3WEC
Structure of P450 RauA (CYP1050A1) complexed with a biosynthetic intermediate of aurachin RE
Summary for 3WEC
| Entry DOI | 10.2210/pdb3wec/pdb |
| Descriptor | Cytochrome P450, PROTOPORPHYRIN IX CONTAINING FE, 3-[(2E,6E,9R)-9-hydroxy-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]-2-methylquinolin-4(1H)-one, ... (4 entities in total) |
| Functional Keywords | p450 fold, monooxygenase (hydroxylase), heme, cytosolic enzyme, oxidoreductase |
| Biological source | Rhodococcus erythropolis |
| Total number of polymer chains | 1 |
| Total formula weight | 46912.48 |
| Authors | Yasutake, Y.,Kitagawa, W.,Tamura, T. (deposition date: 2013-07-03, release date: 2014-01-01, Last modification date: 2023-11-08) |
| Primary citation | Yasutake, Y.,Kitagawa, W.,Hata, M.,Nishioka, T.,Ozaki, T.,Nishiyama, M.,Kuzuyama, T.,Tamura, T. Structure of the quinoline N-hydroxylating cytochrome P450 RauA, an essential enzyme that confers antibiotic activity on aurachin alkaloids Febs Lett., 588:105-110, 2014 Cited by PubMed: 24269679DOI: 10.1016/j.febslet.2013.11.016 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.19 Å) |
Structure validation
Download full validation report
