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PDB: 47 results

5VTX
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BU of 5vtx by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225M/L226T/S228A mutant apo form
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-18
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
7RDH
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BU of 7rdh by Molmil
Crystal structure of the de novo designed binding protein H3mb in complex with the 1968 influenza A virus hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, De novo designed protein H3mb, ...
Authors:Kadam, R.U, Wilson, I.A.
Deposit date:2021-07-09
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Design of protein-binding proteins from the target structure alone.
Nature, 605, 2022
5KAN
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BU of 5kan by Molmil
Crystal structure of multidonor HV1-18-class broadly neutralizing Influenza A antibody 16.g.07 in complex with A/Hong Kong/1-4-MA21-1/1968 (H3N2) Hemagglutinin
Descriptor: 16.g.07 Heavy chain, 16.g.07 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
Deposit date:2016-06-01
Release date:2016-11-30
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.785 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell(Cambridge,Mass.), 166, 2016
7K37
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BU of 7k37 by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 7.8
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Xiang, Y, Gao, J.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (2.8 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
3SDY
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BU of 3sdy by Molmil
Crystal Structure of Broadly Neutralizing Antibody CR8020 Bound to the Influenza A H3 Hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8020, Heavy Chain, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2011-06-09
Release date:2011-07-20
Last modified:2021-04-07
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A highly conserved neutralizing epitope on group 2 influenza A viruses.
Science, 333, 2011
6WXB
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BU of 6wxb by Molmil
Cryo-EM Structure of Influenza Hemagglutinin (HA) Trimer Vitrified Using Back-it-up
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, beta-D-mannopyranose
Authors:Tan, Y.Z, Rubinstein, J.L.
Deposit date:2020-05-10
Release date:2020-05-20
Last modified:2020-11-18
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Through-grid wicking enables high-speed cryoEM specimen preparation.
Acta Crystallogr D Struct Biol, 76, 2020
4FP8
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BU of 4fp8 by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin, HA1 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-21
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.947 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
6NZ7
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BU of 6nz7 by Molmil
Crystal structure of broadly neutralizing Influenza A antibody 429 B01 in complex with Hemagglutinin Hong Kong 1968
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 429 B01 FAB heavy chain, 429 B01 FAB light chain, ...
Authors:Zhou, T, Kwong, P.D.
Deposit date:2019-02-13
Release date:2019-05-08
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Prolonged evolution of the memory B cell response induced by a replicating adenovirus-influenza H5 vaccine.
Sci Immunol, 4, 2019
5VTQ
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BU of 5vtq by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225L/L226S mutant in complex with 3'-SLN
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2017-05-17
Release date:2017-06-28
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.95 Å)
Cite:Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin.
Cell Host Microbe, 21, 2017
5K9K
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BU of 5k9k by Molmil
Crystal structure of multidonor HV6-1-class broadly neutralizing Influenza A antibody 56.a.09 in complex with Hemagglutinin Hong Kong 1968.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 56.a.09 Heavy chain, ...
Authors:Joyce, M.G, Thomas, P.V, Wheatley, A.K, McDermott, A.B, Mascola, J.R, Kwong, P.D.
Deposit date:2016-05-31
Release date:2016-12-21
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses.
Cell, 166, 2016
7K39
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BU of 7k39 by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation A, neutral pH-like
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Gao, J, Xiang, Y.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
4ZCJ
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BU of 4zcj by Molmil
Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin HA1 Cys30, HA2 Cys47 mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2015-04-16
Release date:2015-05-13
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3 Å)
Cite:Design and Structure of an Engineered Disulfide-Stabilized Influenza Virus Hemagglutinin Trimer.
J.Virol., 89, 2015
6D0U
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BU of 6d0u by Molmil
Crystal structure of C05 V110P/A117E mutant bound to H3 influenza hemagglutinin, HA1 subunit
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody C05 V110P/A117E mutant, heavy chain, ...
Authors:Wu, N.C, Wilson, I.A.
Deposit date:2018-04-11
Release date:2019-01-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Multistate design of influenza antibodies improves affinity and breadth against seasonal viruses.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
8PK3
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BU of 8pk3 by Molmil
CryoEM reconstruction of hemagglutinin HK68 of Influenza A virus bound to an Affimer reagent
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Affimer molecule (A31), ...
Authors:Debski-Antoniak, O, Flynn, A, Klebl, D.P, Tiede, C, Muench, S, Tomlinson, D, Fontana, J.
Deposit date:2023-06-24
Release date:2024-01-03
Last modified:2024-05-29
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Exploiting the Affimer platform against influenza A virus
To Be Published
7K3B
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BU of 7k3b by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation C, central helices splay
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Gao, J, Xiang, Y.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (3.4 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
3ZTJ
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BU of 3ztj by Molmil
Structure of influenza A neutralizing antibody selected from cultures of single human plasma cells in complex with human H3 Influenza haemagglutinin.
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FI6V3 ANTIBODY HEAVY CHAIN, ...
Authors:Voss, J.E, Vachieri, S.G, Gamblin, S.J, Collins, P.J, Haire, L.F, Skehel, J.J.
Deposit date:2011-07-08
Release date:2011-08-10
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (3.41 Å)
Cite:A Neutralizing Antibody Selected from Plasma Cells that Binds to Group 1 and Group 2 Influenza a Hemagglutinins.
Science, 333, 2011
4UBD
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BU of 4ubd by Molmil
Crystal structure of a neutralizing human monoclonal antibody with 1968 H3 HA
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin HA1 chain, ...
Authors:Shore, D.A, Yang, H, Cho, M, Donis, R.O, Stevens, J.
Deposit date:2014-08-12
Release date:2015-06-24
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus.
Nat Commun, 6, 2015
7X6L
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BU of 7x6l by Molmil
Cryo-EM structure of H3 hemagglutinin from A/HongKong/01/1968 in complex with a neutralizing antibody 28-12
Descriptor: Heavy chain of antibody 12 fab, Hemagglutinin, The light chain of the antibody 12 fab
Authors:Cong, Y, Liu, C.X.
Deposit date:2022-03-07
Release date:2022-03-23
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Unique binding pattern for a lineage of human antibodies with broad reactivity against influenza A virus.
Nat Commun, 13, 2022
4NM8
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BU of 4nm8 by Molmil
Crystal structure of broadly neutralizing antibody CR8043 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Antibody CR8043, ...
Authors:Lee, P.S, Wilson, I.A.
Deposit date:2013-11-14
Release date:2013-12-25
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (4.0041 Å)
Cite:A common solution to group 2 influenza virus neutralization.
Proc.Natl.Acad.Sci.USA, 111, 2014
4FQR
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BU of 4fqr by Molmil
Crystal structure of broadly neutralizing antibody C05 bound to H3 influenza hemagglutinin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Broadly neutralizing antibody C05, ...
Authors:Ekiert, D.C, Wilson, I.A.
Deposit date:2012-06-25
Release date:2012-09-19
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (4.1 Å)
Cite:Cross-neutralization of influenza A viruses mediated by a single antibody loop.
Nature, 489, 2012
7K3A
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BU of 7k3a by Molmil
Structure of full-length influenza HA with a head-binding antibody at pH 5.2, conformation B, fusion peptide release
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ...
Authors:Gui, M, Gao, J, Xiang, Y.
Deposit date:2020-09-10
Release date:2020-11-11
Last modified:2020-12-09
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural intermediates in the low pH-induced transition of influenza hemagglutinin.
Plos Pathog., 16, 2020
4FQY
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BU of 4fqy by Molmil
Crystal structure of broadly neutralizing antibody CR9114 bound to H3 influenza hemagglutinin
Descriptor: Antibody CR9114 heavy chain, Antibody CR9114 light chain, Hemagglutinin HA1, ...
Authors:Ekiert, D.C, Dreyfus, C, Wilson, I.A.
Deposit date:2012-06-25
Release date:2012-08-22
Last modified:2018-01-31
Method:X-RAY DIFFRACTION (5.253 Å)
Cite:Highly conserved protective epitopes on influenza B viruses.
Science, 337, 2012
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