gp78CUE domain bound to the distal ubiquitin of K48-linked diubiquitin

Summary for 2LVP

Related2LVN 2LVO 2LVQ
DescriptorUbiquitin, E3 ubiquitin-protein ligase AMFR (2 entities in total)
Functional Keywordscue domain, signaling protein-ligase complex, signaling protein/ligase
Biological sourceHomo sapiens (human)
Cellular locationUbiquitin: Cytoplasm (By similarity) P0CG48
Endoplasmic reticulum membrane; Multi-pass membrane protein Q9UKV5
Total number of polymer chains3
Total molecular weight23120.41
Liu, S.,Chen, Y.,Huang, T.,Tarasov, S.G.,King, A.,Li, J.,Weissman, A.M.,Byrd, R.A.,Das, R. (deposition date: 2012-07-09, release date: 2012-11-21, Last modification date: 2012-12-26)
Primary citation
Liu, S.,Chen, Y.,Li, J.,Huang, T.,Tarasov, S.,King, A.,Weissman, A.M.,Byrd, R.A.,Das, R.
Promiscuous Interactions of gp78 E3 Ligase CUE Domain with Polyubiquitin Chains.
Structure, 20:2138-2150, 2012
PubMed: 23123110 (PDB entries with the same primary citation)
DOI: 10.1016/j.str.2012.09.020
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliers10.1%9.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all NMR structures
Download full validation report