5UAP

Crystal Structure of CYP2B6 (Y226H/K262R) in complex with Bornyl Bromide

Summary for 5UAP

• Entry DOI: 10.2210/pdb5uap/pdb
• Related: 5UDA 5UEC
• Descriptor: Cytochrome P450 2B6, PROTOPORPHYRIN IX CONTAINING FE, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, ... (5 entities in total)
• Functional Keywords: cytochrome p450, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 113926.71

Authors

Shah, M.B.,Halpert, J.R. (deposition date: 2016-12-19, release date: 2017-04-12, Last modification date: 2023-10-04)

• Primary citation: Shah, M.B.,Liu, J.,Zhang, Q.,Stout, C.D.,Halpert, J.R.; Halogen-pi Interactions in the Cytochrome P450 Active Site: Structural Insights into Human CYP2B6 Substrate Selectivity.; ACS Chem. Biol., 12:1204-1210, 2017; PubMed: 28368100; DOI: 10.1021/acschembio.7b00056

Experimental method

X-RAY DIFFRACTION (2.03 Å)