8DVR
 
 | | Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+AMPPNP) | | Descriptor: | Antiviral innate immune response receptor RIG-I, GUANOSINE-5'-TRIPHOSPHATE, ZINC ION, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-07-29 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-12 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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4P4H
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7BAI
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8SCZ
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7TO0
 | | Cryo-EM structure of RIG-I in complex with OHdsRNA | | Descriptor: | Antiviral innate immune response receptor RIG-I, OHdsRNA, ZINC ION | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-01-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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7TNZ
 | | Cryo-EM structure of RIG-I in complex with p1dsRNA | | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p1dsRNA | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-01-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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7TNX
 | | Cryo-EM structure of RIG-I in complex with p3dsRNA | | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3dsRNAa, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-01-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.54 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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7TO1
 | | Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+ATP) | | Descriptor: | Antiviral innate immune response receptor RIG-I, ZINC ION, p3SLR30 | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2022-01-22 | | Release date: | 2022-11-02 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.
Mol.Cell, 82, 2022
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4NQK
 | | Structure of an Ubiquitin complex | | Descriptor: | Probable ATP-dependent RNA helicase DDX58, Ubiquitin | | Authors: | Peisley, A, Wu, B, Hur, S. | | Deposit date: | 2013-11-25 | | Release date: | 2014-03-05 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (3.7 Å) | | Cite: | Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I.
Nature, 509, 2014
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8SD0
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8G7V
 | | Cryo-EM structure of Riplet:RIG-I:dsRNA complex (end-inter) | | Descriptor: | Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ZINC ION, ... | | Authors: | Wang, W, Pyle, A.M. | | Deposit date: | 2023-02-17 | | Release date: | 2023-11-15 | | Last modified: | 2024-05-29 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | The E3 ligase Riplet promotes RIG-I signaling independent of RIG-I oligomerization.
Nat Commun, 14, 2023
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7JL1
 | | Cryo-EM structure of RIG-I:dsRNA in complex with RIPLET PrySpry domain (monomer) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... | | Authors: | Kato, K, Ahmad, S, Hur, S. | | Deposit date: | 2020-07-29 | | Release date: | 2020-12-09 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.
Mol.Cell, 81, 2021
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8G7U
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7JL3
 | | Cryo-EM structure of RIG-I:dsRNA filament in complex with RIPLET PrySpry domain (trimer) | | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Antiviral innate immune response receptor RIG-I, E3 ubiquitin-protein ligase RNF135, ... | | Authors: | Kato, K, Ahmad, S, Hur, S. | | Deposit date: | 2020-07-29 | | Release date: | 2020-12-09 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | Structural analysis of RIG-I-like receptors reveals ancient rules of engagement between diverse RNA helicases and TRIM ubiquitin ligases.
Mol.Cell, 81, 2021
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2RMJ
 | | Solution structure of RIG-I C-terminal domain | | Descriptor: | Probable ATP-dependent RNA helicase DDX58 | | Authors: | Takahasi, K, Yoneyama, M, Nihishori, T, Hirai, R, Narita, R, Gale Jr, M, Fujita, T, Inagaki, F. | | Deposit date: | 2007-10-23 | | Release date: | 2008-03-25 | | Last modified: | 2024-05-29 | | Method: | SOLUTION NMR | | Cite: | Nonself RNA-Sensing Mechanism of RIG-I Helicase and Activation of Antiviral Immune Responses
Mol.Cell, 29, 2008
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2LWD
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2LWE
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