Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 1371 results

4COH
DownloadVisualize
BU of 4coh by Molmil
Crystal structure of Trypanosoma cruzi CYP51 bound to the sulfonamide derivative of the 4-aminopyridyl-based inhibitor
Descriptor: 2-fluoranyl-N-[(2R)-3-(1H-indol-3-yl)-1-oxidanylidene-1-(pyridin-4-ylamino)propan-2-yl]-4-(4-thiophen-2-ylsulfonylpiperazin-1-yl)benzamide, PROTOPORPHYRIN IX CONTAINING FE, STEROL 14-ALPHA DEMETHYLASE
Authors:Vieira, D.F, Choi, J.Y, Roush, W.R, Podust, L.M.
Deposit date:2014-01-28
Release date:2014-04-02
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Expanding the Binding Envelope of Cyp51 Inhibitors Targeting Trypanosoma Cruzi with 4-Aminopyridyl-Based Sulfonamide Derivatives
Chembiochem, 15, 2014
4D78
DownloadVisualize
BU of 4d78 by Molmil
Cytochrome P450 3A4 bound to an inhibitor
Descriptor: CYTOCHROME P450 3A4, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Sevrioukova, I, Poulos, T.
Deposit date:2014-11-21
Release date:2015-09-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure-Based Inhibitor Design for Evaluation of a Cyp3A4 Pharmacophore Model.
J.Med.Chem., 59, 2016
4C28
DownloadVisualize
BU of 4c28 by Molmil
Crystal structure of Trypanosoma cruzi CYP51 bound to the inhibitor (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(4-chlorophenyl)piperazin-1-yl)-2-fluorobenzamide.
Descriptor: (R)-N-(3-(1H-indol-3-yl)-1-oxo-1-(pyridin-4-ylamino)propan-2-yl)-4-(4-(4-chlorophenyl)piperazin-1-yl)-2-fluorobenzamide, 1,2-ETHANEDIOL, CHLORIDE ION, ...
Authors:Vieira, D.F, Calvet, C.M, Choi, J.Y, Cameron, M.D, Gut, J, Kellar, D, Siqueira-Neto, J.L, McKerrow, J.H, Roush, W.R, Podust, L.M.
Deposit date:2013-08-16
Release date:2014-09-03
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Binding Mode and Potency of N-Indolyl-Oxopyridinyl-4-Amino-Propanyl-Based Inhibitors Targeting Trypanosoma Cruzi Cyp51
J.Med.Chem., 57, 2014
4CPP
DownloadVisualize
BU of 4cpp by Molmil
CRYSTAL STRUCTURES OF CYTOCHROME P450-CAM COMPLEXED WITH CAMPHANE, THIOCAMPHOR, AND ADAMANTANE: FACTORS CONTROLLING P450 SUBSTRATE HYDROXYLATION
Descriptor: ADAMANTANE, CYTOCHROME P450-CAM, PROTOPORPHYRIN IX CONTAINING FE
Authors:Raag, R, Poulos, T.L.
Deposit date:1990-05-18
Release date:1991-07-15
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.11 Å)
Cite:Crystal structures of cytochrome P-450CAM complexed with camphane, thiocamphor, and adamantane: factors controlling P-450 substrate hydroxylation.
Biochemistry, 30, 1991
4DU2
DownloadVisualize
BU of 4du2 by Molmil
cytochrome P450 BM3h-B7 MRI sensor bound to dopamine
Descriptor: L-DOPAMINE, PROTOPORPHYRIN IX CONTAINING FE, cytochrome P450 BM3 variant B7
Authors:Brustad, E.M, Lelyveld, V.S, Snow, C.D, Crook, N, Martinez, F.M, Scholl, T.J, Jasanoff, A, Arnold, F.H.
Deposit date:2012-02-21
Release date:2012-06-13
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure-guided directed evolution of highly selective p450-based magnetic resonance imaging sensors for dopamine and serotonin.
J.Mol.Biol., 422, 2012
6G5O
DownloadVisualize
BU of 6g5o by Molmil
The structure of a carbohydrate active P450
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Robb, C.S, Hehemann, J.H.
Deposit date:2018-03-29
Release date:2018-11-21
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Specificity and mechanism of carbohydrate demethylation by cytochrome P450 monooxygenases.
Biochem. J., 475, 2018
6FSH
DownloadVisualize
BU of 6fsh by Molmil
Crystal structure of hybrid P450 OxyBtei(BC/FGvan)
Descriptor: ACETATE ION, OxyB protein, POTASSIUM ION, ...
Authors:Brieke, C, Tarnawski, M, Greule, A, Cryle, M.J.
Deposit date:2018-02-19
Release date:2018-05-23
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Investigating Cytochrome P450 specificity during glycopeptide antibiotic biosynthesis through a homologue hybridization approach.
J. Inorg. Biochem., 185, 2018
6FYJ
DownloadVisualize
BU of 6fyj by Molmil
Cytochrome P450 peroxygenase CYP152K6 in complex with Myristic Acid
Descriptor: DI(HYDROXYETHYL)ETHER, Fatty-acid peroxygenase, MYRISTIC ACID, ...
Authors:Girvan, H.M, Poddar, H, Mclean, K.J, Leys, D, Munro, A.W.
Deposit date:2018-03-12
Release date:2018-08-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Structural and catalytic properties of the peroxygenase P450 enzyme CYP152K6 from Bacillus methanolicus.
J. Inorg. Biochem., 188, 2018
6G71
DownloadVisualize
BU of 6g71 by Molmil
Structure of CYP1232A24 from Arthrobacter sp.
Descriptor: 1,2-ETHANEDIOL, Cytochrome P450, FE (III) ION, ...
Authors:Dubiel, P, Sharma, M, Klenk, J, Hauer, B, Grogan, G.
Deposit date:2018-04-04
Release date:2019-03-13
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Identification and characterization of cytochrome P450 1232A24 and 1232F1 from Arthrobacter sp. and their role in the metabolic pathway of papaverine.
J.Biochem., 166, 2019
6GEO
DownloadVisualize
BU of 6geo by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 10j
Descriptor: 2-chloranyl-3-[4-(imidazol-1-ylmethyl)-1-phenyl-pyrazol-3-yl]-1~{H}-indole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Levy, C.W.
Deposit date:2018-04-27
Release date:2019-08-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors.
Chemistryopen, 8, 2019
6GEQ
DownloadVisualize
BU of 6geq by Molmil
Crystal structure of Mycobacterium tuberculosis cytochrome P450 CYP121A1 in complex with Triazole Pyrazole inhibitor 14a
Descriptor: 1-phenyl-3-pyridin-4-yl-~{N}-(pyridin-4-ylmethyl)pyrazole-4-carboxamide, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Levy, C.W.
Deposit date:2018-04-27
Release date:2019-08-07
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Design and Synthesis of Imidazole and Triazole Pyrazoles asMycobacterium TuberculosisCYP121A1 Inhibitors.
Chemistryopen, 8, 2019
6GK5
DownloadVisualize
BU of 6gk5 by Molmil
Crystal structure of cytochrome P450 CYP267B1 from Sorangium cellulosum So ce56
Descriptor: Cytochrome P450 CYP267B1 protein, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2018-05-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1.
Biochem. J., 475, 2018
6H1O
DownloadVisualize
BU of 6h1o by Molmil
Structure of the BM3 heme domain in complex with voriconazole
Descriptor: 1,2-ETHANEDIOL, Bifunctional cytochrome P450/NADPH--P450 reductase, GLYCEROL, ...
Authors:Jeffreys, L.N, Munro, A.W.M, Leys, D.
Deposit date:2018-07-12
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.734 Å)
Cite:Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.
Sci Rep, 9, 2019
6HQP
DownloadVisualize
BU of 6hqp by Molmil
Crystal structure of GcoA F169V bound to guaiacol
Descriptor: Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE
Authors:Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E.
Deposit date:2018-09-25
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Enabling microbial syringol conversion through structure-guided protein engineering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HQS
DownloadVisualize
BU of 6hqs by Molmil
Crystal structure of GcoA F169S bound to syringol
Descriptor: 2,6-dimethoxyphenol, Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E.
Deposit date:2018-09-25
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Enabling microbial syringol conversion through structure-guided protein engineering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HN8
DownloadVisualize
BU of 6hn8 by Molmil
Structure of BM3 heme domain in complex with troglitazone
Descriptor: (5R)-5-(4-{[(2R)-6-HYDROXY-2,5,7,8-TETRAMETHYL-3,4-DIHYDRO-2H-CHROMEN-2-YL]METHOXY}BENZYL)-1,3-THIAZOLIDINE-2,4-DIONE, Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jeffreys, L, Munro, A.W.M, Leys, D.
Deposit date:2018-09-14
Release date:2019-10-09
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.997 Å)
Cite:Oxidation of antidiabetic compounds by cytochrome P450 BM3
To be published
6HQG
DownloadVisualize
BU of 6hqg by Molmil
Cytochrome P450-153 from Phenylobacterium zucineum
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fiorentini, F, Mattevi, A.
Deposit date:2018-09-25
Release date:2018-12-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.
Biochemistry, 57, 2018
6H1S
DownloadVisualize
BU of 6h1s by Molmil
Structure of the BM3 heme domain in complex with fluconazole
Descriptor: 1,2-ETHANEDIOL, 2-(2,4-DIFLUOROPHENYL)-1,3-DI(1H-1,2,4-TRIAZOL-1-YL)PROPAN-2-OL, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
Authors:Jeffreys, L.N, Munro, A.W.M, Leys, D.
Deposit date:2018-07-12
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.
Sci Rep, 9, 2019
6H1L
DownloadVisualize
BU of 6h1l by Molmil
Structure of the BM3 heme domain in complex with tioconazole
Descriptor: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, Bifunctional cytochrome P450/NADPH--P450 reductase, ...
Authors:Jeffreys, L.N, Munro, A.W.M, Leys, D.
Deposit date:2018-07-12
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.968 Å)
Cite:Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.
Sci Rep, 9, 2019
6H1T
DownloadVisualize
BU of 6h1t by Molmil
Structure of the BM3 heme domain in complex with clotrimazole
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1-[(2-CHLOROPHENYL)(DIPHENYL)METHYL]-1H-IMIDAZOLE, ...
Authors:Jeffreys, L.N, Munro, A.W.M, Leys, D.
Deposit date:2018-07-12
Release date:2019-02-20
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.08 Å)
Cite:Novel insights into P450 BM3 interactions with FDA-approved antifungal azole drugs.
Sci Rep, 9, 2019
6GK6
DownloadVisualize
BU of 6gk6 by Molmil
Crystal structure of myxobacterial cytochrome P450 CYP267B1 in complex with myristic acid
Descriptor: Cytochrome P450 CYP267B1 protein, MYRISTIC ACID, PROTOPORPHYRIN IX CONTAINING FE
Authors:Jozwik, I.K, Thunnissen, A.M.W.H.
Deposit date:2018-05-18
Release date:2018-08-08
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Structural insights into oxidation of medium-chain fatty acids and flavanone by myxobacterial cytochrome P450 CYP267B1.
Biochem. J., 475, 2018
6HQD
DownloadVisualize
BU of 6hqd by Molmil
Cytochrome P450-153 from Pseudomonas sp. 19-rlim
Descriptor: Cytochrome P450, GLYCEROL, PROTOPORPHYRIN IX CONTAINING FE, ...
Authors:Fiorentini, F, Mattevi, A.
Deposit date:2018-09-24
Release date:2018-12-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.
Biochemistry, 57, 2018
6HQN
DownloadVisualize
BU of 6hqn by Molmil
Crystal structure of GcoA F169L bound to guaiacol
Descriptor: Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE
Authors:Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E.
Deposit date:2018-09-25
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Enabling microbial syringol conversion through structure-guided protein engineering.
Proc.Natl.Acad.Sci.USA, 116, 2019
6HQW
DownloadVisualize
BU of 6hqw by Molmil
Cytochrome P450-153 from Novosphingobium aromaticivorans
Descriptor: Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE
Authors:Fiorentini, F, Mattevi, A.
Deposit date:2018-09-25
Release date:2018-12-12
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.
Biochemistry, 57, 2018
6HQO
DownloadVisualize
BU of 6hqo by Molmil
Crystal structure of GcoA F169S bound to guaiacol
Descriptor: Cytochrome P450, Guaiacol, PROTOPORPHYRIN IX CONTAINING FE
Authors:Mallinson, S.J.B, Hinchen, D.J, Allen, M.D, Johnson, C.W, Beckham, G.T, McGeehan, J.E.
Deposit date:2018-09-25
Release date:2019-07-03
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Enabling microbial syringol conversion through structure-guided protein engineering.
Proc.Natl.Acad.Sci.USA, 116, 2019

221716

PDB entries from 2024-06-26

PDB statisticsPDBj update infoContact PDBjnumon