7BAI

Structure of RIG-I CTD (I875A) bound to p-RNA

Summary for 7BAI

• Entry DOI: 10.2210/pdb7bai/pdb
• Descriptor: Antiviral innate immune response receptor RIG-I, RNA (5'-R(*(GDP)P*AP*CP*GP*CP*UP*AP*GP*CP*GP*UP*C)-3'), ZINC ION (3 entities in total)
• Functional Keywords: rna recognition, innate immunity, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 56479.76

Authors

Anand, K.,Hagelueken, G.,Fusshoeller, D.,Geyer, M. (deposition date: 2020-12-15, release date: 2022-01-12, Last modification date: 2024-01-31)

• Primary citation: de Regt, A.K.,Anand, K.,Gatterdam, K.,Hagelueken, G.,Hartmann, G.,Geyer, M.,Schlee, M.; A conserved isoleucine in the RNA sensor RIG-I controls immune tolerance to mitochondrial RNA; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.4 Å)