of APC complexed with Asef | | Descriptor: | APC variant protein, Rho guanine nucleotide exchange factor 4 | | Authors: | Zhang, Z, Chen, L, Gao, L, Lin, K, Wu, G. | | Deposit date: | 2010-06-23 | | Release date: | 2011-07-06 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (3.01 Å) | | Cite: | Structural basis for the recognition of Asef by adenomatous polyposis coli.
Cell Res., 22, 2012
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3NHN
 | | Crystal structure of the SRC-family kinase HCK SH3-SH2-linker regulatory region | | Descriptor: | Tyrosine-protein kinase HCK | | Authors: | Alvarado, J.J, Betts, L, Moroco, J.A, Smithgall, T.E, Yeh, J.I. | | Deposit date: | 2010-06-14 | | Release date: | 2010-09-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.61 Å) | | Cite: | Crystal Structure of the Src Family Kinase Hck SH3-SH2 Linker Regulatory Region Supports an SH3-dominant Activation Mechanism.
J.Biol.Chem., 285, 2010
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3NGP
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2KYM
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2KXD
 | | The structure of SH3-F2 | | Descriptor: | 11-mer peptide,Spectrin alpha chain, non-erythrocytic 1,Spectrin alpha chain, non-erythrocytic 1 | | Authors: | Kutyshenko, V.P, Gushchina, L.V, Khristoforov, V.S, Prokhorov, D.A, Timchenko, M.A, Kudrevatykh, I.u.A, Fedyukina, D.V, Filimonov, V.V. | | Deposit date: | 2010-04-30 | | Release date: | 2011-04-20 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | NMR structure and dynamics of the chimeric protein SH3-F2
Mol.Biol.(Engl.Transl.), 44, 2010
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