4W2E
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![BU of 4w2e by Molmil](/molmil-images/mine/4w2e) | Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Lin, J, Steitz, T.A. | Deposit date: | 2014-06-04 | Release date: | 2014-10-01 | Last modified: | 2023-07-26 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome. Science, 345, 2014
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5FDU
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![BU of 5fdu by Molmil](/molmil-images/mine/5fdu) | Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Seefeldt, A.C, Graf, M, Perebaskine, N, Nguyen, F, Arenz, S, Mardirossian, M, Scocchi, M, Wilson, D.N, Innis, C.A. | Deposit date: | 2015-12-16 | Release date: | 2016-01-27 | Last modified: | 2024-04-24 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome. Nucleic Acids Res., 44, 2016
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4Z8C
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![BU of 4z8c by Molmil](/molmil-images/mine/4z8c) | Crystal structure of the Thermus thermophilus 70S ribosome bound to translation inhibitor oncocin | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Roy, R.N, Lomakin, I.B, Gagnon, M.G, Steitz, T.A. | Deposit date: | 2015-04-08 | Release date: | 2015-05-20 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | The mechanism of inhibition of protein synthesis by the proline-rich peptide oncocin. Nat.Struct.Mol.Biol., 22, 2015
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1VY6
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![BU of 1vy6 by Molmil](/molmil-images/mine/1vy6) | Crystal structure of the Thermus thermophilus 70S ribosome in the pre-attack state of peptide bond formation containing short substrate-mimic Cytidine-Puromycin in the A site and acylated tRNA in the P site. | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Polikanov, Y.S, Steitz, T.A, Innis, C.A. | Deposit date: | 2014-05-13 | Release date: | 2014-08-20 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | A proton wire to couple aminoacyl-tRNA accommodation and peptide-bond formation on the ribosome. Nat.Struct.Mol.Biol., 21, 2014
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4LNT
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![BU of 4lnt by Molmil](/molmil-images/mine/4lnt) | Crystal Structure of tRNA Proline (CGG) Bound to Codon CCC-U on the Ribosome | Descriptor: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | Authors: | Maehigashi, T, Dunkle, J.A, Dunham, C.M. | Deposit date: | 2013-07-12 | Release date: | 2014-08-06 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (2.94 Å) | Cite: | Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops. Proc.Natl.Acad.Sci.USA, 111, 2014
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4V90
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![BU of 4v90 by Molmil](/molmil-images/mine/4v90) | Thermus thermophilus Ribosome | Descriptor: | 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Chen, Y, Feng, S, Kumar, V, Ero, R, Gao, Y.G. | Deposit date: | 2014-02-22 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structure of EF-G-ribosome complex in a pretranslocation state. Nat. Struct. Mol. Biol., 20, 2013
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5NDK
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![BU of 5ndk by Molmil](/molmil-images/mine/5ndk) | Crystal structure of aminoglycoside TC007 co-crystallized with 70S ribosome from Thermus thermophilus, three tRNAs and mRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G. | Deposit date: | 2017-03-08 | Release date: | 2017-12-13 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Aminoglycoside interactions and impacts on the eukaryotic ribosome. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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4WSD
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![BU of 4wsd by Molmil](/molmil-images/mine/4wsd) | Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site and with antibiotic paromomycin. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-27 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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5IBB
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![BU of 5ibb by Molmil](/molmil-images/mine/5ibb) | Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and cognate tRNAVal in the A-site | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2016-02-22 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.96 Å) | Cite: | The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
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5IB7
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![BU of 5ib7 by Molmil](/molmil-images/mine/5ib7) | Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet, near-cognate tRNALys with U-G mismatch in the A-site and antibiotic paromomycin | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2016-02-22 | Release date: | 2016-05-25 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The ribosome prohibits the GU wobble geometry at the first position of the codon-anticodon helix. Nucleic Acids Res., 44, 2016
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4V8B
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![BU of 4v8b by Molmil](/molmil-images/mine/4v8b) | Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex). | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2011-12-06 | Release date: | 2014-07-09 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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4V8G
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![BU of 4v8g by Molmil](/molmil-images/mine/4v8g) | Crystal structure of RMF bound to the 70S ribosome. | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Polikanov, Y.S, Blaha, G.M, Steitz, T.A. | Deposit date: | 2011-12-11 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science, 336, 2012
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4V9R
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![BU of 4v9r by Molmil](/molmil-images/mine/4v9r) | Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | Deposit date: | 2013-12-05 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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4V7Y
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![BU of 4v7y by Molmil](/molmil-images/mine/4v7y) | Structure of the Thermus thermophilus 70S ribosome complexed with azithromycin. | Descriptor: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. | Deposit date: | 2010-08-18 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7W
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![BU of 4v7w by Molmil](/molmil-images/mine/4v7w) | Structure of the Thermus thermophilus ribosome complexed with chloramphenicol. | Descriptor: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. | Deposit date: | 2010-08-16 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V7L
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![BU of 4v7l by Molmil](/molmil-images/mine/4v7l) | The structures of viomycin bound to the 70S ribosome. | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Stanley, R.E, Blaha, G. | Deposit date: | 2009-11-12 | Release date: | 2014-07-09 | Last modified: | 2018-07-11 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat.Struct.Mol.Biol., 17, 2010
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4V7X
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![BU of 4v7x by Molmil](/molmil-images/mine/4v7x) | Structure of the Thermus thermophilus ribosome complexed with erythromycin. | Descriptor: | 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. | Deposit date: | 2010-08-17 | Release date: | 2014-07-09 | Last modified: | 2014-12-10 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
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4V8D
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![BU of 4v8d by Molmil](/molmil-images/mine/4v8d) | Structure analysis of ribosomal decoding (cognate tRNA-tyr complex). | Descriptor: | 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | Authors: | Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2011-12-07 | Release date: | 2014-07-09 | Last modified: | 2019-07-03 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
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5HAU
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![BU of 5hau by Molmil](/molmil-images/mine/5hau) | Crystal structure of antimicrobial peptide Bac7(1-19) bound to the Thermus thermophilus 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Gagnon, M.G, Roy, R.N, Lomakin, I.B, Florin, T, Mankin, A.S, Steitz, T.A. | Deposit date: | 2015-12-30 | Release date: | 2016-04-06 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Structures of proline-rich peptides bound to the ribosome reveal a common mechanism of protein synthesis inhibition. Nucleic Acids Res., 44, 2016
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5J3C
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![BU of 5j3c by Molmil](/molmil-images/mine/5j3c) | |
4WT1
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![BU of 4wt1 by Molmil](/molmil-images/mine/4wt1) | Complex of 70S ribosome with tRNA-Phe and mRNA with A-A mismatch in the second position in the A-site | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-29 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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4WRO
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![BU of 4wro by Molmil](/molmil-images/mine/4wro) | Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G. | Deposit date: | 2014-10-24 | Release date: | 2015-06-10 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural insights into the translational infidelity mechanism. Nat Commun, 6, 2015
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5DFE
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![BU of 5dfe by Molmil](/molmil-images/mine/5dfe) | 70S termination complex containing E. coli RF2 | Descriptor: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Hoffer, E.D, Dunham, C.M. | Deposit date: | 2015-08-26 | Release date: | 2016-10-12 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (3.09997559 Å) | Cite: | Uniformity of Peptide Release Is Maintained by Methylation of Release Factors. Cell Rep, 17, 2016
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4V9S
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![BU of 4v9s by Molmil](/molmil-images/mine/4v9s) | Crystal structure of antibiotic GE82832 bound to 70S ribosome | Descriptor: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... | Authors: | Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A. | Deposit date: | 2013-12-05 | Release date: | 2014-07-09 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation. Cell Rep, 6, 2014
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4V5L
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![BU of 4v5l by Molmil](/molmil-images/mine/4v5l) | The structure of EF-Tu and aminoacyl-tRNA bound to the 70S ribosome with a GTP analog | Descriptor: | 16S RRNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... | Authors: | Voorhees, R.M, Schmeing, T.M, Ramakrishnan, V. | Deposit date: | 2010-09-02 | Release date: | 2014-07-09 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The Mechanism for Activation of GTP Hydrolysis on the Ribosome. Science, 330, 2010
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