5WBG

Crystal Structure of human Cytochrome P450 2B6 (Y226H/K262R) in complex with an analog of a drug Efavirenz

Summary for 5WBG

• Entry DOI: 10.2210/pdb5wbg/pdb
• Related: 3UA5 4I91 5UAP 5UDA 5UEC
• Descriptor: Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, (2R,4S)-6-chloro-4-(cyclopropylethynyl)-2-methyl-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazine, ... (6 entities in total)
• Functional Keywords: oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 336112.41

Authors

Shah, M.B.,Halpert, J.R. (deposition date: 2017-06-29, release date: 2018-05-02, Last modification date: 2023-10-04)

• Primary citation: Shah, M.B.,Zhang, Q.,Halpert, J.R.; Crystal Structure of CYP2B6 in Complex with an Efavirenz Analog.; Int J Mol Sci, 19:-, 2018; PubMed: 29596329; DOI: 10.3390/ijms19041025

Experimental method

X-RAY DIFFRACTION (2.99 Å)