6O5G

Calmodulin in complex with isomalbrancheamide D

Summary for 6O5G

Entry DOI	10.2210/pdb6o5g/pdb
Descriptor	Calmodulin-1, (5aS,12aS,13aS)-9-bromo-8-chloro-12,12-dimethyl-2,3,11,12,12a,13-hexahydro-1H,5H,6H-5a,13a-(epiminomethano)indolizino[7 ,6-b]carbazol-14-one, CALCIUM ION, ... (5 entities in total)
Functional Keywords	ef hand, metal binding protein
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	17799.31
Authors	Beyett, T.S.,Fraley, A.E.,Tesmer, J.J.G. (deposition date: 2019-03-02, release date: 2019-08-07, Last modification date: 2023-10-11)
Primary citation	Beyett, T.S.,Fraley, A.E.,Labudde, E.,Patra, D.,Coleman, R.C.,Eguchi, A.,Glukhova, A.,Chen, Q.,Williams, R.M.,Koch, W.J.,Sherman, D.H.,Tesmer, J.J.G. Perturbation of the interactions of calmodulin with GRK5 using a natural product chemical probe. Proc.Natl.Acad.Sci.USA, 116:15895-15900, 2019 Cited by PubMed: 31337679 DOI: 10.1073/pnas.1818547116 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.89 Å)

Structure validation