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PDB: 109 results
2WRY
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BU of 2wry by Molmil
Crystal structure of chicken cytokine interleukin 1 beta
Descriptor: INTERLEUKIN-1BETA
Authors:Lu, W.S, Cheng, C.S, Lyu, P.C, Lee, L.H, Wang, W.C, Yin, H.S.
Deposit date:2009-09-03
Release date:2010-09-29
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.58 Å)
Cite:Structural and Functional Comparison of Cytokine Interleukin-1 Beta from Chicken and Human.
Mol.Immunol., 48, 2011
5HN1
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BU of 5hn1 by Molmil
Crystal structure of Interleukin-37
Descriptor: Interleukin-37, SULFATE ION
Authors:Ellisdon, A.M, Nold-Petry, C.A, Nold, M.F, Whisstock, J.C.
Deposit date:2016-01-17
Release date:2017-02-22
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Homodimerization attenuates the anti-inflammatory activity of interleukin-37.
Sci Immunol, 2, 2017
6HPI
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BU of 6hpi by Molmil
NMR structure of the pro-inflammatory cytokine interleukin-36alpha
Descriptor: Interleukin-36 alpha
Authors:Ohlenschlaeger, O, Imhof, D.
Deposit date:2018-09-21
Release date:2019-10-02
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:(1)H, (13)C, and (15)N resonance assignments for the pro-inflammatory cytokine interleukin-36alpha.
Biomol NMR Assign, 10, 2016
7CHZ
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BU of 7chz by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26A
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26A, light chain of antibody binding fragment of IgG26A
Authors:Lee, C.C, Wang, A.H.J, Kuo, W.C.
Deposit date:2020-07-06
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
7CHY
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BU of 7chy by Molmil
Crystal Structure Of Human Il-1beta In Complex With Antibody Binding Fragment Of IgG26
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of IgG26, light chain of antibody binding fragment of IgG26
Authors:Lee, C.C, Wang, A.H.J, Kuo, W.C.
Deposit date:2020-07-06
Release date:2021-01-13
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure-based Development of Human Interleukin-1 beta-Specific Antibody That Simultaneously Inhibits Binding to Both IL-1RI and IL-1RAcP.
J.Mol.Biol., 433, 2020
5I1B
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BU of 5i1b by Molmil
A COMPARISON OF THE HIGH RESOLUTION STRUCTURES OF HUMAN AND MURINE INTERLEUKIN-1B
Descriptor: INTERLEUKIN-1 BETA
Authors:Ohlendorf, D.H, Salemme, F.R.
Deposit date:1990-09-07
Release date:1992-01-15
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:A Comparison of the High Resolution Structures of Human and Murine Interleukin-1B
To be Published
4EEE
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BU of 4eee by Molmil
Crystal Structure of YLDV 14L IL-18 Binding Protein in Complex with Human IL-18
Descriptor: 14L protein, Interleukin-18
Authors:Krumm, B.E, Xiang, Y, Deng, J.
Deposit date:2012-03-28
Release date:2012-09-26
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:A unique bivalent binding and inhibition mechanism by the yatapoxvirus interleukin 18 binding protein.
Plos Pathog., 8, 2012
3LTQ
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BU of 3ltq by Molmil
Structure of Interleukin 1B solved by SAD using an inserted Lanthanide Binding Tag
Descriptor: ACETATE ION, Interleukin-1 beta, SULFATE ION, ...
Authors:Peisach, E, Allen, K.N.
Deposit date:2010-02-16
Release date:2011-02-16
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Engineering encodable lanthanide-binding tags into loop regions of proteins.
J.Am.Chem.Soc., 133, 2011
3NJ5
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BU of 3nj5 by Molmil
Crystal structure of chicken IL-1 hydrophobic cavity mutant 157
Descriptor: IL-1 beta
Authors:Yin, H.S, Chen, Y.W.
Deposit date:2010-06-17
Release date:2011-06-22
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.67 Å)
Cite:Structural and functional comparison of cytokine interleukin-1 beta from chicken and human
Mol.Immunol., 48, 2011
4P0L
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BU of 4p0l by Molmil
Crystal Structure of Double Loop-Swapped Interleukin-36Ra With Additional Point Mutations
Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2014-02-21
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J Immunol., 193, 2014
4P0K
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BU of 4p0k by Molmil
Crystal Structure of Double Loop-Swapped Interleukin-36Ra
Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2014-02-21
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J Immunol., 193, 2014
4P0J
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BU of 4p0j by Molmil
Crystal Structure of Loop-Swapped Interleukin-36Ra
Descriptor: Interleukin-36 receptor antagonist/Interleukin-36 gamma chimera protein
Authors:Guenther, S, Sundberg, E.J.
Deposit date:2014-02-21
Release date:2014-06-25
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.298 Å)
Cite:Molecular Determinants of Agonist and Antagonist Signaling through the IL-36 Receptor.
J Immunol., 193, 2014
3WO2
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BU of 3wo2 by Molmil
Crystal structure of human interleukin-18
Descriptor: 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-1-PROPANESULFONATE, Interleukin-18, SULFATE ION
Authors:Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H.
Deposit date:2013-12-19
Release date:2014-12-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.33 Å)
Cite:The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
3WO3
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BU of 3wo3 by Molmil
Crystal structure of IL-18 in complex with IL-18 receptor alpha
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Tsutsumi, N, Kimura, T, Arita, K, Ariyoshi, M, Ohnishi, H, Kondo, N, Shirakawa, M, Kato, Z, Tochio, H.
Deposit date:2013-12-19
Release date:2014-12-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The structural basis for receptor recognition of human interleukin-18
Nat Commun, 5, 2014
4R6U
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BU of 4r6u by Molmil
IL-18 receptor complex
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-18, Interleukin-18 receptor 1
Authors:Wei, H, Wang, X.
Deposit date:2014-08-26
Release date:2014-10-15
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the specific recognition of IL-18 by its alpha receptor.
Febs Lett., 588, 2014
41BI
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BU of 41bi by Molmil
INTERLEUKIN-1 BETA (IL-1 BETA) (MUTANT WITH CYS 8 REPLACED BY ALA (C8A)
Descriptor: INTERLEUKIN-1 BETA
Authors:Veerapandian, B, Poulos, T.L, Gilliland, G.L, Masui, Y, Hirai, Y.
Deposit date:1992-02-03
Release date:1992-04-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:

4X3A
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BU of 4x3a by Molmil
gallus interleukin-1 beta mutant - R140A
Descriptor: IL-1 beta
Authors:Yin, H.S, Cheng, W.T.
Deposit date:2014-11-28
Release date:2015-12-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:gallus interleukin-1 beta mutant - R140A
To Be Published
4X37
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BU of 4x37 by Molmil
Gallus interleukin-1 mutant - E118K
Descriptor: IL-1 beta
Authors:Yin, H.S, Cheng, W.T, Cheng, T.
Deposit date:2014-11-28
Release date:2015-12-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.63 Å)
Cite:Gallus interleukin-1 mutant - E118K
To Be Published
4X39
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BU of 4x39 by Molmil
Gallus interleukin-1 beta mutant - T117A
Descriptor: IL-1 beta
Authors:Yin, H.S, Cheng, W.T.
Deposit date:2014-11-28
Release date:2015-12-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Gallus interleukin-1 beta mutant - T117A
To Be Published
4X38
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BU of 4x38 by Molmil
Gallus interleukin-1 beta mutant - E118A
Descriptor: IL-1 beta
Authors:Yin, H.S, Cheng, W.T.
Deposit date:2014-11-28
Release date:2015-12-09
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Gallus interleukin-1 beta mutant - E118A
To Be Published
4XFU
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BU of 4xfu by Molmil
Structure of IL-18 SER Mutant V
Descriptor: Interleukin-18
Authors:Krumm, B.E, Meng, X, Xiang, Y, Deng, J.
Deposit date:2014-12-29
Release date:2015-06-10
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Crystallization of interleukin-18 for structure-based inhibitor design.
Acta Crystallogr.,Sect.F, 71, 2015
4G6J
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BU of 4g6j by Molmil
Crystal structure of human IL-1beta in complex with the therapeutic antibody binding fragment of canakinumab
Descriptor: Interleukin-1 beta, heavy chain of antibody binding fragment of canakinumab, light chain of antibody binding fragment of canakinumab
Authors:Blech, M, Hoerer, S.
Deposit date:2012-07-19
Release date:2012-12-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:One traget-two different binding modes: Structural insights into gevokizumab and canakinumab interactions to interleukin-1beta
J.Mol.Biol., 425, 2013
1TOO
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BU of 1too by Molmil
Interleukin 1B Mutant F146W
Descriptor: Interleukin-1 beta
Authors:Adamek, D.H, Guerrero, L, Caspar, D.L.
Deposit date:2004-06-14
Release date:2004-12-07
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
1TP0
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BU of 1tp0 by Molmil
Triple mutation in interleukin 1 beta cavity:replacement of phenylalanines with tryptophan.
Descriptor: Interleukin-1 beta
Authors:Adamek, D.H, Guerrero, L, Caspar, D.L.
Deposit date:2004-06-15
Release date:2005-02-08
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and energetic consequences of mutations in a solvated hydrophobic cavity.
J.Mol.Biol., 346, 2005
2ILA
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BU of 2ila by Molmil
STRUCTURE OF INTERLEUKIN 1ALPHA AT 2.7-ANGSTROMS RESOLUTION
Descriptor: INTERLEUKIN-1 ALPHA
Authors:Graves, B.J, Hatada, M.H.
Deposit date:1991-05-01
Release date:1992-10-15
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of interleukin 1 alpha at 2.7-A resolution.
Biochemistry, 29, 1990

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