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PDB: 260 results

5V02
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BU of 5v02 by Molmil
A positive allosteric modulator binding pocket in SK2 ion channels is shared by Riluzole and CyPPA
Descriptor: 6-(trifluoromethoxy)-1,3-benzothiazol-2-amine, CALCIUM ION, Calmodulin-1, ...
Authors:Liu, S.
Deposit date:2017-02-28
Release date:2018-03-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes.
Structure, 26, 2018
4BW8
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BU of 4bw8 by Molmil
Calmodulin with small bend in central helix
Descriptor: CALCIUM ION, CALMODULIN
Authors:Kursula, P.
Deposit date:2013-06-30
Release date:2014-01-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystallographic Snapshots of Initial Steps in the Collapse of the Calmodulin Central Helix
Acta Crystallogr.,Sect.D, 70, 2014
2Y4V
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BU of 2y4v by Molmil
CRYSTAL STRUCTURE OF HUMAN CALMODULIN IN COMPLEX WITH A DAP KINASE-1 MUTANT (W305Y) PEPTIDE
Descriptor: CALCIUM ION, CALMODULIN, DEATH-ASSOCIATED PROTEIN KINASE 1,
Authors:de Diego, I, Lehmann, F, Wilmanns, M.
Deposit date:2011-01-11
Release date:2011-12-28
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:A Journey Through the Dap Kinase Architecture
To be Published
5JQA
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BU of 5jqa by Molmil
CaM:RM20 complex
Descriptor: CALCIUM ION, Calmodulin, Myosin light chain kinase, ...
Authors:Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M.
Deposit date:2016-05-04
Release date:2017-10-11
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:CaM:RM20 complex
To be Published
4Q57
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BU of 4q57 by Molmil
Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Song, J.-G, Kostan, J, Grishkovskaya, I, Djinovic-Carugo, K.
Deposit date:2014-04-16
Release date:2014-07-23
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of the plectin 1a actin-binding domain/N-terminal domain of calmodulin complex
To be Published
3UCY
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BU of 3ucy by Molmil
Structure of Mg2+ bound N-terminal domain of calmodulin in the presence of Zn2+
Descriptor: CACODYLATE ION, Calmodulin, MAGNESIUM ION, ...
Authors:Senguen, F.T, Grabarek, Z.
Deposit date:2011-10-27
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand.
Biochemistry, 51, 2012
4BW7
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BU of 4bw7 by Molmil
Calmodulin in complex with strontium
Descriptor: CALMODULIN, STRONTIUM ION
Authors:Kursula, P.
Deposit date:2013-06-30
Release date:2014-01-15
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Crystallographic Snapshots of Initial Steps in the Collapse of the Calmodulin Central Helix
Acta Crystallogr.,Sect.D, 70, 2014
6Y4O
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BU of 6y4o by Molmil
Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain
Descriptor: CALCIUM ION, Calmodulin-2, Ryanodine receptor 2
Authors:Lau, K, Nielsen, L.H, Holt, C, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Van Petegem, F, Overgaard, M.T, Wimmer, R.
Deposit date:2020-02-21
Release date:2020-04-29
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.83549082 Å)
Cite:The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
5JTH
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BU of 5jth by Molmil
Crystal structure of E67A calmodulin - CaM:RM20 analog complex
Descriptor: CALCIUM ION, Calmodulin, Myosin light chain kinase, ...
Authors:Grum-Tokars, V.L, Minasov, G, Anderson, W.F, Watterson, D.M.
Deposit date:2016-05-09
Release date:2017-07-19
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:Crystal structure of E67A calmodulin - CaM:RM20 analog complex
To Be Published
3BYA
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BU of 3bya by Molmil
Structure of a Calmodulin Complex
Descriptor: CALCIUM ION, Calmodulin, Glutamate [NMDA] receptor subunit zeta-1 peptide
Authors:Birrane, G, Soni, A, Ladias, J.A.A.
Deposit date:2008-01-15
Release date:2009-01-20
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structure of a Calmodulin Complex
To be Published
2R28
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BU of 2r28 by Molmil
The complex Structure of Calmodulin Bound to a Calcineurin Peptide
Descriptor: CALCIUM ION, Calmodulin, Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform
Authors:Ye, Q, Zheng, J, Jia, Z.
Deposit date:2007-08-24
Release date:2008-07-01
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:The complex structure of calmodulin bound to a calcineurin peptide.
Proteins, 73, 2008
7WR3
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BU of 7wr3 by Molmil
Crystal structure of MBP-fused OspC3 in complex with calmodulin
Descriptor: Calmodulin-1, MBP-fused OspC3, NICOTINAMIDE, ...
Authors:Hou, Y.J, Zeng, H, Shao, F, Ding, J.
Deposit date:2022-01-26
Release date:2023-01-25
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.87 Å)
Cite:Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis.
Nat.Struct.Mol.Biol., 30, 2023
6O5G
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BU of 6o5g by Molmil
Calmodulin in complex with isomalbrancheamide D
Descriptor: (5aS,12aS,13aS)-9-bromo-8-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7 ,6-b]carbazol-14-one, CALCIUM ION, Calmodulin-1, ...
Authors:Beyett, T.S, Fraley, A.E, Tesmer, J.J.G.
Deposit date:2019-03-02
Release date:2019-08-07
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe.
Proc.Natl.Acad.Sci.USA, 116, 2019
7PSZ
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BU of 7psz by Molmil
Crystal structure of CaM in complex with CDZ (form 1)
Descriptor: 1-[bis(4-chlorophenyl)methyl]-3-[(2~{R})-2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole, CALCIUM ION, Calmodulin-1, ...
Authors:Mechaly, A.E, Leger, C, Haouz, A, Chenal, A.
Deposit date:2021-09-24
Release date:2022-08-17
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.898 Å)
Cite:Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium.
Bmc Biol., 20, 2022
6MUE
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BU of 6mue by Molmil
Voltage-gated sodium channel NaV1.4 IQ domain in complex with Ca2+/Calmodulin
Descriptor: CALCIUM ION, Calmodulin-1, Sodium channel protein type 4 subunit alpha
Authors:Gardill, B.R, Van Petegem, F.
Deposit date:2018-10-23
Release date:2019-05-08
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structures of Ca2+-calmodulin bound to NaVC-terminal regions suggest role for EF-hand domain in binding and inactivation.
Proc.Natl.Acad.Sci.USA, 116, 2019
2WEL
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BU of 2wel by Molmil
Crystal structure of SU6656-bound calcium/calmodulin-dependent protein kinase II delta in complex with calmodulin
Descriptor: (3Z)-N,N-DIMETHYL-2-OXO-3-(4,5,6,7-TETRAHYDRO-1H-INDOL-2-YLMETHYLIDENE)-2,3-DIHYDRO-1H-INDOLE-5-SULFONAMIDE, 1,2-ETHANEDIOL, CALCIUM ION, ...
Authors:Pike, A.C.W, Rellos, P, Salah, E, Burgess-Brown, N, Keates, T, Muniz, J, Sethi, R, Roos, A, Filippakopoulos, P, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Bountra, C, Knapp, S.
Deposit date:2009-03-31
Release date:2009-04-14
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation.
Plos Biol., 8, 2010
5WBX
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BU of 5wbx by Molmil
Structural insights into the potency of SK/IK channel positive modulators
Descriptor: (3Z)-6-bromo-3-(hydroxyimino)-5-methyl-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-1, ...
Authors:Nam, Y.W, Zhang, M.
Deposit date:2017-06-29
Release date:2017-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural insights into the potency of SK channel positive modulators.
Sci Rep, 7, 2017
3UCT
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BU of 3uct by Molmil
Structure of Mn2+-bound N-terminal domain of calmodulin in the presence of Zn2+
Descriptor: Calmodulin, MANGANESE (II) ION, ZINC ION
Authors:Senguen, F.T, Grabarek, Z.
Deposit date:2011-10-27
Release date:2012-08-08
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:X-ray Structures of Magnesium and Manganese Complexes with the N-Terminal Domain of Calmodulin: Insights into the Mechanism and Specificity of Metal Ion Binding to an EF-Hand.
Biochemistry, 51, 2012
6HR1
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BU of 6hr1 by Molmil
Crystal structure of the YFPnano fusion protein
Descriptor: 1,2-ETHANEDIOL, CALCIUM ION, GLYCEROL, ...
Authors:Benoit, R.M.
Deposit date:2018-09-26
Release date:2020-04-08
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (1.901 Å)
Cite:Chimeric single alpha-helical domains as rigid fusion protein connections for protein nanotechnology and structural biology.
Structure, 2021
1ZUZ
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BU of 1zuz by Molmil
Calmodulin in complex with a mutant peptide from human DRP-1 kinase
Descriptor: CALCIUM ION, DRP-1 kinase, calmodulin
Authors:Kursula, P, Vahokoski, J, Wilmanns, M.
Deposit date:2005-06-01
Release date:2006-11-14
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.91 Å)
Cite:Recognition of human death-associated protein kinases by calmodulin
To be Published
5DSU
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BU of 5dsu by Molmil
Crystal structure of double mutant of N-domain of human calmodulin
Descriptor: CALCIUM ION, Calmodulin, TRIETHYLENE GLYCOL
Authors:Ababou, A, Zaleska, M.
Deposit date:2015-09-17
Release date:2017-01-11
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:On the Ca(2+) binding and conformational change in EF-hand domains: Experimental evidence of Ca(2+)-saturated intermediates of N-domain of calmodulin.
Biochim. Biophys. Acta, 1865, 2017
2VAY
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BU of 2vay by Molmil
Calmodulin complexed with CaV1.1 IQ peptide
Descriptor: CALCIUM ION, CALMODULIN, CHLORIDE ION, ...
Authors:Halling, D.B, Black, D.J, Pedersen, S.E, Hamilton, S.L.
Deposit date:2007-09-05
Release date:2008-09-16
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.94 Å)
Cite:Determinants in Cav1 Channels that Regulate the Ca2+ Sensitivity of Bound Calmodulin.
J.Biol.Chem., 284, 2009
3SUI
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BU of 3sui by Molmil
Crystal structure of ca2+-calmodulin in complex with a trpv1 c-terminal peptide
Descriptor: CALCIUM ION, Calmodulin, SULFATE ION, ...
Authors:Lau, S.-Y, Gaudet, R.
Deposit date:2011-07-11
Release date:2012-09-12
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Distinct properties of Ca2+-calmodulin binding to N- and C-terminal regulatory regions of the TRPV1 channel.
J.Gen.Physiol., 140, 2012
7VUU
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BU of 7vuu by Molmil
Crystal structure of AlleyCat10 with inhibitor
Descriptor: 5-nitro-1H-benzotriazole, AlleyCat, CALCIUM ION
Authors:Tame, J.R.H, Korendovych, I.V, Margheritis, E, Takahashi, K.
Deposit date:2021-11-04
Release date:2022-07-27
Last modified:2024-05-29
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:NMR-guided directed evolution.
Nature, 610, 2022
7T2Q
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BU of 7t2q by Molmil
PEGylated Calmodulin-1 (K148U)
Descriptor: CALCIUM ION, Calmodulin-1, MAGNESIUM ION, ...
Authors:Mackay, J.P, Payne, R.J, Patel, K, Dowman, L.J.
Deposit date:2021-12-06
Release date:2022-10-26
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Site-selective photocatalytic functionalization of peptides and proteins at selenocysteine.
Nat Commun, 13, 2022

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