7B5L
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 | Descriptor: | 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-04 | Release date: | 2021-02-10 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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5OHM
| K33-specific affimer bound to K33 diUb | Descriptor: | K33-specific affimer, POLYETHYLENE GLYCOL (N=34), Polyubiquitin-C | Authors: | Michel, M.A, Komander, D. | Deposit date: | 2017-07-17 | Release date: | 2017-10-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling. Mol. Cell, 68, 2017
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6TNF
| Structure of monoubiquitinated FANCD2 in complex with FANCI and DNA | Descriptor: | DNA (33-MER), FANCD2, Fanconi anemia complementation group I, ... | Authors: | Alcon, P, Shakeel, S, Passmore, L.A. | Deposit date: | 2019-12-07 | Release date: | 2020-02-19 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | FANCD2-FANCI is a clamp stabilized on DNA by monoubiquitination of FANCD2 during DNA repair. Nat.Struct.Mol.Biol., 27, 2020
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4DDI
| Crystal structure of human OTUB1/UbcH5b~Ub/Ub | Descriptor: | Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 D2, Ubiquitin thioesterase OTUB1 | Authors: | Juang, Y.C, Sanches, M, Sicheri, F. | Deposit date: | 2012-01-18 | Release date: | 2012-02-22 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (3.802 Å) | Cite: | OTUB1 Co-opts Lys48-Linked Ubiquitin Recognition to Suppress E2 Enzyme Function. Mol.Cell, 45, 2012
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6VAF
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7B5M
| Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 | Descriptor: | Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... | Authors: | Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. | Deposit date: | 2020-12-05 | Release date: | 2021-02-17 | Last modified: | 2021-03-10 | Method: | ELECTRON MICROSCOPY (3.91 Å) | Cite: | Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
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7TV4
| Crystal structure of NEMO CoZi in complex with HOIP NZF1 and linear diubiquitin | Descriptor: | E3 ubiquitin-protein ligase RNF31, NF-kappa-B essential modulator, Polyubiquitin-C, ... | Authors: | Rahighi, S, Iyer, M, Oveisi, H. | Deposit date: | 2022-02-03 | Release date: | 2022-08-17 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | Structural basis for the simultaneous recognition of NEMO and acceptor ubiquitin by the HOIP NZF1 domain. Sci Rep, 12, 2022
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6WJD
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5A5B
| Structure of the 26S proteasome-Ubp6 complex | Descriptor: | 26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOG, 26S PROTEASE REGULATORY SUBUNIT 6A, 26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOG, ... | Authors: | Aufderheide, A, Beck, F, Stengel, F, Hartwig, M, Schweitzer, A, Pfeifer, G, Goldberg, A.L, Sakata, E, Baumeister, W, Foerster, F. | Deposit date: | 2015-06-17 | Release date: | 2015-07-22 | Last modified: | 2017-08-30 | Method: | ELECTRON MICROSCOPY (9.5 Å) | Cite: | Structural Characterization of the Interaction of Ubp6 with the 26S Proteasome. Proc.Natl.Acad.Sci.USA, 112, 2015
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1GJZ
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2K8C
| Solution structure of PLAA family ubiquitin binding domain (PFUC) trans isomer in complex with ubiquitin | Descriptor: | Phospholipase A-2-activating protein, Ubiquitin | Authors: | Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y. | Deposit date: | 2008-09-04 | Release date: | 2009-05-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein. J.Biol.Chem., 284, 2009
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2K6D
| CIN85 Sh3-C domain in complex with ubiquitin | Descriptor: | SH3 domain-containing kinase-binding protein 1, Ubiquitin | Authors: | Forman-Kay, J, Bezsonova, I. | Deposit date: | 2008-07-07 | Release date: | 2008-08-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Interactions between the three CIN85 SH3 domains and ubiquitin: implications for CIN85 ubiquitination. Biochemistry, 47, 2008
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1D3Z
| UBIQUITIN NMR STRUCTURE | Descriptor: | PROTEIN (UBIQUITIN) | Authors: | Cornilescu, G, Marquardt, J.L, Ottiger, M, Bax, A. | Deposit date: | 1999-10-01 | Release date: | 1999-10-14 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Validation of Protein Structure from Anisotropic Carbonyl Chemical Shifts in a Dilute Liquid Crystalline Phase J.Am.Chem.Soc., 120, 1998
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2KJH
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2KDF
| NMR structure of minor S5a (196-306):K48 linked diubiquitin species | Descriptor: | 26S proteasome non-ATPase regulatory subunit 4, Ubiquitin | Authors: | Zhang, N, Wang, Q, Ehlinger, A, Randles, L, Lary, J.W, Kang, Y, Haririnia, A, Cole, J.L, Fushman, D, Walters, K.J. | Deposit date: | 2009-01-06 | Release date: | 2009-09-01 | Last modified: | 2022-03-16 | Method: | SOLUTION NMR | Cite: | Structure of the s5a:k48-linked diubiquitin complex and its interactions with rpn13. Mol.Cell, 35, 2009
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2K8B
| Solution structure of PLAA family ubiquitin binding domain (PFUC) cis isomer in complex with ubiquitin | Descriptor: | Phospholipase A-2-activating protein, Ubiquitin | Authors: | Fu, Q.S, Zhou, C.J, Gao, H.C, Lin, D.H, Hu, H.Y. | Deposit date: | 2008-09-04 | Release date: | 2009-05-05 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Structural Basis for Ubiquitin Recognition by a Novel Domain from Human Phospholipase A2-activating Protein. J.Biol.Chem., 284, 2009
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6N13
| UbcH7-Ub Complex with R0RBR Parkin and phosphoubiquitin | Descriptor: | E3 ubiquitin-protein ligase parkin, Ubiquitin-conjugating enzyme E2 L3, ZINC ION, ... | Authors: | Condos, T.E.C, Dunkerley, K.M, Freeman, E.A, Barber, K.R, Aguirre, J.D, Chaugule, V.K, Xiao, Y, Konermann, L, Walden, H, Shaw, G.S. | Deposit date: | 2018-11-08 | Release date: | 2018-11-28 | Last modified: | 2020-01-08 | Method: | SOLUTION NMR | Cite: | Synergistic recruitment of UbcH7~Ub and phosphorylated Ubl domain triggers parkin activation. EMBO J., 37, 2018
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2KX0
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2KLG
| PERE NMR structure of ubiquitin | Descriptor: | Ubiquitin | Authors: | Madl, T, Bermel, W, Zangger, K. | Deposit date: | 2009-07-02 | Release date: | 2009-10-06 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Use of Relaxation Enhancements in a Paramagnetic Environment for the Structure Determination of Proteins Using NMR Spectroscopy Angew.Chem.Int.Ed.Engl., 48, 2009
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2KN5
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2LVO
| Structure of the gp78CUE domain bound to monubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2LVP
| gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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2RU6
| The pure alternative state of ubiquitin | Descriptor: | Ubiquitin | Authors: | Kitazawa, S, Kameda, T, Kumo, A, Utsumi, M, Baxter, N, Kato, K, Williamson, M.P, Kitahara, R. | Deposit date: | 2013-12-04 | Release date: | 2014-02-12 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Close Identity between Alternatively Folded State N2 of Ubiquitin and the Conformation of the Protein Bound to the Ubiquitin-Activating Enzyme Biochemistry, 53, 2014
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2FUH
| Solution Structure of the UbcH5c/Ub Non-covalent Complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 D3 | Authors: | Brzovic, P.S, Lissounov, A, Hoyt, D.W, Klevit, R.E. | Deposit date: | 2006-01-26 | Release date: | 2006-03-28 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | A UbcH5/Ubiquitin Noncovalent Complex Is Required for Processive BRCA1-Directed Ubiquitination. Mol.Cell, 21, 2006
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2LVQ
| gp78CUE domain bound to the proximal ubiquitin of K48-linked diubiquitin | Descriptor: | E3 ubiquitin-protein ligase AMFR, Ubiquitin | Authors: | Liu, S, Chen, Y, Huang, T, Tarasov, S.G, King, A, Li, J, Weissman, A.M, Byrd, R.A, Das, R. | Deposit date: | 2012-07-09 | Release date: | 2012-11-21 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains. Structure, 20, 2012
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