5FDU

Crystal structure of the Metalnikowin I antimicrobial peptide bound to the Thermus thermophilus 70S ribosome

This is a non-PDB format compatible entry.

Summary for 5FDU

• Entry DOI: 10.2210/pdb5fdu/pdb
• Descriptor: 23S ribosomal RNA, 50S ribosomal protein L14, 50S ribosomal protein L15, ... (59 entities in total)
• Functional Keywords: bacterial ribosome, proline-rich antimicrobial peptide, antibiotics, protein biosynthesis, ribosome
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 108
• Total formula weight: 4368310.47

Authors

Seefeldt, A.C.,Graf, M.,Perebaskine, N.,Nguyen, F.,Arenz, S.,Mardirossian, M.,Scocchi, M.,Wilson, D.N.,Innis, C.A. (deposition date: 2015-12-16, release date: 2016-01-27, Last modification date: 2024-04-24)

• Primary citation: Seefeldt, A.C.,Graf, M.,Perebaskine, N.,Nguyen, F.,Arenz, S.,Mardirossian, M.,Scocchi, M.,Wilson, D.N.,Innis, C.A.; Structure of the mammalian antimicrobial peptide Bac7(1-16) bound within the exit tunnel of a bacterial ribosome.; Nucleic Acids Res., 44:2429-2438, 2016; PubMed: 26792896; DOI: 10.1093/nar/gkv1545

Experimental method

X-RAY DIFFRACTION (2.9 Å)