8DVR

Cryo-EM structure of RIG-I bound to the end of p3SLR30 (+AMPPNP)

Summary for 8DVR

• Entry DOI: 10.2210/pdb8dvr/pdb
• EMDB information: 27743
• Descriptor: Antiviral innate immune response receptor RIG-I, p3SLR30, ZINC ION, ... (4 entities in total)
• Functional Keywords: ribonucleoprotein complex, rna sensor, rig-i like receptor, hydrolase-rna complex, hydrolase/rna
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 126842.72

Authors

Wang, W.,Pyle, A.M. (deposition date: 2022-07-29, release date: 2022-11-02, Last modification date: 2022-11-16)

• Primary citation: Wang, W.,Pyle, A.M.; The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.; Mol.Cell, 82:4131-, 2022; PubMed: 36272408; DOI: 10.1016/j.molcel.2022.09.029

Experimental method

ELECTRON MICROSCOPY (3.3 Å)