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PDB: 403 results

5PPR
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BU of 5ppr by Molmil
PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 28)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION
Authors:Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
Deposit date:2017-02-07
Release date:2017-03-29
Last modified:2017-10-04
Method:X-RAY DIFFRACTION (2.69 Å)
Cite:A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
5PW6
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BU of 5pw6 by Molmil
PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 257)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION
Authors:Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
Deposit date:2017-02-07
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
5BNV
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BU of 5bnv by Molmil
Crystal structure of Human MCM2 HBD chaperoning a histone H3-H4 tetramer
Descriptor: DNA replication licensing factor MCM2, Histone H3.3, Histone H4, ...
Authors:Huang, H, Patel, D.J.
Deposit date:2015-05-26
Release date:2015-06-17
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.
Nat.Struct.Mol.Biol., 22, 2015
4HGA
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BU of 4hga by Molmil
Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Liu, C.P, Xiong, C.Y, Wang, M.Z, Yu, Z.L, Yang, N, Chen, P, Zhang, Z.G, Li, G.H, Xu, R.M.
Deposit date:2012-10-07
Release date:2012-11-07
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.799 Å)
Cite:Structure of the variant histone H3.3-H4 heterodimer in complex with its chaperone DAXX.
Nat.Struct.Mol.Biol., 19, 2012
3AV2
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BU of 3av2 by Molmil
The human nucleosome structure containing the histone variant H3.3
Descriptor: 146-MER DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ...
Authors:Tachiwana, H, Osakabe, A, Shiga, T, Miya, M, Kimura, H, Kagawa, W, Kurumizaka, H.
Deposit date:2011-02-18
Release date:2011-06-01
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of human nucleosomes containing major histone H3 variants
Acta Crystallogr.,Sect.D, 67, 2011
7V1M
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BU of 7v1m by Molmil
Structural basis for the co-chaperone relationship of sNASP and ASF1b
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Bao, H, Huang, H.
Deposit date:2021-08-04
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.834 Å)
Cite:NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
7V1L
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BU of 7v1l by Molmil
Structure of sNASP core in complex with H3 alpha3 helix peptide
Descriptor: H3 alpha3 helix peptide, Isoform 2 of Nuclear autoantigenic sperm protein
Authors:Bao, H, Huang, H.
Deposit date:2021-08-04
Release date:2022-04-20
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.849 Å)
Cite:NASP maintains histone H3-H4 homeostasis through two distinct H3 binding modes.
Nucleic Acids Res., 50, 2022
4U7T
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BU of 4u7t by Molmil
Crystal structure of DNMT3A-DNMT3L in complex with histone H3
Descriptor: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
Authors:Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y.
Deposit date:2014-07-31
Release date:2014-11-12
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
3ASK
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BU of 3ask by Molmil
Structure of UHRF1 in complex with histone tail
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3.3, ZINC ION
Authors:Arita, K, Sugita, K, Unoki, M, Hamamoto, R, Sekiyama, N, Tochio, H, Ariyoshi, M, Shirakawa, M.
Deposit date:2010-12-16
Release date:2012-01-25
Last modified:2013-06-05
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Recognition of modification status on a histone H3 tail by linked histone reader modules of the epigenetic regulator UHRF1
Proc.Natl.Acad.Sci.USA, 109, 2012
5B33
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BU of 5b33 by Molmil
The crystal structure of the H2AZ nucleosome with H3.3.
Descriptor: DNA (146-MER), Histone H2A.Z, Histone H2B type 1-J, ...
Authors:Horikoshi, N, Taguchi, H, Arimura, Y, Kurumizaka, H.
Deposit date:2016-02-08
Release date:2016-08-03
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.925 Å)
Cite:Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A.
Open Biology, 6, 2016
4GY5
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BU of 4gy5 by Molmil
Crystal structure of the tandem tudor domain and plant homeodomain of UHRF1 with Histone H3K9me3
Descriptor: E3 ubiquitin-protein ligase UHRF1, Peptide from Histone H3.3, ZINC ION
Authors:Cheng, J, Yang, Y, Fang, J, Xiao, J, Zhu, T, Chen, F, Wang, P, Xu, Y.
Deposit date:2012-09-05
Release date:2012-11-14
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.956 Å)
Cite:Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein
J.Biol.Chem., 288, 2013
9B3P
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BU of 9b3p by Molmil
The cryo-EM structure of the H2A.Z-H3.3 double-variant nucleosome
Descriptor: DNA (128-MER), Histone H2A.Z, Histone H2B 1.1, ...
Authors:Tan, D, Sokolova, V.
Deposit date:2024-03-19
Release date:2024-06-12
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural and Biochemical Characterization of the Nucleosome Containing Variants H3.3 and H2A.Z.
Epigenomes, 8, 2024
7VCQ
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BU of 7vcq by Molmil
structure of viral protein BKRF4 in complex with H3.3-H4-ASF1
Descriptor: Histone H3.3, Histone H4, Histone chaperone ASF1B, ...
Authors:Liu, Y.R.
Deposit date:2021-09-03
Release date:2022-08-03
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (3 Å)
Cite:Epstein-Barr Virus Tegument Protein BKRF4 is a Histone Chaperone.
J.Mol.Biol., 434, 2022
5PVU
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BU of 5pvu by Molmil
PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 245)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION
Authors:Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
Deposit date:2017-02-07
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
6PZV
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BU of 6pzv by Molmil
Crystal Structure of Bovine DNMT1 RFTS domain in complex with H3K9me3 and Ubiquitin
Descriptor: CITRATE ANION, DNA (cytosine-5)-methyltransferase 1, Histone H3.3, ...
Authors:Ren, W, Song, J.
Deposit date:2019-08-01
Release date:2020-07-15
Last modified:2020-08-12
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Proc.Natl.Acad.Sci.USA, 117, 2020
4GU0
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BU of 4gu0 by Molmil
Crystal structure of LSD2 with H3
Descriptor: FLAVIN-ADENINE DINUCLEOTIDE, Histone H3.3, Lysine-specific histone demethylase 1B, ...
Authors:Chen, F, Yang, H, Dong, Z, Fang, J, Zhu, T, Gong, W, Xu, Y.
Deposit date:2012-08-29
Release date:2013-02-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.103 Å)
Cite:Structural insight into substrate recognition by histone demethylase LSD2/KDM1b
Cell Res., 23, 2013
7A08
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BU of 7a08 by Molmil
CryoEM Structure of cGAS Nucleosome complex
Descriptor: Cyclic GMP-AMP synthase, Histone H2A type 1-C, Histone H2B type 1-C/E/F/G/I, ...
Authors:Michalski, S, de Oliveira Mann, C.C, Witte, G, Bartho, J, Lammens, K, Hopfner, K.P.
Deposit date:2020-08-07
Release date:2020-09-23
Last modified:2021-02-10
Method:ELECTRON MICROSCOPY (3.11 Å)
Cite:Structural basis for sequestration and autoinhibition of cGAS by chromatin.
Nature, 587, 2020
8JH4
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BU of 8jh4 by Molmil
RNA polymerase II elongation complex containing 60 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023
7XSZ
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BU of 7xsz by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC115)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-15
Release date:2022-09-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
5PSH
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BU of 5psh by Molmil
PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 125)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION
Authors:Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
Deposit date:2017-02-07
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.43 Å)
Cite:A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
5PW9
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BU of 5pw9 by Molmil
PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 260)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION
Authors:Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
Deposit date:2017-02-07
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.44 Å)
Cite:A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
5KDM
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BU of 5kdm by Molmil
Crystal structure of EBV tegument protein BNRF1 in complex with histone chaperone DAXX and histones H3.3-H4
Descriptor: Death domain-associated protein 6, Histone H3.3, Histone H4, ...
Authors:Huang, H, Patel, D.
Deposit date:2016-06-08
Release date:2016-09-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Structural basis underlying viral hijacking of a histone chaperone complex.
Nat Commun, 7, 2016
5PRM
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BU of 5prm by Molmil
PanDDA analysis group deposition -- Crystal Structure of BRD1 after initial refinement with no ligand modelled (structure 94)
Descriptor: 1,2-ETHANEDIOL, Bromodomain-containing protein 1, SODIUM ION
Authors:Pearce, N.M, Krojer, T, Talon, R, Bradley, A.R, Fairhead, M, Sethi, R, Wright, N, MacLean, E, Collins, P, Brandao-Neto, J, Douangamath, A, Renjie, Z, Dias, A, Ng, J, Brennan, P.E, Cox, O, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F.
Deposit date:2017-02-07
Release date:2017-03-29
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.58 Å)
Cite:A multi-crystal method for extracting obscured crystallographic states from conventionally uninterpretable electron density.
Nat Commun, 8, 2017
7XSE
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BU of 7xse by Molmil
RNA polymerase II elongation complex transcribing a nucleosome (EC42)
Descriptor: Component of the Paf1p complex, Constituent of Paf1 complex with RNA polymerase II, Paf1p, ...
Authors:Ehara, H, Kujirai, T, Shirouzu, M, Kurumizaka, H, Sekine, S.
Deposit date:2022-05-13
Release date:2022-09-07
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structural basis of nucleosome disassembly and reassembly by RNAPII elongation complex with FACT.
Science, 377, 2022
8JH3
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BU of 8jh3 by Molmil
RNA polymerase II elongation complex containing 40 bp upstream DNA loop, stalled at SHL(-1) of the nucleosome
Descriptor: DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ...
Authors:Akatsu, M, Fujita, R, Ogasawara, M, Ehara, H, Kujirai, T, Takizawa, Y, Sekine, S, Kurumizaka, H.
Deposit date:2023-05-22
Release date:2023-11-29
Last modified:2023-12-20
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Cryo-EM structures of RNA polymerase II-nucleosome complexes rewrapping transcribed DNA.
J.Biol.Chem., 299, 2023

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